Principles of Inheritance and Variation

184 Questions Start NEET Test
2019 Q51 NEET MCQ
10 Mar 2026
A gene locus has two alleles A, a. If the frequency of dominant allele A is 0.4, then what will be the frequency of homozygous dominant, heterozygous and homozygous recessive individuals in the population?
A.
0.16(AA); 0.48 (Aa); 0.36(aa)
B.
0.16 (AA); 0.36(Aa); 0.48(aa)
C.
0.36 (AA); 0.48 (Aa); 0.16 (aa)
D.
0.16 (AA); 0.24 (Aa); 0.36 (aa)
2019 Q52 NEET MCQ
10 Mar 2026
What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia, and is sterile?
A.
Edward syndrome
B.
Down’s syndrome
C.
Turner’s syndrome
D.
Klinefelter’s syndrome
2019 Q53 NEET MCQ
10 Mar 2026
What map unit (Centimorgan) is adopted in the construction of genetic maps?
A.
A unit of distance between genes on chromosomes, representing 1% cross over.
B.
A unit of distance between genes on chromosomes, representing 50% cross over.
C.
A unit of distance between two expressed genes, representing 10% cross over.
D.
A unit of distance between two expressed genes, representing 100% cross over.
2019 Q54 NEET MCQ
10 Mar 2026
In Antirrhinum (Snapdragon), a red flower was crossed with a white flower and in F1 generation, pink flowers were obtained. When pink flowers were selfed, the F2 generation showed white, red and pink flowers. Choose the incorrect statement from the following :
A.
Ratio of F2 is ${1 \over 4}$ (Red) : ${2 \over 4}$ (Pink) : ${1 \over 4}$ (White)
B.
Law of Segregation does not apply in this experiment
C.
This experiment does not follow the Principle of Dominance
D.
Pink colour in F1 is due to incomplete dominance
2019 Q55 NEET MCQ
10 Mar 2026
The frequency of recombination between gene pairs on the same chromosome as a measure of the distance between genes was explained by :
A.
Alfred Sturtevant
B.
Gregor J. Mendel
C.
Sutton Boveri
D.
T.H. Morgan
2019 Q56 NEET MCQ
10 Mar 2026
Select the incorrect statement.
A.
In domesticated fowls, sex of progeny depends on the type of sperm rather than egg.
B.
Human males have one of their sex-chromosome much shorter than the other.
C.
Male fruit fly is heterogametic
D.
In male grasshoppers, 50% of sperms have no sex-chromosome.
2019 Q57 AIIMS MCQ
10 Mar 2026

Mark the incorrect statement for inbreeding.

A.
Inbreeding depression increases productivity
B.
Inbreeding depression can be overcome by outcrossing
C.
Produces purelines
D.
Increases homozygosity
2019 Q58 AIIMS MCQ
10 Mar 2026

Match the following columns and choose the correct option from the codes given below.

Column I Column II
A. Pleiotropic gene (i) Both alleles express equally
B. Co-dominance (ii) Change in nucleotides
C. Epistasis (iii) One gene shows multiple phenotypic expression
D. Mutation (iv) Non-allelic gene inheritance

A.
A - (i), B - (ii), C - (iii), D - (iv)
B.
A - (ii), B - (iii), C - (iv), D - (i)
C.
A - (iii), B - (i), C - (iv), D - (ii)
D.
A - (i), B - (iii), C - (iv), D - (ii)
2019 Q59 AIIMS MCQ
10 Mar 2026

Blood group of the father is ‘A’ and blood group of mother is ‘B’. Then predict the blood group of the progeny

A.
A, AB
B.
A, B, AB, O
C.
B, AB
D.
O, A, B
2019 Q60 AIIMS MCQ
10 Mar 2026

Assertion : Down’s syndrome, Klinefelter’s syndrome and Turner’s syndrome are chromosomal disorders.

Reason : In Klinefelter’s syndrome females are sterile.

