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Molecular Basis of Inheritance

182 Questions Start NEET Test
All Exams NEET AIIMS
2015 Q101 NEET MCQ
10 Mar 2026
Identify the correct order of organisation of genetic material from largest to smallest :
A.
Chromosome, genome, nucleotide, gene
B.
Genome, chromosome, nucleotide, gene
C.
Genome, chromosome, gene, nucleotide
D.
Chromosome, gene, genome, nucleotide
2015 Q102 NEET MCQ
10 Mar 2026
Gene regulation governing lactose operon of E.coli that involves the lac I gene product is
A.
negative and inducible because repressor protein prevents transcription.
B.
positive and inducible because it can be induced by lactose
C.
negative and repressible because repressor protein prevents transcription
D.
feedback inhibition because excess of $\beta $-galactosidase can switch off transcription
2015 Q103 NEET MCQ
10 Mar 2026
In sea urchin DNA, which is double stranded, 17% of the bases were shown to be cytosine, The percentages of the other three bases expected to be present in this DNA are
A.
G 17%, A 16.5%, T 32.5%
B.
G 17%, A 33%, T 33%
C.
G 8.5%, A 50%, T 24.5%
D.
G 34%, A 24.5%, T 24.5%
2014 Q104 NEET MCQ
10 Mar 2026
Transformation was discovered by :
A.
Griffith
B.
Watson and Crick
C.
Hershey and Chase
D.
Meselson and Stahl
2014 Q105 NEET MCQ
10 Mar 2026
Select the correct option ;
A.
Direction of RNA synthesis 3’−5’, Direction of reading of the template DNA strand 5’−3’
B.
Direction of RNA synthesis 5’−3’, Direction of reading of the template DNA strand 5’−3’
C.
Direction of RNA synthesis 5’−3’, Direction of reading of the template DNA strand 3’−5’
D.
Direction of RNA synthesis 3’−5’, Direction of reading of the template DNA strand 3’−5’
2014 Q106 NEET MSQ
10 Mar 2026
Which one of the following is wrongly matched?
A.
Transcription − Writing information from DNA to t−RNA
B.
Operon − Structural genes, operator and promoter
C.
Repressor protein − Binds to operator to stop enzyme synthesis
D.
Translation − Using information in m−RNA to make protein.
2013 Q107 NEET MCQ
10 Mar 2026
One of the most frequently used techniques in DNA fingerprinting is :-
A.
SSCP
B.
SCAR
C.
VNTR
D.
AFLP
2013 Q108 NEET MCQ
10 Mar 2026
NEET 2013 (Karnataka) Biology - Molecular Basis of Inheritance Question 156 English The figure gives an important concept in the genetic implication of DNA . Fill the blanks A, B and C.
A.
A - Erwin Chargaff
B - translation
C - replication
B.
A - Maurice Wilkins
B - transcription
C - translation
C.
A - Francis Crick
B - translation
C - transcription
D.
A - James Watson
B - replication
C - extension
2013 Q109 NEET MCQ
10 Mar 2026
Which of the following is not a property of the genetic code ?
A.
Ambiguous
B.
Universal
C.
Degeneracy
D.
Non-overlapping
2013 Q110 NEET MCQ
10 Mar 2026
Satellite RNA are present in some :
A.
Prions
B.
Bacteriophages
C.
Plant viruses
D.
Viroids
2013 Q111 NEET MCQ
10 Mar 2026
Genes of interest can be selected from a genomic library by using :
A.
Restriction enzymes
B.
Gene targets
C.
Cloning vectors
D.
DNA probes
2013 Q112 NEET MCQ
10 Mar 2026
In an inducible operon, the genes are :
A.
usually expressed unless a signal turns them "off"
B.
always expressed
C.
never expressed
D.
usually not expressed unless a signal turns them "on"
2013 Q113 NEET MCQ
10 Mar 2026
Which of the following statements is not true of two genes that show 50% recombination frequency ?
A.
The genes are tightly linked
B.
The genes show independent assortment
C.
If the genes are present on the same chromosome, they undergo more than one crossovers in every meiosis.
D.
The genes may be on different chromosomes
2013 Q114 NEET MCQ
10 Mar 2026
The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C. NEET 2013 Biology - Molecular Basis of Inheritance Question 158 English
A.
A-translation B-extension C-Rosalind Franklin
B.
A-translation B-transcription C-Erevin Chargaff
C.
A-transcription B-translation C-Francis Crick
D.
A-transcription B-replication C-James Watson
2013 Q115 NEET MCQ
10 Mar 2026
Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?
