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Molecular Basis of Inheritance

180 Questions
All Exams NEET AIIMS
2013 NEET MCQ
NEET 2013 (Karnataka)
Which of the following is not a property of the genetic code ?
A.
Ambiguous
B.
Universal
C.
Degeneracy
D.
Non-overlapping
2013 NEET MCQ
NEET 2013 (Karnataka)
Satellite RNA are present in some :
A.
Prions
B.
Bacteriophages
C.
Plant viruses
D.
Viroids
2013 NEET MCQ
NEET 2013 (Karnataka)
Genes of interest can be selected from a genomic library by using :
A.
Restriction enzymes
B.
Gene targets
C.
Cloning vectors
D.
DNA probes
2013 NEET MCQ
NEET 2013 (Karnataka)
In an inducible operon, the genes are :
A.
usually expressed unless a signal turns them "off"
B.
always expressed
C.
never expressed
D.
usually not expressed unless a signal turns them "on"
2013 NEET MCQ
NEET 2013
Which of the following statements is not true of two genes that show 50% recombination frequency ?
A.
The genes are tightly linked
B.
The genes show independent assortment
C.
If the genes are present on the same chromosome, they undergo more than one crossovers in every meiosis.
D.
The genes may be on different chromosomes
2013 NEET MCQ
NEET 2013
The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C. NEET 2013 Biology - Molecular Basis of Inheritance Question 150 English
A.
A-translation B-extension C-Rosalind Franklin
B.
A-translation B-transcription C-Erevin Chargaff
C.
A-transcription B-translation C-Francis Crick
D.
A-transcription B-replication C-James Watson
2013 NEET MCQ
NEET 2013
Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?
A.
Transacetylase
B.
Lactose permease and transacetylase
C.
Lactose permease
D.
$\beta $-galactosidase
2012 NEET MCQ
AIPMT 2012 Prelims
Removal of introns and joining of exons in a defined order during transcription is called
A.
Looping
B.
Inducing
C.
Slicing
D.
Splicing
2012 NEET MCQ
AIPMT 2012 Prelims
Which one of the following is not a part of a transcription unit in DNA ?
A.
The structural gene
B.
the inducer
C.
A terminator
D.
A promoter
2012 NEET MCQ
AIPMT 2012 Prelims
Ribosomal RNA is actively synthesized in
A.
Nucleolus
B.
Ribosomes
C.
Lysosomes
D.
Nucleoplasm
2012 NEET MCQ
AIPMT 2012 Prelims
If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA stand sequence
A.
ATCGU
B.
UAGAC
C.
AACTG
D.
TTAGU
2012 NEET MCQ
AIPMT 2012 Prelims
Removal of RNA polymerase -III from nucleoplasm will affect the synthesis of
A.
tRNA
B.
hnRNA
C.
rRNA
D.
mRNA
2011 NEET MCQ
AIPMT 2011 Mains
The unequivocal proof of DNA as the genetic material came from the studies on a :
A.
Viroid
B.
Bacterium
C.
Fungus
D.
Bacterial virus
2011 NEET MCQ
AIPMT 2011 Prelims
What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope ?
A.
Nucleosomes
B.
Genes
C.
Nucleotides
D.
Base pairs
2010 NEET MCQ
AIPMT 2010 Mains
The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join -
A.
One nucleotide with another nucleotide
B.
One nitrogenous base with pentose sugar
C.
One nucleoside with another nucleoside
D.
One DNA strand with the other DNA strand
2010 NEET MCQ
AIPMT 2010 Mains
In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the -
A.
Dictyosomes
B.
Ribosomes
C.
Nucleus
D.
ER
2010 NEET MCQ
AIPMT 2010 Mains
Which one of the follwoing statements about the particular entity is true ?
A.
Nucleosome is formed of nucleotides
B.
Centromere is found in animals cells, which produces aster during cell division
C.
The gene for producing insulin is present in every body cell
D.
DNA consists of a core of eight histones
2010 NEET MCQ
AIPMT 2010 Mains
The lac Operon consists of -
A.
Three regulatory genes and three structure genes
B.
