Diacetylmorphine is a semi-synthetic opioid synthesized from morphine, a derivative of the opium poppy. It is more commonly known by its street name "heroin," but it is also sometimes referred to as "smack."
Amphetamine, barbiturates, and crack are different types of drugs. Amphetamines are a type of stimulant, barbiturates are depressants, and crack is a form of cocaine that can be smoked.
Select the correct sequential steps regarding
absorption of fatty acids and glycerol, in intestine.
(A) Micelles are reformed into small protein coated
fat globules called chylomicrons.
(B) Micelles move into intestinal mucosa.
(C) Fatty acids and glycerol are incorporated into
small droplets called micelles.
(D) Lacteals release the absorbed substances into
blood stream.
(E) Chylomicrons are transported into lacteals.
Choose the correct answer from the options given
below :
A.
(A), (E), (B), (D), (C)
B.
(D), (E), (B), (C), (A)
C.
(C), (B), (A), (E), (D)
D.
(B), (C), (E), (A), (D)
Correct Answer: C
Explanation:
The correct answer is :
Option C : (C), (B), (A), (E), (D)
Explanation :
The steps in the digestion and absorption of fatty acids and glycerol in the intestine are as follows :
(C) Fatty acids and glycerol are incorporated into small droplets called micelles. These micelles are formed in the lumen of the small intestine.
(B) Micelles move into intestinal mucosa. They break down, releasing the fatty acids and glycerol, which then diffuse into the cells of the intestinal mucosa.
(A) Within these cells, the fatty acids and glycerol are reassembled into triglycerides. These triglycerides are then packaged with proteins and other substances into tiny, protein-coated fat globules called chylomicrons.
(E) The chylomicrons are extruded from the cells into the lymphatic system - specifically into tiny lymph vessels in the intestinal wall called lacteals.
(D) These lacteals ultimately transport the chylomicrons, and therefore the digested fat, into the bloodstream. The absorbed substances are then circulated to cells throughout the body.
Once the undigested and unabsorbed substances enter the caecum, their backflow is prevented by
A.
Ileo-caecal valve
B.
Gastro-oesophageal sphincter
C.
Pyloric sphincter
D.
Sphincter of Oddi
Correct Answer: A
Explanation:
Option (A) is the correct answer because the undigested food (faeces) enters into caecum of the large
intestine through ileo-caecal valve, which prevents the backflow of the faecal matter.
Option (B) is not the answer because a muscular sphincter i.e., the gastro-oesophageal sphincter
regulates the opening of oesophagus into the stomach.
Option (C) is not the answer because pyloric sphincter regulates the opening in between stomach and
duodenum.
Option (D) is not the answer because the opening of common hepato-pancreatic duct is guarded by
sphincter of Oddi.
Option (c) is the correct answer because enamel is the hardest substance of the body which covers the exposed part of tooth called crown and helps in mastication of food.
Option (a) is incorrect because basic shape of teeth is provided by dentine which is present in crown, root and neck.
Option (b) is incorrect because neck of tooth connects crown with root.
Option (d) is incorrect because bolus is masticated food mixed with saliva which is ready for swallowing.
Statement I : Fatty acids and glycerols cannot be absorbed into the blood.
Statement II : Specialized lymphatic capillaries called lacteals carry chylomicrons into lymphatic vessels and ultimately into the blood.
In the light of the above statements, choose the most appropriate answer from the options given below:
A.
Both Statement I and Statement II are correct
B.
Both Statement I and Statement II are incorrect
C.
Statement I is correct but Statement II is incorrect
D.
Statement I is incorrect but Statement II is correct
Correct Answer: A
Explanation:
Option (a) is the correct answer because both the statements I and II are correct as fatty acids and glycerol being insoluble in water, cannot be absorbed into the blood. They are first incorporated into small droplets called micelles which move into the intestinal mucosa. They are re-formed into very small protein coated fat globules called chylomicrons which are transported into the lymph vessels (lacteals) in the villi. The lymph vessels ultimately release the absorbed substances into the blood stream.
Which of the following functions is not performed by secretions from salivary glands?
A.
Control bacterial population in mouth
B.
Digestion of complex carbohydrates
C.
Lubrication of oral cavity
D.
Digestion of disaccharides
Correct Answer: D
Explanation:
Option (d) is the correct answer because digestion of polysaccharides like starch occurs in mouth and digestion of disaccharides occurs in small intestine.
