Biomolecules
I. They activate many enzymes
II. They participate in the oxidation of glucose to produce ATP
III. Along with sodium ions they are responsible for the transmission of nerve signals
| Item I | Item II | ||
|---|---|---|---|
| (A) | Ester test | (P) | Tyr |
| (B) | Carbylamine test | (Q) | Asp |
| (C) | Phthalein dye test |
(R) | Ser |
| (S) | Lys | ||
Gly, Asp, Lys, Arg
The correct structure(s) of $\beta $-$L$-glucopyranose is (are) :
The pI (isoelectric point) of aspartic acid is :
For "invert sugar", the correct statement(s) is(are)
(Given : specific rotations of (+)-sucrose, (+)-maltose, L-($-$)-glucose and L-(+)-fructose in aqueous solution are +66$^\circ$, +140$^\circ$, $-$52$^\circ$ and +92$^\circ$, respectively.)
The structure of D-(+)-glucose is
The structure of L-($-$)-glucose is
Explanation:
(A) is glycine which is only naturally occurring amino acid. While (B), (C) and (D) are not the naturally occurring amino acids. Hence, correct integer is (1).
Explanation:
The structure of melamine is :
Each nitrogen has one lone pair of electrons. Number (no.) of nitrogen in a molecule $=6$
Total no. of lone pairs in melamine
$ \begin{aligned} & =\text { No. of nitrogen } \times \text { lone pair } \\\\ & =6 \times 1=6 \end{aligned} $
Hence, total number of lone pair on nitrogen is 6.
A tetrapeptide has $-$COOH group on alanine. This produces glycine (Gly), valine (Val), phenyl alanine (Phe) and alanine (Ala), on complete hydrolysis. For this tetrapeptide, the number of possible sequences (primary structures) with $-$NH2 group attached to a chiral center is _______.
Explanation:
The possible combinations with C-terminal as alanine and N-terminal with chiral carbon (i.e. excluding glycine) are four.
Val$-$Phe$-$Gly$-$Ala
Val$-$Gly$-$Phe$-$Ala
Phe$-$Val$-$Gly$-$Ala
Phe$-$Gly$-$Val$-$Ala
The substituents R1 and R2 for nine peptides are listed in the table given below. How many of these peptides are positively charged at pH = 7.0 ?
| Peptide | ${R_1}$ | ${R_2}$ |
|---|---|---|
| I | H | H |
| II | H | $C{H_3}$ |
| III | $C{H_2}COOH$ | H |
| IV | $C{H_2}CON{H_2}$ | ${(C{H_2})_4}N{H_2}$ |
| V | $C{H_2}CON{H_2}$ | $C{H_2}CON{H_2}$ |
| VI | ${(C{H_2})_4}N{H_2}$ | ${(C{H_2})_4}N{H_2}$ |
| VII | $C{H_2}COOH$ | $C{H_2}CON{H_2}$ |
| VIII | $C{H_2}OH$ | ${(C{H_2})_4}N{H_2}$ |
| IX | ${(C{H_2})_4}N{H_2}$ | $C{H_3}$ |
Explanation:
For basic amino acids with pH > 7, peptides will exist as cations. For example, when the substituents are basic, that is R1 = CH2CONH2 and R2 = (CH2)4NH2 or when R1 = (CH2)4NH2 and R2 = (CH2)4NH2 or when R1 = CH2OH and R2 = (CH2)4NH2 or when R1 = (CH2)4NH2 and R2 = CH3.
A decapeptide (mol. wt. 796) on complete hydrolysis gives glycine (mol. wt. 75), alanine and phenylalanine. Glycine contributes 47.0% to the total weight of the hydrolysed products. The number of glycine units present in the decapeptide is _________.
Explanation:
(i) A decapeptide has nine peptide bonds which hydrolyzes to give ten amino acids. Each peptide bond hydrolyses, to form one molecule of water. Hence, nine molecules of water are required to hydrolysis nine peptide bonds.
$\text{Decapeptide} \xrightarrow{\text{hydrolyse} +9\, \text{H}_2\text{O}} \text{Amino acids}$
(ii) On hydrolysis a molecule of water (equivalent to 18 g) is added across each amino acid.
Mass of hydrolysed decapeptide = Mass of decapeptide + 9 \times \text{mass of each water molecule}
$= 796 \, \text{g mol}^{-1} + 9 \times 18 \, \text{g mol}^{-1} $
$= (796 + 162) \, \text{g mol}^{-1} $
$= 958 \, \text{g mol}^{-1} $
Mass of glycine in hydrolysed decapeptide
$= \frac{47}{100} \times 958 \, \text{g mol}^{-1} $
$= 450.26 \, \text{g mol}^{-1} $
Mass of each glycine = 75 $\, \text{g mol}^{-1}$
Number of glycine units
$= \frac{\text{Mass of hydrolysed decapeptide}}{\text{Mass of each glycine}} $
$n = \frac{450.26 \, \text{g mol}^{-1}}{75 \, \text{g mol}^{-1}} $
$n = 6.00$
Hence, there are six molecules of water in decapeptide.
The following carbohydrate is
The total number of basic groups in the following form of lysine is
Explanation:
There are two basic groups in lysine
The correct statement about the following disaccharide is :
The correct statement(s) about the following sugar X and Y is(are)
Cellulose upon acetylation with excess acetic anhydride/H$_2$SO$_4$ (catalytic) gives cellulose triacetate whose structure is :
Statement-1 : Glucose gives a reddish-brown precipitate with Fehling's solution.
Statement-2 : Reaction of glucose with Fehling's solution gives $\mathrm{CuO}$ and gluconic acid.