Four regulatory genes only
C.
Two regulatory genes and two structural genes
D.
One regulatory gene and three structural genes
2010 NEET MCQ
AIPMT 2010 Prelims
Select the two correct statements out of the four (a-d) statements given below about lac operon.
(a) Glucose or galactose may bind with the repressor and inactivate it
(b) In the absence of lactose the repressor binds with the operator region
(c) The z-gene codes for permease
(d) This was elucidated by Francois Jacob and Jacque Monod
The correct statements are :
A.
(b) and (d)
B.
(a) and (b)
C.
(b) and (c)
D.
(a) and (c)
2010 NEET MCQ
AIPMT 2010 Prelims
Which one of the following does not follow the central dogma of molecular biology ?
A.
Mucor
B.
HIV
C.
Chlamydomonas
D.
Pea
2010 NEET MCQ
AIPMT 2010 Prelims
The one aspect which is not a salient feature of genetic code, is its being –
A.
Specific
B.
Degenerate
C.
Ambiguous
D.
Universal
2010 NEET MCQ
AIPMT 2010 Prelims
Which one of the following palindromic base sequences in DNA can be easily cut at about the middle by some particular restriction enzyme?
A.
5' _____ CG TTCG ______ 3'
3' ______ATGGTA ______5'
B.
5'______GAATTC ______3'
3'______CTTAAG______5'
C.
5'______CACGTA______3'
3'______CTCAGT______5'
D.
5'______GATATG ______3'
3'______CTACTA ______5'
2009 NEET MCQ
AIPMT 2009
Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet" ?
A.
Nirenberg and Mathaei
B.
Morgan and Sturtevant
C.
Hershey and Chase
D.
Beadle and Tatum
2009 NEET MCQ
AIPMT 2009
Removal of introns and joining the exons in a defined order in a transcription unit is called :
A.
Transformation
B.
Capping
C.
Splicing
D.
Tailing
2009 NEET MCQ
AIPMT 2009
What is not true for genetic code?
A.
It is nearly universal
B.
A codon in mRNA is read in a noncontiguous fashion
C.
It is degenerate
D.
It is unambiguous
2009 NEET MCQ
AIPMT 2009
Semi-conservative replication of DNA was first demonstrated in :
A.
Drosophila melanogaster
B.
Streptococcus pneumoniae
C.
Salmonella typhimurium
D.
Escherichia coli
2008 NEET MCQ
AIPMT 2008
Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?
A.
Thymine, Uracil — Pyrimidines
B.
Guanine, Adenine — Purines
C.
Uracil, Cytosine — Pyrimidines
D.
Adenine, Thymine — Purines
2008 NEET MCQ
AIPMT 2008
Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?
A.
UUA, UCA — Leucine
B.
AUG, ACG — Start/Methionine
C.
UAG, UGA — Stop
D.
GUU, GCU — Alanine
2008 NEET MCQ
AIPMT 2008
Polysome is formed by
A.
several ribosomes attached to a single mRNA
B.
many ribosomes attached to a strand of endoplasmic reticulum
C.
a ribosome with several subunits
D.
ribosomes attached to each other in a linear arrangement
2008 NEET MCQ
AIPMT 2008
In the DNA molecule:
A.
the total amount of purine nucleotides and pyrimidine nucleotides is not always equal
B.
there are two strands which run antiparallel one in 5'→ 3' direction and other in 3'→ 5'
C.
there are two strands which run parallel in the 5'→ 3' direction
D.
the proportion of adenine in relation to thymine varies with the organism
2006 NEET MCQ
AIPMT 2006
Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis ?
A.
Neomycin
B.
Erythromycin
C.
Tetracycline
D.
Streptomycin
2006 NEET MCQ
AIPMT 2006
Antiparallel strands of a DNA molecule means that-
A.
The phosphate groups at the start of two DNA strands are in opposite position (pole)
B.
One strand turns anti-clockwise
C.
One strand turns clockwise
D.