Option (c) is incorrect because saliva contains mucus which helps in the lubrication of oral cavity.
Option (a) is incorrect because saliva contains an antibacterial agent-lysozyme so that it controls bacterial population in mouth.
Option (b) is incorrect because digestion of complex carbohydrates are performed by secretions from salivary glands.
Which of the following is present between the adjacent bones of the vertebral column?
A.
Intercalated discs
B.
Cartilage
C.
Areolar tissue
D.
Smooth muscle
Correct Answer: B
Explanation:
Option (b) is the correct answer because cartilage forming the intervertebral disc is present between the adjacent bones of the vertebral column and it is a type of cartilaginous joint.
Option (c) is incorrect because areolar tissue present beneath the skin is a type of loose connective tissue.
Option (d) is incorrect because smooth muscles are present in the visceral organs.
Option (a) is incorrect because intercalated discs are characteristic feature of cardiac muscles present in heart.
$\bullet$ Option (c) is correct because succus entericus is referred to as intestinal juice. It is a fluid secreted in
small intestine in small quantity. The
secretion of the brush border cells of the
mucosa along with the secretions of
goblet cells constitute succus entericus.
It consist of various enzymes like
lipases, disaccharides, nucleosidases
etc. and mucus.
$\bullet$ Chyme is name given to acidic food present in stomach.
$\bullet$ Exocrine secretion of pancreatic acini is called pancreatic juice.
$\bullet$ Secretion of gastric glands present in stomach is called gastric juice.
$\bullet$ The bile duct and the pancreatic duct open together into the duodenum as the common hepato-pancreatic duct which is guarded by a sphincter called the sphincter of Oddi.
$\bullet$ Ileo-caecal valve is present at the junction of ileum and caecum to prevent the backflow of faecal matter into the ileum in humans.
$\bullet$ Gastro-oesphageal sphincter regulates the opening of oesophagus into stomach.
Identify the correct statement with reference to
human digestive system.
A.
Ileum opens into small intestine
B.
Vermiform appendix arises from
duodenum
C.
Serosa is the innermost layer of the
alimentary canal
D.
Ileum is a highly coiled part
Correct Answer: D
Explanation:
The option (d) is correct as ileum is a highly coiled tube with reference to human digestive system. Other option can be corrected as Serosa is the outermost layer of the alimentary canal. A narrow finger-like tubular projection, the vermiform appendix arises from caecum part of large intestine. Ileum opens into the large intestine.
It takes very long time for pineapple plants to produce flowers. Which combination of hormones can be
applied to artificially induce flowering in pineapple plants throughout the year to increase yield?
A.
Gibberellin and Abscicic acid
B.
Cytokinin and Abscisic acid
C.
Auxin and Ethylene
D.
Gibberellin and Cytokinin
Correct Answer: C
Explanation:
In Pineapple plants Auxins and Ethylene induce artificial flowering in pineapple plants throughout the year
to increase yield.
Which of the following gastric cells indirectly
help in erythropoiesis?
A.
Mucous cells
B.
Parietal cells
C.
Chief cells
D.
Goblet cells
Correct Answer: B
Explanation:
Parietal cells are source of HCl and intrinsic
factor. HCl converts iron present in diet from
ferric to ferrous form for its easier absorption
and use during erythropoiesis
A baby boy aged two years is admitted to play school and passes through a dental check-up. The dentist observed that the boy had twenty teeth. Which teeth were absent?
A.
Canines
B.
Pre-molars
C.
Molars
D.
Incisors
Correct Answer: B
Explanation:
Total number of teeth in a human child is
20. In primary dentition premolars are absent.
Which cells of 'Crypts of Lieberkuhn' secrete antibacterial lysozyme?
A.
Paneth cells
B.
Zymogen cells
C.
Kupffer cells
D.
Argentaffin cells
Correct Answer: A
Explanation:
Paneth cells, present in the bottom of crypts
of Lieberkuhn, are rich in zinc and contain acidophilic
granules. There is evidence that these cells secrete
antibacterial lysozyme. Zymogen cells or peptic cells
are present in stomach and secrete pepsinogen.
Kupffer cells are present in liver. They are phagocytic
in nature and engulf disease causing microorganisms,
dead cells, etc. Argentaffin cells, found in crypts of
Lieberkuhn, synthesise hormone secretin and 5-
hydroxytryptamine.
Which hormones do stimulate the production of pancreatic juice and bicarbonate?
A.
Angiotensin and epinephrine
B.