A.
Transacetylase
B.
Lactose permease and transacetylase
C.
Lactose permease
D.
$\beta $-galactosidase
2012 Q116 NEET MCQ
10 Mar 2026
Read the following four statements (A-D) :
(A) In transcription, adenosine pairs with uracil
(B) Regulation of lac operon by repressor is referred to as positive regulation
(C) The human genome has approximately 50,000 genes
(D) Haemophilia is a sex-linked recessive disease
How many of the above statements are right ?
A.
Four
B.
Two
C.
Three
D.
One
2012 Q117 NEET MCQ
10 Mar 2026
Removal of introns and joining of exons in a defined order during transcription is called
A.
Looping
B.
Inducing
C.
Slicing
D.
Splicing
2012 Q118 NEET MCQ
10 Mar 2026
Which one of the following is not a part of a transcription unit in DNA ?
A.
The structural gene
B.
the inducer
C.
A terminator
D.
A promoter
2012 Q119 NEET MCQ
10 Mar 2026
Ribosomal RNA is actively synthesized in
A.
Nucleolus
B.
Ribosomes
C.
Lysosomes
D.
Nucleoplasm
2012 Q120 NEET MCQ
10 Mar 2026
If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA stand sequence
A.
ATCGU
B.
UAGAC
C.
AACTG
D.
TTAGU
2012 Q121 NEET MCQ
10 Mar 2026
Removal of RNA polymerase -III from nucleoplasm will affect the synthesis of
A.
tRNA
B.
hnRNA
C.
rRNA
D.
mRNA
2011 Q122 NEET MCQ
10 Mar 2026
The unequivocal proof of DNA as the genetic material came from the studies on a :
A.
Viroid
B.
Bacterium
C.
Fungus
D.
Bacterial virus
2011 Q123 NEET MCQ
10 Mar 2026
What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope ?
A.
Nucleosomes
B.
Genes
C.
Nucleotides
D.
Base pairs
2010 Q124 NEET MCQ
10 Mar 2026
The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join -
A.
One nucleotide with another nucleotide
B.
One nitrogenous base with pentose sugar
C.
One nucleoside with another nucleoside
D.
One DNA strand with the other DNA strand
2010 Q125 NEET MCQ
10 Mar 2026
In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the -
A.
Dictyosomes
B.
Ribosomes
C.
Nucleus
D.
ER
2010 Q126 NEET MCQ
10 Mar 2026
Which one of the follwoing statements about the particular entity is true ?
A.
Nucleosome is formed of nucleotides
B.
Centromere is found in animals cells, which produces aster during cell division
C.
The gene for producing insulin is present in every body cell
D.
DNA consists of a core of eight histones
2010 Q127 NEET MCQ
10 Mar 2026
The lac Operon consists of -
A.
Three regulatory genes and three structure genes
B.
Four regulatory genes only
C.
Two regulatory genes and two structural genes
D.
One regulatory gene and three structural genes
2010 Q128 NEET MCQ
10 Mar 2026
Select the two correct statements out of the four (a-d) statements given below about lac operon.
(a) Glucose or galactose may bind with the repressor and inactivate it
(b) In the absence of lactose the repressor binds with the operator region
(c) The z-gene codes for permease
(d) This was elucidated by Francois Jacob and Jacque Monod
The correct statements are :
A.
(b) and (d)
B.
(a) and (b)
C.
(b) and (c)
D.
(a) and (c)
2010 Q129 NEET MCQ
10 Mar 2026
Which one of the following does not follow the central dogma of molecular biology ?
A.
Mucor
B.
HIV
C.
Chlamydomonas
D.
Pea
2010 Q130 NEET MCQ
10 Mar 2026
The one aspect which is not a salient feature of genetic code, is its being –
A.
Specific
B.
Degenerate
C.
Ambiguous
D.
Universal
2010 Q131 NEET MCQ
10 Mar 2026
Which one of the following palindromic base sequences in DNA can be easily cut at about the middle by some particular restriction enzyme?
A.
5' _____ CG TTCG ______ 3'
3' ______ATGGTA ______5'
B.
5'______GAATTC ______3'
3'______CTTAAG______5'
C.
5'______CACGTA______3'
3'______CTCAGT______5'
D.
5'______GATATG ______3'
3'______CTACTA ______5'
2009 Q132 NEET MCQ
10 Mar 2026
Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet" ?
A.
Nirenberg and Mathaei
B.
Morgan and Sturtevant
C.
Hershey and Chase
D.