A.
If both assertion and reason are true and reason is the correct explanation of assertion.
B.
If both assertion and reason are true, but reason is not the correct explanation of assertion.
C.
If assertion is true, but reason is false.
D.
If both assertion and reason are false.
2018 Q61 NEET MCQ
10 Mar 2026
Which of the following pairs is wrongly matched?
A.
Starch synthesis in pea : Multiple alleles
B.
ABO blood grouping : Co-dominance
C.
XO type sex determination: Grasshopper
D.
T.H. Morgan : Linkage
2018 Q62 NEET MCQ
10 Mar 2026
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by
A.
only daughters
B.
only sons
C.
only grandchildren
D.
both sons and daughters
2018 Q63 NEET MCQ
10 Mar 2026
Which of the following characteristics represent 'Inheritance of blood groups' in humans?
a. Dominance
b. Co-dominance
c. Multiple allele
d. Incomplete dominance
e. Polygenic inheritance
A.
b, c and e
B.
a, b and c
C.
b, d and e
D.
a, c and e
2018 Q64 AIIMS MCQ
10 Mar 2026

Select the incorrect statement(s) from the options given below with respect to dihybrid cross.

I. Tightly linked genes on the same chromosome show higher recombinations.

II. Genes far apart on the same chromosome show very few recombinations.

III. Genes loosely linked on the same chromosome show similar recombinations.

A.
I and II
B.
III and II
C.
I and III
D.
All of these
2018 Q65 AIIMS MCQ
10 Mar 2026

A normal woman whose father was colourblind, marries a normal man. What kinds of children can be expected and in what proportion?

A.
All daughters normal, $50 \%$ of sons colourblind
B.
All daughters normal, all sons colourblind
C.
$50 \%$ daughters colourblind, all sons normal
D.
All daughters colourblind, all sons normal
2018 Q66 AIIMS MCQ
10 Mar 2026

Which one of the following conditions correctly describes the manner of determining the sex?

A.
Homozygous sex chromosomes (ZZ) determine female sex in birds
B.
XO type of sex chromosomes determine male sex in grasshopper
C.
XO condition in humans as found in Turner's syndrome determines female sex
D.
Homozygous sex chromosomes (XX) produce males in Drosophila
2018 Q67 AIIMS MCQ
10 Mar 2026

Assertion Phenylketonuria is recessive hereditary disease caused by body’s failure to oxidise an amino acid phenylalanine to tyrosine, because of defective enzyme.

Reason It is characterised by in the presence of phenylalanine acid in urine.

A.
Both A and R are true and R is the correct explanation of A
B.
Both A and R are true, but R is not the correct explanation of A
C.
A is true, but R is false
D.
A and R are false
2018 Q68 AIIMS MCQ
10 Mar 2026

Assertion The non-allelic genes for red hair and prickles are usually inherited together.

Reason The genes for red hair and prickles are located on the same chromosome in close association.

