Principles of Inheritance and Variation

175 Questions Start NEET Test
2011 Q101 NEET MCQ
10 Mar 2026
Which one of the following conditions of the zygotic cell would lead to the birth of a normal human female child ?
A.
only one Y chromosome
B.
only one X chromosome
C.
one X and one Y chromosome
D.
two X chromosomes
2011 Q102 NEET MCQ
10 Mar 2026
Which one of the following conditions correctly describes the manner of determining the sex ?
A.
XO condition in humans as found in Turner Syndrome, determines female sex
B.
XO type of sex chromosomes determine male sex in grasshopper
C.
Homozygous sex chromosomes (ZZ) determine female sex in Birds
D.
Homozygous sex chromosomes (XX) produce male in Drosophila
2011 Q103 NEET MCQ
10 Mar 2026
Mutations can be induced with :
A.
Gamma radiation
B.
Infra Red radiations
C.
IAA
D.
Ethylene
2011 Q104 NEET MCQ
10 Mar 2026
When two unrelated individuals or lines are crossed, the per romance of F1 hybrid is often superior to both parents. This phenomenon is called :
A.
Sphcing
B.
Transformation
C.
Heterosis
D.
Metamorphosis
2010 Q105 NEET MCQ
10 Mar 2026
Study the pedigree chart of a certain family given below and select the correct conculusion which can be drawn for the character – AIPMT 2010 Mains Biology - Principles of Inheritance and Variation Question 133 English
A.
The trait under study could not be colourblindness
B.
The female parent is heterozygous
C.
The parents could not have had a normal daughter for this character
D.
The male parent is homozygous dominant
2010 Q106 NEET MCQ
10 Mar 2026
ABO blood grouping is controlled by gene I which has three alleles and show co-dominance. There are six genotypes. How many phenotypes in all are possible -
A.
five
B.
four
C.
three
D.
six
2010 Q107 NEET MCQ
10 Mar 2026
A cross in which an organism showing a dominant phenotype in crossed with the recessive parent in order to know its genotype is called -
A.
Dihybrid cross
B.
Back cross
C.
Monohybrid cross
D.
Test cross
2010 Q108 NEET MCQ
10 Mar 2026
In antirrhinum two plants with pink flowers were hybridized. The F1 plants produced red, pink and white flowers in the proportion of 1 red, 2 pink and 1 white. What could be the genotype of the two plants used for hybridization ? Red flower colour is determined by RR, and White by rr genes -
A.
rrrr
B.
rr
C.
Rr
D.
RR
2010 Q109 NEET MCQ
10 Mar 2026
ABO blood groups in humans are controlled by the gene I. It has three alleles – IA, IB and i. Since there are three different alleles, six different genotypes are possible. How many phenotypes can occur –
A.
One
B.
Two
C.
Three
D.
Four
2010 Q110 NEET MCQ
10 Mar 2026
Which one of the following cannot be explained on the basis of Mendel's Law of Dominance?
A.
Out of one pair of factors one is dominant, and the other recessive
B.
Alleles do not show any blending and both the characters recover as such in F2 generation
C.
The discrete unit controlling a particular character is called a factor
D.
Factors occur in pairs
2010 Q111 NEET MCQ
10 Mar 2026
The genotype of a plant showing the dominant phenotype can be determined by –
A.
Pedigree analysis
B.
Back cross
C.
Test cross
D.
Dihybrid cross
2010 Q112 NEET MCQ
10 Mar 2026
Select the correct statement from the ones given below with respect to dihybrid cross –
A.
Genes far apart on the same chromosome show very few recombinations
B.
Tightly linked genes on the same chromosome show very few recombination
C.
Tightly linked genes on the same chromosome show higher recombinations
D.
Genes loosely linked on the same chromosome show similar recombinations as the tightly linked ones
2010 Q113 NEET MCQ
10 Mar 2026
Which one of the following symbols and its representation, used in human pedigree analysis is correct –
A.
AIPMT 2010 Prelims Biology - Principles of Inheritance and Variation Question 139 English Option 1
B.
AIPMT 2010 Prelims Biology - Principles of Inheritance and Variation Question 139 English Option 2
C.
AIPMT 2010 Prelims Biology - Principles of Inheritance and Variation Question 139 English Option 3
D.
AIPMT 2010 Prelims Biology - Principles of Inheritance and Variation Question 139 English Option 4
2009 Q114 NEET MCQ
10 Mar 2026
Select the incorrect statement from the following :
A.
Baldness is a sex limited trait
B.
Galactosemia is an inborn error of metabolism
C.
Linkage is an exception to the principle of independent assortment in heredity.
D.
Small population size results in random genetic drift in a population
2009 Q115 NEET MCQ
10 Mar 2026
The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because "O" in it refers to having :
A.
Other antigens besides A and B on RBCs
B.
No antigens A and B on RBCs
C.
Overdominance of this type on the genes for A and B types
D.
One antibody only-either anti-A and anti-B on the RBCs
2009 Q116 NEET MCQ
10 Mar 2026
Study the pedigree chart given below : AIPMT 2009 Biology - Principles of Inheritance and Variation Question 126 English What does it show ?