Gastrin and insulin
C.
Cholecystokinin and secretin
D.
Insulin and glucagon
Correct Answer: C
Explanation:
Cholecystokinin pancreozymin (CCK-PZ)
is a hormone secreted from small intestine. It
stimulates the gall bladder to release bile and pancreas
to secrete and release digestive enzymes in the
pancreatic juice. Hormone secretin is secreted from
duodenum and releases bicarbonates in the pancreatic
juice. It also increases secretion of bile and decreases
gastric secretion and motility.
The main constituent of gastric acid
is hydrochloric acid which is produced by
parietal cells (also called oxyntic cells) in the
gastric glands in the stomach.
Which of the following guards the opening of hepatopanjcreatic duct into the duodenum?
A.
Pyloric sphincter
B.
Sphincter of Oddi
C.
Semilunar valve
D.
Ileocaecal valve
Correct Answer: B
Explanation:
The sphincter of Oddi is a muscular valve
that controls the flow of digestive juices (bile and pancreatic juice) through the hepatopancreatic duct
into the duodenum.
The enzyme that is not present in succus entericus is
A.
nucleosidase
B.
lipase
C.
maltase
D.
nuclease.
Correct Answer: D
Explanation:
Succus entericus or intestinal juice
(pH = 7.8) refers to the secretion of glands of small
intestine. It contains many enzymes viz maltase,
isomaltase, lipase, lactase, -dextrinase, enterokinase,
aminopeptidase, nucleotidase, nucleosidase, etc., for
the digestion of carbohydrates, proteins, fats, nucleic
acids etc. Enzyme nuclease is not a digestive enzyme.
It is not present in any digestive juice.
2015
NEET
MCQ
iCON Education HYD, 79930 92826, 73309 72826AIPMT 2015 Cancelled Paper
Gastric juice of infants contains
A.
pepsinogen, lipase, rennin
B.
amylase, remain, pepsinogen
C.
maltase, pepsinogen, rennin
D.
nuclease, pepsinogen
Correct Answer: A
Explanation:
The secretion of the cells of the gastric
glands form gastric juice with pH 2 to 3.7. It contains
two proenzymes, pepsinogen and prorennin and
enzyme gastric lipase, mucous and hydrochloric acid.
Rennin (chymosin) is responsible for clotting milk
by acting on soluble milk protein caseinogen, and
converting it into insoluble casein. This ensures that
milk remains in stomach long enough to be acted on
by protein digesting enzymes. Rennin’s concentration
is highest in young mammals (as their primary diet is
milk) which reduces gradually with age.
2015
NEET
MCQ
iCON Education HYD, 79930 92826, 73309 72826AIPMT 2015 Cancelled Paper
Which of the following statements is not correct?
A.
Oxyntic cells are present in the mucosa of stomach and secrete HCl.
B.
Acini are present in the pancreas and secrete carboxypeptidase.
C.
Brunner's glands are present in the submucosa of stomach and secrete pepsinogen.
D.
Goblet cells are present in the mucosa of intestine and secrete mucus.
Correct Answer: C
Explanation:
Duodenum contains Brunner’s glands
which secrete mucus and digestive juices.
Fructose is absorbed into the blood through mucosa cells of intesine by the process called
A.
active transport
B.
facilitated transport
C.
simple diffusion
D.
co-transport mechanism.
Correct Answer: B
Explanation:
Facilitated transport is a form of passive
transport in which materials are moved across
the plasma membrane by a transport protein
down their concentration gradient; hence, it
does not require energy.
The initial step in the digestion of milk in humans is carried out by
A.
lipase
B.
trypsin
C.
rennin
D.
pepsin.
Correct Answer: C
Explanation:
Rennin (also called chymosin) is an
enzyme that occurs in gastric juice and is a
constituent of rennet. It coagulates milk by
converting caseinogen to casein. The initial
step in the digestion of milk in humans is
carried out by rennin.
A healthy person eats the following diet-5 gm raw sugar, 4 gm albumin, 10 gm pure buffalo ghee adultrated with 2 gm vegetable ghee (hydrogenated vegetable oil) and 5 gm lignin. How many calories he is likely to get?
A.
126
B.
164
C.
112
D.