A.
Both A and R are true and R is the correct explanation of A
B.
Both A and R are true, but R is not the correct explanation of A
C.
A is true, but R is false
D.
A and R are false
2017 Q69 NEET MCQ
10 Mar 2026
A disease caused by an autosomal primary non-disjunction is :
A.
Klinefelter's Syndrome
B.
Down's Syndrome
C.
Turner's Syndrome
D.
Sickle Cell Anemia
2017 Q70 NEET MCQ
10 Mar 2026
Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement.
A.
Both are due to a qualitative defect in globin chain synthesis
B.
Thalassemia is due to less synthesis of globin molecules
C.
Sickle cell anemia is due to a quantitative problem of globin molecules
D.
Both are due to a quantitative defect in globin chain synthesis
2017 Q71 NEET MCQ
10 Mar 2026
Which one from those given below is the period for Mendel’s hybridisation experiments ?
A.
1870 – 1877
B.
1857 – 1869
C.
1840 – 1850
D.
1856 – 1863
2017 Q72 NEET MCQ
10 Mar 2026
Among the following characters, which one was not considered by Mendel in his experiments on pea?
A.
Stem-Tall or dwarf
B.
Pod-Inflated or constricted
C.
Trichomes-Glandular or non-glandular
D.
Seed-Green or yellow
2017 Q73 NEET MCQ
10 Mar 2026
The genotypes of a Husband and Wife are IAIB and IAi.
Among the blood types of their children, how many different genotypes and phenotypes are possible?
A.
4 genotypes ; 3 phenotypes
B.
4 genotypes ; 4 phenotypes
C.
3 genotypes ; 4 phenotypes
D.
3 genotypes ; 3 phenotypes
2016 Q74 NEET MCQ
10 Mar 2026
The mechanism that causes a gene to move from one linkage group to another is called
A.
crossing-over
B.
translocation
C.
duplication
D.
inversion
2016 Q75 NEET MCQ
10 Mar 2026
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is
A.
0.75
B.
0.5
C.
0
D.
1
2016 Q76 NEET MCQ
10 Mar 2026
Pick out the correct statements :
(a) Haemophilia is a sex-linked recessive disease.
(b) Down's syndrome is due to aneuploidy.
(c) Phenylketonuria is an autosomal recessive gene disorder.
(d) Sickle cell anaemia is an X – linked recessive gene disorder.
A.
(a), (b) and (c) are correct
B.
(a), (c) and (d) are correct.
C.
(a) and (d) are correct
D.
(b) and (d) are correct.
2016 Q77 NEET MCQ
10 Mar 2026
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is contaning more number of chromosomes as compared to other dividing cells. This would results in -
A.
Polyteny
B.
Aneuploidy
C.
Polyploidy
D.
Somaclonal variation
2016 Q78 NEET MCQ
10 Mar 2026
Match the terms in Column-I with their description in Column-II and choose the correct option :
Column-I Column-II
(a) Dominance (i) Many genes govern a single character
(b) Codominance (ii) In a heterozygous organism only one allele expresses
itself
(c) Pleiotropy (iii) In a heterozygous organism both alleles express
themselves fully
(d) Polygenic inheritance (iv) A single gene influences many characters
A.
(a) - (ii), (b) - (iii), (c) - (iv), (d) - (i)
B.
(a) - (iv), (b) - (i), (c) - (ii), (d) - (iii)
C.
(a) - (ii), (b) - (ii), (c) - (iv), (d) - (iii)
D.
(a) - (iv), (b) - (iii), (c) - (i), (d) - (ii)
2016 Q79 NEET MCQ
10 Mar 2026
Which of the following most appropriately describes haemophilia ?
A.
Chromosomal disorder
B.
X-linked recessive gene disorder
C.
Dominant gene disorder
D.
Recessive gene disorder
2016 Q80 NEET MCQ
10 Mar 2026
In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant-typeoffspring. This indicates
A.
Both of the characters are controlled by more than one gene
B.
The two genes are linked and present on the same chromosome
C.
The two genes are located on two different chromosomes
D.
Chromosomes failed to separate during meiosis
2016 Q81 NEET MCQ
10 Mar 2026
A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant. When the F1 plants were selfed the resulting genotypes were in the ratio of -
A.
3 : 1 :: Tall : Dwarf
B.
1 : 2 : 1 :: Tall heterozygous : Tall homozygous : Dwarf
C.