The phosphate groups of two DNA stands, at their ends, share the same position
2006 NEET MCQ
AIPMT 2006
Amino acid sequence, in protein synthesis is decided by the sequence of -
A.
cDNA
B.
mRNA
C.
tRNA
D.
rRNA
2006 NEET MCQ
AIPMT 2006
One gene-one enzyme hypothesis was postulated by -
A.
A.Garrod
B.
Hershey and Chase
C.
Beadle and Tatum
D.
R. Franklin
2006 NEET MCQ
AIPMT 2006
One turn of the helix in a B-form DNA is approximately -
A.
20 nm
B.
3.4 nm
C.
2 nm
D.
0.34 nm
2005 NEET MCQ
AIPMT 2005
Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?
A.
protease
B.
Endonuclease
C.
Lipase
D.
Exonuclease
2005 NEET MCQ
AIPMT 2005
Telomerase is an enzyme which is a -
A.
RNA
B.
Repetitive DNA
C.
Simple protein
D.
Ribonucleoprotein
2005 NEET MCQ
AIPMT 2005
Using imprints from a plate with complete medium and carrying bacterial colonies, you can select streptomycin resistant mutants and prove that such mutations do not originates as adaptation. These imprints need to be used -
A.
On plates with minimal medium
B.
Only on plates with streptomycin
C.
Only on plates without streptomycin
D.
On plates with and without streptomycin
2005 NEET MCQ
AIPMT 2005
Which one of the following makes use of RNA as a template to synthesize DNA -
A.
Reverse transcriptase
B.
DNA dependant RNA polymerase
C.
RNA polymerase
D.
DNA polymerase
2005 NEET MCQ
AIPMT 2005
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called ?
A.
TATA box
B.
GGTT box
C.
CAAT box
D.
AAAT box
2005 NEET MCQ
AIPMT 2005
Protein synthesis in an animal cell occurs -
A.
On ribosomes present in the nucleolus as well as in cytoplasm
B.
On ribosomes presents in cytoplasm as well as in mitochondria
C.
Only on the ribosomes present in cytosol
D.
Only on ribosomes attached to the nuclear envelope and endoplasmic reticulum
2005 NEET MCQ
AIPMT 2005
E. coli cells with a mustard z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because -
A.
They cannot transport lactose from the medium into the cell
B.
They cannot synthesize functional beta galactosidase
C.
In the presence of glucose, E. coli cells do not utilize lactose
D.
The lac operon is constitutively active in these cells
2004 NEET MCQ
AIPMT 2004
In a mutational event, when adenine is replaced by guanine, it is a case of -
A.
Frameshift mutation
B.
Transition
C.
Transversion
D.
Transcription
2004 NEET MCQ
AIPMT 2004
Which form of RNA has a structure resembling clover leaf ?
A.
r-RNA
B.
m-RNA
C.
t-RNA
D.
hn-RNA
2004 NEET MCQ
AIPMT 2004
The following ratio is generally constant for a given species :-
A.
A + C / T + G
B.
G + C / A+ T
C.
A + G / C +T
D.
T + C / G + A
2004 NEET MCQ
AIPMT 2004
After a mutation at a genetic locus the character of an organism changes due to the change in :-
A.
Protein synthesis pattern
B.
RNA transcription pattern
C.
DNA replication
D.
Protein structure
2004 NEET MCQ
AIPMT 2004
During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the mRNA would be -
A.
UAUGC
B.
TCTGG
C.
UATGC
D.
TATGC
2003 NEET MCQ
AIPMT 2003
During translation initiation in prokaryotes, a GTP molecule is needed in : -
A.
Association of 30S mRNA with formy-lmet-tRNA
B.
Formation of formyl-met-tRNA
C.
Association of 50S subunit of ribosome with initiation complex
D.
Binding of 30S subunit of ribosome with mRNA
2003 NEET MCQ
AIPMT 2003
In the genetic code dictionary, how many codons are used to code for all the 20 essential amino acids : -
A.
64
B.
20
C.
60
D.
61
2003 NEET MCQ
AIPMT 2003
Degeneration of a genetic code is attributed to the : -
A.
Second member of a codon
B.
Third member of a codon
C.
First member of a codon
D.
Entire codon