144
Correct Answer: D
Explanation:
Physiological value is the energy produced
by 1 gm of food on oxidation in the body. For
carbohydrates it is 4.0 Kcal/g, for proteins it is
4.0 Kcal/g and it is 9.0 Kcal/g for fats. Lignin is a
fibre that is present in plant cells but it does not
produce energy. Hence,
5 g raw sugar will yield 5 × 4.0 = 20.0 Kcal
4 g albumin will yield 4 × 4.0 = 16.0 Kcal
(10 + 2) g of fat will yield 12 × 9.0 = 108.0 Kcal
Total yield = 144 Kcal.
Chemical process of digestion starts in
the oral cavity by the hydrolytic action of the
carbohydrate splitting enzyme, the salivary
amylase. Carbohydrates in the chyme are
hydrolysed by pancreatic amylase into
disaccharides
Select the correct match of the digested products in humans given in column ${\rm I}$ with their absorption site and mechanism in column ${\rm I}$${\rm I}$.
A.
Column ${\rm I}$
Column ${\rm I}$${\rm I}$
Glycerol, fatty acids
Duodenum, move as chylomicrons
B.
Column ${\rm I}$
Column ${\rm I}$${\rm I}$
Cholesterol, maltose
Large intestine, active absorption
C.
Column ${\rm I}$
Column ${\rm I}$${\rm I}$
Glycine, glucose
Small intestine, active absorption
D.
Column ${\rm I}$
Column ${\rm I}$${\rm I}$
Fructose, Na+
Small intestine, passive absorption
Correct Answer: C
Explanation:
Small intestine is major area of
absorbtion of nutrients. Approximately
80% of absorbtion take place here. Glucose,
fructose, fatty acids, amino acids (Glycine
etc.) are absorbed through mucosa into
blood and lymph by active absorbtion.
Where do certain symbiotic microorganisms normally occur in human body?
A.
Caecum
B.
Oral lining and tongue surface
C.
Vermiform appendix and rectum
D.
Duodenum
Correct Answer: A
Explanation:
The caecum is a pouch-like portion
of the large intestine which hosts some
symbiotic micro-organisms. The caecum
absorbs water and salts from undigested
foods before they continue on to the large
intestine.
Carboxypeptidase is an exopeptidase
enzyme secreted by the pancreas that acts
only on the peptide linkage of a terminal amino acid containing a free carboxyl group.
Zinc is a cofactor for carboxypeptidase. In
Digestion of carboxypeptidase, requires zinc
for its protein degrading action.
Anxiety and eating spicy food together in an otherwise normal human, may lead to
A.
indigestion
B.
jaundicce
C.
diarrhoea
D.
vomiting.
Correct Answer: A
Explanation:
Indigestion is the condition in which the
food is not properly digested leading to a feeling of
fullness. The causes of indigestion are inadequate
enzyme secretion, anxiety, food poisoning, over eating
and spicy food.
One of the constituents of the pancreatic juice which is poured into the duodenum in humans is
A.
trypsinogen
B.
chymotrypsin
C.
trypsin
D.
enterokinase.
Correct Answer: A
Explanation:
Duodenum follows the stomach. It is
somewhat C-shaped and about 25 cm. long. It receives
the hepatopancreatic ampulla of the hepatopancreatic
duct formed by the union of bile duct (from liver)
and pancreatic duct (from pancreas) and whose
opening is guarded by sphincter of Oddi. Pancreatic
juice contains proenzymes—trypsinogen,
chymotrypsinogen and procarboxypeptidase. In the
presence of enterokinase (a protease of intestinal
juice), inactive trypsinogen is converted to active
trypsin. Trypsin then activates chymotrypsinogen and
procarboxypeptidase into chymotrypsin and
carboxypeptidase respectively. This enables
simultaneous action of all pancreatic proteases for a
rapid digestion of proteins. The bile provides alkaline
medium for various reactions.
Two friends are eating together on a dining table. One of them suddenly starts coughing while swallowing some food. This coughing would have been due to improper movement of
A.
epiglottis
B.
diaphragm
C.
neck
D.
tounge.
Correct Answer: A
Explanation:
This coughing would have been due to
improper movement of epiglottis. Epiglottis is present
in the laryngopharynx, which is the lowest part of
pharynx. Laryngopharynx possess two apertures -
anterior slit-like glottis and posterior gullet. Glottis
leads into trachea or wind pipe, which is closed by
bilobed leaf-like cartilage, the epiglottis, during the
swallowing of food-bolus. Hence, during eating one
may suddenly coughs due to opening of epiglottis and
movement of some food particles in the trachea.