1 : 2 : 1 :: Tall homozygous : Tall heterozygous : Dwarf
D.
3 : 1 :: Dwarf : Tall
2015 Q82 NEET MCQ
10 Mar 2026
A pleiotropic gene -
A.
is a gene evolved during Pliocene
B.
is expressed only in primitive plants
C.
Controls multiple traits in an individual
D.
controls a trait only in combination with anther gene
2015 Q83 NEET MCQ
10 Mar 2026
A gene showing codominance has :
A.
alleles tightly linked on the same chromosome
B.
one allele dominant on the other
C.
both alleles independently expressed in the heterozygote
D.
alleles that are recessive to each other
2015 Q84 NEET MCQ
10 Mar 2026
In his classic experiments on pea plants, Mendel did not use :
A.
Seed colour
B.
Flower position
C.
Seed shape
D.
Pod length
2015 Q85 NEET MCQ
10 Mar 2026
The term "linkage" was coined by -
A.
G. Mendel
B.
T.H. Morgan
C.
W. Sutton
D.
T. Boveri
2015 Q86 NEET MCQ
10 Mar 2026
In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. NEET 2015 Biology - Principles of Inheritance and Variation Question 159 English
A.
X-linked dominant
B.
Autosomal dominant
C.
Autosomal recessive
D.
X-linked recessive
2015 Q87 NEET MCQ
10 Mar 2026
A colour blind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their grandson being colour blind?
A.
1
B.
Nil
C.
0.25
D.
0.5
2015 Q88 NEET MCQ
10 Mar 2026
A man with blood group ‘A’ marries a woman with blood group ‘B’. What are all the possible blood groups of their offsprings?
A.
A and B only
B.
A, B, AB and O
C.
A, B and AB only
D.
O only
2015 Q89 NEET MCQ
10 Mar 2026
Multiple alleles are present
A.
on different chromosomes
B.
at the same locus of the chromosome
C.
at different loci on the same chromosome.
D.
on non-sister chromatids
2015 Q90 NEET MCQ
10 Mar 2026
How many pairs of contrasting characters in pea plants were studied by Mendel in his experiments?
A.
Eight
B.
Five
C.
Seven
D.
Six
2015 Q91 NEET MCQ
10 Mar 2026
Alleles are
A.
true breeding homozygotes
B.
different phenotype
C.
heterozygotes
D.
different molecular forms of a gene
2015 Q92 NEET MCQ
10 Mar 2026
An abnormal human baby with ‘XXX’ sex chromosomes was born due to
A.
formation of abnormal sperms in the father
B.
fusion of two ova and one sperm
C.
formation of abnormal ova in the mother
D.
fusion of two sperms and one ovum
2015 Q93 NEET MCQ
10 Mar 2026
The movement of a gene from one linkage group to another is called
A.
inversion
B.
translocation
C.
duplication
D.
crossing over
2014 Q94 NEET MCQ
10 Mar 2026
A human female with Turner’s syndrome :
A.
is able to produce children with normal husband.
B.
has 45 chromosomes with XO.
C.
exhibits male characters.
D.
has one additional X chromosome.
2014 Q95 NEET MCQ
10 Mar 2026
Fruit colour in squash is an example of :
A.
Recessive epistasis
B.
Dominant epistasis
C.
Complementary genes
D.
Inhibitory genes
2014 Q96 NEET MCQ
10 Mar 2026
A man whose father was colour blind marries a women who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?
A.
50%
B.
25%
C.
0%
D.
75%
2013 Q97 NEET MCQ
10 Mar 2026
Down's syndrome in humans is due to :
A.
Three 'X' chromosomes
B.
Monosomy
C.
Three copies of chromosome 21
D.
Two 'Y' chromosomes
2013 Q98 NEET MCQ
10 Mar 2026
Which one is the incorrect statement with regards to the importance of pedigree analysis?
A.
It confirms that DNA is the carrier of genetic information
B.
It helps to trace the inheritance of a specific trait
C.
It confirms that the trait is linked to one of the autosome
D.
It helps to understand whether the trait in question is dominant or recessive
2013 Q99 NEET MCQ
10 Mar 2026
Which idea is depicted by a cross in which the F1 generation resembles both the parents?
A.
law of dominance
B.
co-dominance
C.
incomplete dominance
D.
inheritance of one gene
2013 Q100 NEET MCQ
10 Mar 2026
If both parents are carriers for thalessemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child ?
A.
100%
B.
25%
C.
no chance
D.
50%