Principles of Inheritance and Variation

175 Questions Start NEET Test
2019 Q51 NEET MCQ
10 Mar 2026
A gene locus has two alleles A, a. If the frequency of dominant allele A is 0.4, then what will be the frequency of homozygous dominant, heterozygous and homozygous recessive individuals in the population?
A.
0.16(AA); 0.48 (Aa); 0.36(aa)
B.
0.16 (AA); 0.36(Aa); 0.48(aa)
C.
0.36 (AA); 0.48 (Aa); 0.16 (aa)
D.
0.16 (AA); 0.24 (Aa); 0.36 (aa)
2019 Q52 NEET MCQ
10 Mar 2026
What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia, and is sterile?
A.
Edward syndrome
B.
Down’s syndrome
C.
Turner’s syndrome
D.
Klinefelter’s syndrome
2019 Q53 NEET MCQ
10 Mar 2026
What map unit (Centimorgan) is adopted in the construction of genetic maps?
A.
A unit of distance between genes on chromosomes, representing 1% cross over.
B.
A unit of distance between genes on chromosomes, representing 50% cross over.
C.
A unit of distance between two expressed genes, representing 10% cross over.
D.
A unit of distance between two expressed genes, representing 100% cross over.
2019 Q54 NEET MCQ
10 Mar 2026
In Antirrhinum (Snapdragon), a red flower was crossed with a white flower and in F1 generation, pink flowers were obtained. When pink flowers were selfed, the F2 generation showed white, red and pink flowers. Choose the incorrect statement from the following :
A.
Ratio of F2 is ${1 \over 4}$ (Red) : ${2 \over 4}$ (Pink) : ${1 \over 4}$ (White)
B.
Law of Segregation does not apply in this experiment
C.
This experiment does not follow the Principle of Dominance
D.
Pink colour in F1 is due to incomplete dominance
2019 Q55 NEET MCQ
10 Mar 2026
The frequency of recombination between gene pairs on the same chromosome as a measure of the distance between genes was explained by :
A.
Alfred Sturtevant
B.
Gregor J. Mendel
C.
Sutton Boveri
D.
T.H. Morgan
2019 Q56 NEET MCQ
10 Mar 2026
Select the incorrect statement.
A.
In domesticated fowls, sex of progeny depends on the type of sperm rather than egg.
B.
Human males have one of their sex-chromosome much shorter than the other.
C.
Male fruit fly is heterogametic
D.
In male grasshoppers, 50% of sperms have no sex-chromosome.
2018 Q57 NEET MCQ
10 Mar 2026
Which of the following pairs is wrongly matched?
A.
Starch synthesis in pea : Multiple alleles
B.
ABO blood grouping : Co-dominance
C.
XO type sex determination: Grasshopper
D.
T.H. Morgan : Linkage
2018 Q58 NEET MCQ
10 Mar 2026
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by
A.
only daughters
B.
only sons
C.
only grandchildren
D.
both sons and daughters
2018 Q59 NEET MCQ
10 Mar 2026
Which of the following characteristics represent 'Inheritance of blood groups' in humans?
a. Dominance
b. Co-dominance
c. Multiple allele
d. Incomplete dominance
e. Polygenic inheritance
A.
b, c and e
B.
a, b and c
C.
b, d and e
D.
a, c and e
2017 Q60 NEET MCQ
10 Mar 2026
A disease caused by an autosomal primary non-disjunction is :
A.
Klinefelter's Syndrome
B.
Down's Syndrome
C.
Turner's Syndrome
D.
Sickle Cell Anemia
2017 Q61 NEET MCQ
10 Mar 2026
Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement.
A.
Both are due to a qualitative defect in globin chain synthesis
B.
Thalassemia is due to less synthesis of globin molecules
C.
Sickle cell anemia is due to a quantitative problem of globin molecules
D.
Both are due to a quantitative defect in globin chain synthesis
2017 Q62 NEET MCQ
10 Mar 2026
Which one from those given below is the period for Mendel’s hybridisation experiments ?
A.
1870 – 1877
B.
1857 – 1869
C.
1840 – 1850
D.
1856 – 1863
2017 Q63 NEET MCQ
10 Mar 2026
Among the following characters, which one was not considered by Mendel in his experiments on pea?
A.
Stem-Tall or dwarf
B.
Pod-Inflated or constricted
C.
Trichomes-Glandular or non-glandular
D.
Seed-Green or yellow
2017 Q64 NEET MCQ
10 Mar 2026
The genotypes of a Husband and Wife are IAIB and IAi.
Among the blood types of their children, how many different genotypes and phenotypes are possible?
A.
4 genotypes ; 3 phenotypes
B.
4 genotypes ; 4 phenotypes
C.
3 genotypes ; 4 phenotypes
D.