A.
Inheritance of a recessive sex-linked disease like haemophilia
B.
Inheritance of a sex-linked inborn error of metabolism like phenylketonuria
C.
The pedigree chart is wrong as this is not possible
D.
Inheritance of a condition like phenylketonuria as an autosomal recessive trait
2009 Q117 NEET MCQ
10 Mar 2026
The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by
A.
Introducing bone marrow cells producing ADA into cells at early embryonic stages
B.
Periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
C.
Administering adenosine deaminase activators
D.
Enzyme replacement therapy
2009 Q118 NEET MCQ
10 Mar 2026
Sickle-cell anemia is :
A.
Caused by substitute of valine by glutamic acid in the beta globin chain of haemoglobin
B.
An autosomal linked dominant trait
C.
Caused by a change in a single base pair of DNA
D.
Characterized by elongated sickle like RBCs with a nucleus
2008 Q119 NEET MCQ
10 Mar 2026
Which one of the following conditions in humans is correctly matched with its chromosomal abnormality/linkage?
A.
Klinfelter's syndrome — 44 autosomes + XXY
B.
Colour-blindness — Y-linked
C.
Down syndrome — 44 autosomes + XO
D.
Erythroblastosis foetalis — X-linked
2008 Q120 NEET MCQ
10 Mar 2026
Haploids are more suitable for mutation studies than the diploids. This is because:
A.
all mutations, whether dominant or recessive are expressed in haploids
B.
mutagens penetrate in haploids more effectively than in diploids
C.
haploids are reproductively more stable than diploids
D.
haploids are more abundant in nature than diploids
2007 Q121 NEET MCQ
10 Mar 2026
A common test to find the genotype of a hybrid is by:-
A.
Crossing of one F1 progeny with male parent
B.
Crossing of one F2 progeny with female parent
C.
Crossing of one F2 progeny with male parent
D.
Studying the sexual behaviour of F1 progenies
2007 Q122 NEET MCQ
10 Mar 2026
A human male produces sperms with the genotypes AB, Ab, AB, and ab pertaining to two diallelic characters in equal proportions. What is the corresponding genotype of this person ?
A.
AaBb
B.
AABB
C.
AaBB
D.
AABb
2007 Q123 NEET MCQ
10 Mar 2026
In the hexaploid wheat, the haploid(n) and basic(x) numbers of chromosomes are :
A.
n = 21 and x = 14
B.
n = 21 and x = 21
C.
n = 7 and x = 21
D.
n = 21 and x = 7
2007 Q124 NEET MCQ
10 Mar 2026
Inheritance of skin colour in humans is an example of:-
A.
Chromosomal aberration
B.
Polygenic inheritance
C.
Codominance
D.
Point mutation
2007 Q125 NEET MCQ
10 Mar 2026
In pea plants, yellow seeds are dominant to green. If a heterozygous yellow seeded plant is crossed with a green seeded plant, what ratio of yellow and green seeded plants would you expect in F1 generation ?
A.
9 : 1
B.
3 : 1
C.
50 : 50
D.
1 : 3
2006 Q126 NEET MCQ
10 Mar 2026
Sickle cell anaemia has not been eliminated from the African population because-
A.
It is not a fatal disease
B.
It is controlled by dominant genes
C.
It is controlled by recessive genes
D.
It provides immunity against malaria
2006 Q127 NEET MCQ
10 Mar 2026
Test cross involves-
A.
Crossing between two F1 hybrids
B.
Crossing the F1 hybrid with a double recessive genotype
C.
Crossing between two genotypes with recessive trait
D.
Crossing between two genotypes with dominant trait
2006 Q128 NEET MCQ
10 Mar 2026
In Mendel's experiments with garden pea, round seed shape (RR) was dominant over wrinkled seeds (rr), yellow cotyledon (YY) was dominant over green cotyledon (yy). What are the expected phenotypes in the F2 generation of the cross RRYY × rryy ?
A.
Round seeds with yellow cotyledons, and wrinkled seeds with yellow cotyledons
B.
Only wrinkled seeds with green cotyledons
C.
Only wrinkled seeds with yellow cotyledons
D.
Only round seeds with green cotyledons
2006 Q129 NEET MCQ
10 Mar 2026
How many different kinds of gametes will be produced by a plant having the genotype AABbCC ?
A.
Two
B.
Nine
C.
Four
D.
Three
2006 Q130 NEET MCQ
10 Mar 2026
Phenotype of an organism is the result of-
A.
Environmental changes and sexual dimorphism
B.
Cytoplasmic effects and nutrition
C.
Genotype and environment interactions
D.
Mutations and linkages
2006 Q131 NEET MCQ
10 Mar 2026
If a colour blind woman marries a normal visioned man, their sons will be
A.
All normal visioned
B.
Three-fourths colourblind and one-fourth normal
C.
One-half colourblind and one-half normal
D.
All colourblind
2006 Q132 NEET MCQ
10 Mar 2026
Which one of the following is an example of polygenic inheritance ?