If for some reason the parietal cells of the gut epithelium become partially non-functional, what is likely to happen?
A.
The pancreatic enzymes and specially the trypsin and lipase will not work efficiently.
B.
The pH of stomach will fall abruptly.
C.
Steapsin will be more effective.
D.
Proteins will not be adequately hydrolysed by pepsin into proteoses and peptones.
Correct Answer: D
Explanation:
Parietal or oxyntic cells secrete HCl (due to
which pH of stomach is highly acidic) and intrinsic
factor. Parietal glands also secrete pepsinogen to
which hydrochloric acid acts to convert it into pepsin.
Pepsin in return causes digestion of proteins. If
parietal cells become non-functional it will directly
affect protein digestion.
Jaundice is a disorder in which skin and
eyes turn yellow due to the deposition of bile pigment.
This happens when bile made in the liver fails to reach
the intestine due to obstruction of the bile duct. As a
result, the bile is absorbed into the blood instead of
going to the duodenum and cause yellowing of eyes
and skin.
Carrier ions like Na+ facilitate the absorption of substances like
A.
amino acids and glucose
B.
glucose and fatty acids
C.
fatty acids and glycerol
D.
fructose and some amino acids.
Correct Answer: A
Explanation:
The absorption of glucose and amino acids
is mediated by carrier ions like Na+
. The concentration
of Na+
is higher in the intestinal lumen compared to
mucosal cells. Na+
, therefore moves into the cells
along its concentration gradient and simultaneously
glucose is transported into the intestinal cells. Thus
Na+
diffuses into the cell and it drags glucose along
with it. The intestinal Na+
gradient is the immediate
energy source. The mechanism for transport of amino
acid is same as glucose.
Fructose absorption does not require energy and is
independent of Na+
transport.
If for some reason our goblet cells are nonfunctional, this will adversely affect.
A.
production of somatostain
B.
secretion of sebum from the sebaceous glands
C.
maturation of sperms
D.
smooth movement of food down the intestine.
Correct Answer: D
Explanation:
Goblet cells, found in the intestinal
mucosal epithelium, secrete mucus. The mucus lubricates the food for an easy
passage. So, if for some reason, goblet cells
become non-functional, it will adversely
affect the smooth movement of food down
the intestine.
When breast feeding is replaced by less nutritive food low in proteins and calories; the infants below the age of one year are likely to suffer from
A.
rickets
B.
kwashiorkor
C.
pellagra
D.
marasmus.
Correct Answer: D
Explanation:
Marasmus is common in infants under one
year of age. It develops due to deficiency of proteins
and calories. It can be cured by providing adequate
proteins, fats and carbohydrates.
A young infant may be feeding entirely on mother's milk which is white in colour but the stools which the infant passes out is quite yellowish. what is this yellow colour due to?
A.
Bile pigments passed through bile juice
B.
Undigested milk protein casein
C.
Pancreatic juice poured into duodenum
D.
Intestimal juice
Correct Answer: A
Explanation:
Young infant may be feeding entirely
on mother’s milk which is white in colour
but the stools which the infant passes out is
quite yellowish because of the bile pigments
passed through bile juice. Bile pigments
are any of several coloured compounds
derived from porphyrin that are found in
bile; principally bilirubin and biliverdin. Bile
pigment is produced regularly when old red
blood cells are broken down, mainly by the
spleen. In some blood-disorders where the
red cells are destroyed, more bile pigment is
produced.
Which one of the following statements is true regarding digestion and absorption of food in humans?
A.
Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions like Na+.
B.
Chylomicrons are small lipoprotein particles that are transported from intestine into blood capillaries.
C.
About 60% of starch is hydrolysed by salivary amylase in our mouth.
D.
Oxyntic cells in our stomach secrete the proenzyme pepsinogen.
Correct Answer: A
Explanation:
Glucose and galactose are absorbed by active
transport. Sodium pump of the cell membrane helps
in it active take up. Fructose is absorbed by facilitated
diffusion that involves a specific transmembrane
carrier. Amino acids are absorbed by active transport
coupled with active sodium transport. They also enter
the blood stream.
What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?
A.
In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
B.
Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin.
C.
Gastric juice will be deficient in chymosin.
D.
Gastric juice will be deficient in pepsinogen.
Correct Answer: A
Explanation:
If the secretion of parietal cells of
gastric glands is blocked with an inhibitor,
in the absence of HCI secretion, inactive
pepsinogen is not converted into the active
enzyme pepsin.