1990
Q1
Allen
PYQ
MCQ
Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency ?
A.
Immunotherapy
B.
Radiation therapy
C.
Gene therapy
D.
Chemotherapy
1984
Q2
Allen
NCERT BASED QUESTIONS
MCQ
The first clinical gene therapy was given to a 4-year old girl with ADA deficiency in :-
A.
1984
B.
1986
C.
1992
D.
1990
1968
Q3
Allen
NCERT BASED QUESTIONS
MCQ
First recombinant DNA was made by Stanley Cohen and Herbert Boyer in :-
A.
1968
B.
1970
C.
1972
D.
1974
1963
Q4
Allen
NCERT BASED QUESTIONS
MCQ
The enzymes responsible for restricting the growth of bacteriophage in E coli were isolated in 1963, these enzyme are :-
A.
DNA ligases
B.
Alkaline phosphatases
C.
DNA polymerases
D.
Restriction endonuclease
1963
Q5
Allen
NCERT BASED QUESTIONS
MCQ
Two enzymes responsible for restricting the growth of bacteriophage in E. coli were isolated in 1963, one of these cut DNA, while other :-
A.
Add propyl group to DNA
B.
Add ethyl group to DNA
C.
Add methyl group to DNA
D.
None of the above
Q6
Allen
PRINCIPLES AND PROCESSES
MCQ
Agrobacterium tumefaciens used in Genetic engineering is for :-
A.
DNA-mapping
B.
DNA-modification
C.
Gene transfer
D.
DNA finger printing
Q7
Allen
PRINCIPLES AND PROCESSES
MCQ
Who isolated the first restriction endonucleases?
A.
Temin & Baltimore
B.
Sanger
C.
Smith
D.
Paul berg
Q8
Allen
PRINCIPLES AND PROCESSES
MCQ
Genetic engineering is :-
A.
Study of extra nuclear gene
B.
Manipulation of genotype by artificial method
C.
Manipulation of RNA
D.
Manipulation of enzymes
Q9
Allen
PRINCIPLES AND PROCESSES
MCQ
Polymerase chain reaction technology ("PCR"-technique) is used for :-
A.
DNA identification
B.
DNA repair
C.
DNA amplification
D.
Cleave DNA
Q10
Allen
PRINCIPLES AND PROCESSES
MCQ
Which structure involved in genetic engineering?
A.
Plastid
B.
Plasmid
C.
Codon
D.
None
Q11
Allen
PRINCIPLES AND PROCESSES
MCQ
Which of the following is the example of chemical scissors?
A.
Eco - RI
B.
Hind - III
C.
Bam - I
D.
All the above
Q12
Allen
PRINCIPLES AND PROCESSES
MCQ
Restriction endonucleases are used in genetic engineering because:-
A.
They can degrade harmful proteins
B.
They can join DNA fragments
C.
They can cut DNA at variable site
D.
They can cut DNA at specific base sequences
Q13
Allen
PRINCIPLES AND PROCESSES
MCQ
When the genotype of an organism is improved by the addition of foreign gene, the process is called :-
A.
Tissue culture
B.
Genetic diversity
C.
Genetic engineering
D.
Plastic surgery
Q14
Allen
PRINCIPLES AND PROCESSES
MCQ
A genetically manipulated organism containing in its genome one or more inserted gene of another species is called :-
A.
Transposon
B.
Gene expression
C.
Transgenic organism
D.
Retroposons
Q15
Allen
PRINCIPLES AND PROCESSES
MCQ
Which vector is commonly used in the transfer of gene in a crop plant?
A.
Plasmids of B. Subtilis
B.
Bacteriophages
C.
Ti-plasmids of Agrobacterium
D.
E. coli Phages
Q16
Allen
PRINCIPLES AND PROCESSES
MCQ
The tumour inducing capacity of Agrobacterium tumefaciens is located in extrachromosomal
plasmid and called:-
A.
Ti ā plasmid
B.
Ri - plasmid
C.
Lambda phage
D.
Plasmid $p_{BR}$ 322
Q17
Allen
PRINCIPLES AND PROCESSES
MCQ
Genetic engineering aims at :-
A.
Destroying wild gene
B.
Preserving defective gene
C.
Curing human disease by introducing new gene
D.
All the above
Q18
Allen
PRINCIPLES AND PROCESSES
MCQ
A piece of nucleic acid using to find out a gene, by forming hybrid with it, is called as:-
A.
c ā DNA
B.
DNA probe
C.
Sticky end
D.
Blunt end
Q19
Allen
PRINCIPLES AND PROCESSES
MCQ
Taq - polymerase which is used for amplification of DNA is related with:-
A.
Hybridoma technique
B.
""-technique
C.
Gene cloning
D.
r-DNA technology
Q20
Allen
PRINCIPLES AND PROCESSES
MCQ
What is true for plasmid?
A.
Plasmids are widely used in gene transfer
B.
These are found in virus
C.
Plasmid contains gene for vital activities
D.
These are main part of chromosome
Q21
Allen
PRINCIPLES AND PROCESSES
MCQ
Which of the following cuts the DNA from specific places?
A.
Restriction endonuclease
B.
Ligase
C.
Exonuclease
D.
Alkaline phosphatase
Q22
Allen
PRINCIPLES AND PROCESSES
MCQ
Manipulation of DNA in genetic engineering became possible due to the discovery of:-
A.
Restriction endonuclease
B.
DNA ligase
C.
Transcriptase
D.
Primase
Q23
Allen
PRINCIPLES AND PROCESSES
MCQ
Which one of the following has found extensive use in genetic engineering work in plants?
A.
Bacillus coagulens
B.
Agrobacterium tumefaciens.
C.
Clostridium septicum
D.
Xanthomonas citri
Q24
Allen
PRINCIPLES AND PROCESSES
MCQ
Restriction endonucleases: -
A.
Are enzymes which cleave DNA at specific sites
B.
Make DNA complementary to an existing DNA or RNA
C.
Cut or join DNA fragments
D.
Are required in vectorless direct gene transfer.
Q25
Allen
PRINCIPLES AND PROCESSES
MCQ
Restriction endonucleases :-
A.
Are synthesized by bacteria as part of their defense mechanism
B.
Are present in mammalian cells for degradation of DNA when the cell dies
C.
Are used in genetic engineering for ligating two DNA molecules
D.
Are used for invitro DNA synthesis