Beadle and Tatum
2009 Q133 NEET MCQ
10 Mar 2026
Removal of introns and joining the exons in a defined order in a transcription unit is called :
A.
Transformation
B.
Capping
C.
Splicing
D.
Tailing
2009 Q134 NEET MCQ
10 Mar 2026
What is not true for genetic code?
A.
It is nearly universal
B.
A codon in mRNA is read in a noncontiguous fashion
C.
It is degenerate
D.
It is unambiguous
2009 Q135 NEET MCQ
10 Mar 2026
Semi-conservative replication of DNA was first demonstrated in :
A.
Drosophila melanogaster
B.
Streptococcus pneumoniae
C.
Salmonella typhimurium
D.
Escherichia coli
2008 Q136 NEET MCQ
10 Mar 2026
Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?
A.
Thymine, Uracil — Pyrimidines
B.
Guanine, Adenine — Purines
C.
Uracil, Cytosine — Pyrimidines
D.
Adenine, Thymine — Purines
2008 Q137 NEET MCQ
10 Mar 2026
Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?
A.
UUA, UCA — Leucine
B.
AUG, ACG — Start/Methionine
C.
UAG, UGA — Stop
D.
GUU, GCU — Alanine
2008 Q138 NEET MCQ
10 Mar 2026
Polysome is formed by
A.
several ribosomes attached to a single mRNA
B.
many ribosomes attached to a strand of endoplasmic reticulum
C.
a ribosome with several subunits
D.
ribosomes attached to each other in a linear arrangement
2008 Q139 NEET MCQ
10 Mar 2026
In the DNA molecule:
A.
the total amount of purine nucleotides and pyrimidine nucleotides is not always equal
B.
there are two strands which run antiparallel one in 5'→ 3' direction and other in 3'→ 5'
C.
there are two strands which run parallel in the 5'→ 3' direction
D.
the proportion of adenine in relation to thymine varies with the organism
2006 Q140 NEET MCQ
10 Mar 2026
Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis ?
A.
Neomycin
B.
Erythromycin
C.
Tetracycline
D.
Streptomycin
2006 Q141 NEET MCQ
10 Mar 2026
Antiparallel strands of a DNA molecule means that-
A.
The phosphate groups at the start of two DNA strands are in opposite position (pole)
B.
One strand turns anti-clockwise
C.
One strand turns clockwise
D.
The phosphate groups of two DNA stands, at their ends, share the same position
2006 Q142 NEET MCQ
10 Mar 2026
Amino acid sequence, in protein synthesis is decided by the sequence of -
A.
cDNA
B.
mRNA
C.
tRNA
D.
rRNA
2006 Q143 NEET MCQ
10 Mar 2026
One gene-one enzyme hypothesis was postulated by -
A.
A.Garrod
B.
Hershey and Chase
C.
Beadle and Tatum
D.
R. Franklin
2006 Q144 NEET MCQ
10 Mar 2026
One turn of the helix in a B-form DNA is approximately -
A.
20 nm
B.
3.4 nm
C.
2 nm
D.
0.34 nm
2005 Q145 NEET MCQ
10 Mar 2026
Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?
A.
protease
B.
Endonuclease
C.
Lipase
D.
Exonuclease
2005 Q146 NEET MCQ
10 Mar 2026
Telomerase is an enzyme which is a -
A.
RNA
B.
Repetitive DNA
C.
Simple protein
D.
Ribonucleoprotein
2005 Q147 NEET MCQ
10 Mar 2026
Using imprints from a plate with complete medium and carrying bacterial colonies, you can select streptomycin resistant mutants and prove that such mutations do not originates as adaptation. These imprints need to be used -
A.
On plates with minimal medium
B.
Only on plates with streptomycin
C.
Only on plates without streptomycin
D.
On plates with and without streptomycin
2005 Q148 NEET MCQ
10 Mar 2026
Which one of the following makes use of RNA as a template to synthesize DNA -
A.
Reverse transcriptase
B.
DNA dependant RNA polymerase
C.
RNA polymerase
D.
DNA polymerase
2005 Q149 NEET MCQ
10 Mar 2026
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called ?
A.
TATA box
B.
GGTT box
C.
CAAT box
D.
AAAT box
2005 Q150 NEET MCQ
10 Mar 2026
Protein synthesis in an animal cell occurs -
A.
On ribosomes present in the nucleolus as well as in cytoplasm
B.
On ribosomes presents in cytoplasm as well as in mitochondria
C.
Only on the ribosomes present in cytosol
D.
Only on ribosomes attached to the nuclear envelope and endoplasmic reticulum