3 genotypes ; 3 phenotypes
2016 Q65 NEET MCQ
10 Mar 2026
The mechanism that causes a gene to move from one linkage group to another is called
A.
crossing-over
B.
translocation
C.
duplication
D.
inversion
2016 Q66 NEET MCQ
10 Mar 2026
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is
A.
0.75
B.
0.5
C.
0
D.
1
2016 Q67 NEET MCQ
10 Mar 2026
Pick out the correct statements :
(a) Haemophilia is a sex-linked recessive disease.
(b) Down's syndrome is due to aneuploidy.
(c) Phenylketonuria is an autosomal recessive gene disorder.
(d) Sickle cell anaemia is an X – linked recessive gene disorder.
A.
(a), (b) and (c) are correct
B.
(a), (c) and (d) are correct.
C.
(a) and (d) are correct
D.
(b) and (d) are correct.
2016 Q68 NEET MCQ
10 Mar 2026
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is contaning more number of chromosomes as compared to other dividing cells. This would results in -
A.
Polyteny
B.
Aneuploidy
C.
Polyploidy
D.
Somaclonal variation
2016 Q69 NEET MCQ
10 Mar 2026
Match the terms in Column-I with their description in Column-II and choose the correct option :
Column-I Column-II
(a) Dominance (i) Many genes govern a single character
(b) Codominance (ii) In a heterozygous organism only one allele expresses
itself
(c) Pleiotropy (iii) In a heterozygous organism both alleles express
themselves fully
(d) Polygenic inheritance (iv) A single gene influences many characters
A.
(a) - (ii), (b) - (iii), (c) - (iv), (d) - (i)
B.
(a) - (iv), (b) - (i), (c) - (ii), (d) - (iii)
C.
(a) - (ii), (b) - (ii), (c) - (iv), (d) - (iii)
D.
(a) - (iv), (b) - (iii), (c) - (i), (d) - (ii)
2016 Q70 NEET MCQ
10 Mar 2026
Which of the following most appropriately describes haemophilia ?
A.
Chromosomal disorder
B.
X-linked recessive gene disorder
C.
Dominant gene disorder
D.
Recessive gene disorder
2016 Q71 NEET MCQ
10 Mar 2026
In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant-typeoffspring. This indicates
A.
Both of the characters are controlled by more than one gene
B.
The two genes are linked and present on the same chromosome
C.
The two genes are located on two different chromosomes
D.
Chromosomes failed to separate during meiosis
2016 Q72 NEET MCQ
10 Mar 2026
A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant. When the F1 plants were selfed the resulting genotypes were in the ratio of -
A.
3 : 1 :: Tall : Dwarf
B.
1 : 2 : 1 :: Tall heterozygous : Tall homozygous : Dwarf
C.
1 : 2 : 1 :: Tall homozygous : Tall heterozygous : Dwarf
D.
3 : 1 :: Dwarf : Tall
2015 Q73 NEET MCQ
10 Mar 2026
A pleiotropic gene -
A.
is a gene evolved during Pliocene
B.
is expressed only in primitive plants
C.
Controls multiple traits in an individual
D.
controls a trait only in combination with anther gene
2015 Q74 NEET MCQ
10 Mar 2026
A gene showing codominance has :
A.
alleles tightly linked on the same chromosome
B.
one allele dominant on the other
C.
both alleles independently expressed in the heterozygote
D.
alleles that are recessive to each other
2015 Q75 NEET MCQ
10 Mar 2026
In his classic experiments on pea plants, Mendel did not use :
A.
Seed colour
B.
Flower position
C.
Seed shape
D.
Pod length
2015 Q76 NEET MCQ
10 Mar 2026
The term "linkage" was coined by -
A.
G. Mendel
B.
T.H. Morgan
C.
W. Sutton
D.
T. Boveri
2015 Q77 NEET MCQ
10 Mar 2026
In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. NEET 2015 Biology - Principles of Inheritance and Variation Question 159 English
A.
X-linked dominant
B.
Autosomal dominant
C.
Autosomal recessive
D.
X-linked recessive
2015 Q78 NEET MCQ
10 Mar 2026
A colour blind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their grandson being colour blind?
A.
1
B.
Nil
C.
0.25
D.
0.5
2015 Q79 NEET MCQ
10 Mar 2026
A man with blood group ‘A’ marries a woman with blood group ‘B’. What are all the possible blood groups of their offsprings?
A.
A and B only
B.
A, B, AB and O
C.
A, B and AB only
D.
O only
2015 Q80 NEET MCQ
10 Mar 2026
Multiple alleles are present
A.
on different chromosomes
B.
at the same locus of the chromosome
C.
at different loci on the same chromosome.
D.
on non-sister chromatids
2015 Q81 NEET MCQ
10 Mar 2026
How many pairs of contrasting characters in pea plants were studied by Mendel in his experiments?
A.
Eight
B.
Five
C.
Seven
D.