A.
Skin colour in humans
B.
Pod shape in garden pea
C.
Production of male honey bee
D.
Flower colour in Mirabilis jalapa
2006 Q133 NEET MCQ
10 Mar 2026
Both sickle cell anemia and Huntington's chorea are-
A.
Congenital disorders
B.
Bacteria-related diseases
C.
Virus-related diseases
D.
Pollutant-induced disorders
2006 Q134 NEET MCQ
10 Mar 2026
Cri-du-chat syndrome in humans is caused by the-
A.
Loss of half of the long arm of chromosome 5
B.
Loss of half of the short arm of chromosome 5
C.
Trisomy of 21st chromosome
D.
Fertilization of an XX egg by a normal Y-bearing sperm
2005 Q135 NEET MCQ
10 Mar 2026
G-6-P dehydrogenase deficiency is associated with haemolysis of -
A.
RBCs
B.
Lymphocytes
C.
Platelets
D.
Leucocytes
2005 Q136 NEET MCQ
10 Mar 2026
Which of the following is not a hereditary disease ?
A.
Cretinism
B.
Cystic fibrosis
C.
Haemophilia
D.
Thalasasemia
2005 Q137 NEET MCQ
10 Mar 2026
A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 daughter and 5 sons). Three of the sons suffer from the given disease but none of the daughters are affected. Which of the following mode of inheritance do you suggest for this disease
A.
Autosomal dominant
B.
Sex-linked recessive
C.
Sex-linked dominant
D.
Sex-limited recessive
2005 Q138 NEET MCQ
10 Mar 2026
A women with 47 chromosomes due to three copies of chromosome 21 is characterized by -
A.
Superfemaleness
B.
Turner's syndrome
C.
Triploidy
D.
Down's syndrome
2005 Q139 NEET MCQ
10 Mar 2026
A women with 47 chromosomes due to three copies of chromosome 21 is characterized by
A.
triploidy
B.
Down’s syndrome
C.
superfemaleness
D.
Turner’s syndrome
2005 Q140 NEET MCQ
10 Mar 2026
A woman with normal vision, but whose father was colour bind, marries a colour blind man. Suppose that the fourth child of this couple was a boy. This boy -
A.
May be colour blind or may be normal vision
B.
Must have normal colour vision
C.
Must be colour blind
D.
Will be partially colour blind since he is heterozygous for the colour blind mutant allele.
2005 Q141 NEET MCQ
10 Mar 2026
Haemophilia is more commonly seen in human males than in human females because -
A.
This disease is due to an X-linked dominant mutation
B.
This disease is due to a Y-linked recessive mutation
C.
This disease is due to an X-linked recessive mutation
D.
A greater proportion of girls die in infancy
2005 Q142 NEET MCQ
10 Mar 2026
In order to find out the different types of gametes produced by a pea plants having the genotype AaBb, it should be crossed to a plant with the genotype -
A.
aaBB
B.
aabb
C.
AaBb
D.
AABB
2004 Q143 NEET MCQ
10 Mar 2026
One of the parents of a cross has a mutation in its mitochondria. In that cross, that parent is taken as a male. During segregation of F2 progenies that mutation is found in -
A.
50% of the progenies
B.
1/3 of the progenies
C.
None of the progenies
D.
All the progenies
2004 Q144 NEET MCQ
10 Mar 2026
The recessive genes located on X-chromosomes in humans are always-
A.
Expressed in females
B.
Sub-lethal
C.
Expressed in males
D.
Lethal
2004 Q145 NEET MCQ
10 Mar 2026
A male human is heterozygous for autosomal genes A and B and is also hemizygous for hemophilic gene h. What proportion of his sperms will be abh :-
A.
1/16
B.
1/32
C.
1/8
D.
1/4
2004 Q146 NEET MCQ
10 Mar 2026
A normal woman, whose father was colour-blind is married to a normal man. The sons would be :-
A.
All colour-blind
B.
75 % colour-blind
C.
All normal
D.
50% colour-blind
2004 Q147 NEET MCQ
10 Mar 2026
Lack of independent assortment of two genes A and B in fruit fly Drosophila is due to :-
A.
Linkage
B.
Recombination
C.
Repulsion
D.
Crossing over
2004 Q148 NEET MCQ
10 Mar 2026
In a plant, red fruit (R) is dominant over yellow fruit (r) and tallness (T) is dominant over shortness (t). If a plant with RRTt genotype is crossed with a plant that is rrtt
A.
75% will be tall with red fruit
B.
25% will be tall with red fruit
C.
50% will be tall with red fruit
D.
All the offspring will be tall with red fruit
2003 Q149 NEET MCQ
10 Mar 2026
Which one of the following conditions though harmful in itself, is also a potential saviour from a mosquito borne infectious disease ?
A.
Pernicius anaemia
B.
Thalassaemia
C.
Leukemia
D.
Sickle cell anaemia
2003 Q150 NEET MCQ
10 Mar 2026
Down's syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder ?
A.
50%
B.
100%
C.
75%
D.
25%