Six
2015 Q82 NEET MCQ
10 Mar 2026
Alleles are
A.
true breeding homozygotes
B.
different phenotype
C.
heterozygotes
D.
different molecular forms of a gene
2015 Q83 NEET MCQ
10 Mar 2026
An abnormal human baby with ‘XXX’ sex chromosomes was born due to
A.
formation of abnormal sperms in the father
B.
fusion of two ova and one sperm
C.
formation of abnormal ova in the mother
D.
fusion of two sperms and one ovum
2015 Q84 NEET MCQ
10 Mar 2026
The movement of a gene from one linkage group to another is called
A.
inversion
B.
translocation
C.
duplication
D.
crossing over
2014 Q85 NEET MCQ
10 Mar 2026
A human female with Turner’s syndrome :
A.
is able to produce children with normal husband.
B.
has 45 chromosomes with XO.
C.
exhibits male characters.
D.
has one additional X chromosome.
2014 Q86 NEET MCQ
10 Mar 2026
Fruit colour in squash is an example of :
A.
Recessive epistasis
B.
Dominant epistasis
C.
Complementary genes
D.
Inhibitory genes
2014 Q87 NEET MCQ
10 Mar 2026
A man whose father was colour blind marries a women who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?
A.
50%
B.
25%
C.
0%
D.
75%
2013 Q88 NEET MCQ
10 Mar 2026
Down's syndrome in humans is due to :
A.
Three 'X' chromosomes
B.
Monosomy
C.
Three copies of chromosome 21
D.
Two 'Y' chromosomes
2013 Q89 NEET MCQ
10 Mar 2026
Which one is the incorrect statement with regards to the importance of pedigree analysis?
A.
It confirms that DNA is the carrier of genetic information
B.
It helps to trace the inheritance of a specific trait
C.
It confirms that the trait is linked to one of the autosome
D.
It helps to understand whether the trait in question is dominant or recessive
2013 Q90 NEET MCQ
10 Mar 2026
Which idea is depicted by a cross in which the F1 generation resembles both the parents?
A.
law of dominance
B.
co-dominance
C.
incomplete dominance
D.
inheritance of one gene
2013 Q91 NEET MCQ
10 Mar 2026
If both parents are carriers for thalessemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child ?
A.
100%
B.
25%
C.
no chance
D.
50%
2013 Q92 NEET MCQ
10 Mar 2026
Which of the following cannot be detected in a developing foetus by amniocentesis ?
A.
Sex of the foetus
B.
jaundice
C.
Klinefelter syndrome
D.
Down syndrome
2013 Q93 NEET MCQ
10 Mar 2026
If two persons with 'AB' blood group marry and have sufficiently large number of children, these children could be classified as 'A' blood group : 'AB' blood group : 'B' blood group in 1 : 2 : 1 ratio. Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in 'AB' blood group individuals. This is an example of :
A.
Codominance
B.
Partial dominance
C.
Incomplete dominance
D.
Complete dominance
2013 Q94 NEET MCQ
10 Mar 2026
Select the incorrect statement with regard to Haemophilia is :
A.
It is a dominant disease
B.
A single protein involved in the clotting of blood is affected
C.
It is a recessive disease
D.
It is a sex-linked disease
2012 Q95 NEET MCQ
10 Mar 2026
Which one of the following is a wrong statement regarding mutations ?
A.
UV and Gamma rays are mutagens
B.
Deletion and insertion of base pairs cause frame-shift mutations
C.
Cancer cells commonly show chromosomal aberrations
D.
Change in a single base pair of DNA does not cause mutation
2012 Q96 NEET MCQ
10 Mar 2026
A test cross is carried out to :
A.
Determine whether two species or varieties will breed successfully
B.
Determine the genotype of a plant at F2
C.
Predict whether two traits are linked
D.
Assess the number of alleles of a gene
2012 Q97 NEET MCQ
10 Mar 2026
Represented below is the inheritance pattern of the certain type of traits in humans. Which one of the following conditions could be an example of this pattern ? AIPMT 2012 Mains Biology - Principles of Inheritance and Variation Question 145 English
A.
Haemophilia
B.
Sickel cell anaemia
C.
Thalassemia
D.
Phenylketonuria
2012 Q98 NEET MCQ
10 Mar 2026
F2 generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same as 1 : 2 : 1. It represents a case of
A.
Monohybrid cross with incomplete dominance
B.
Co - dominance
C.
Monohybrid cross with complete dominance
D.
Dihybrid cross
2012 Q99 NEET MCQ
10 Mar 2026
A normal - visioned man whose father was colour bilind, marries a woman whose father was also colour - blind. They have their first child as a daughter. What are the chances that this child would be colour blind
A.
50%
B.
25%
C.
100%
D.
Zero percent
2011 Q100 NEET MCQ
10 Mar 2026
Test cross in plants or in Drosophila involves crossing :
A.
the F1 hybrid with a double recessive genotype
B.
between two genotypes with dominant trait
C.
between two F1 hybrids
D.
between two genotypes with recessive trait