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NEET
1 1. Short-Distance Transport Mechanisms
Short-distance transport involves the movement of molecules and ions across cell membranes through both passive (no energy required) and active (energy required) processes. According to the sources, these mechanisms are summarized below:
1. Passive Transport
Passive transport is the movement of substances along or down a concentration gradient (from high to low concentration) and does not require metabolic energy.
- Diffusion: This is the spontaneous movement of ions or molecules. The rate of diffusion increases at higher temperatures because of the increased kinetic activity of the particles.
- Facilitated Diffusion (Facilitated Transport): This involves the passage of molecules or ions across a membrane through specific transmembrane integral proteins (carrier proteins or channels).
- Selectivity: Most transport proteins are highly selective, allowing only specific molecules to pass.
- Saturation: This process can reach "transport saturation" when all available protein carriers are in use.
- Nature: It is still a "downhill" process and does not require ATP. Hydrophilic substances often require this method because they face difficulty passing through the non-polar, hydrophobic lipid bilayer of the cell membrane.
- Osmosis: The specific diffusion of water across a membrane. Water moves from an area of high water potential (hypotonic solution) to an area of low water potential.
2. Active Transport
Active transport is the movement and accumulation of ions or molecules against their concentration gradient (from lower to higher concentration).
- Energy Requirement: This process is "uphill" and requires an additional input of energy, primarily from the hydrolysis of ATP.
- Selectivity: Active transport is highly selective for particular ions, utilizing specific channels like sodium/potassium or calcium channels.
- Types:
- Primary Active Transport: Uses ATP directly.
- Secondary Active Transport: Uses an electrochemical gradient.
3. Directional Movement (Cotransport)
When carrier proteins facilitate the movement of molecules, the process is categorized by the direction of the substances involved:
- Symport: Two different molecules move across the membrane in the same direction using the same carrier protein.
- Antiport: Two molecules move in opposite directions using the same carrier.
- Uniport: A single molecule moves across the membrane.
4. Key Formulas for Cell Water Relations
Short-distance movement, especially of water (osmosis), is governed by the following formulas:
-
Diffusion Pressure Deficit (DPD): This determines the direction of water movement between contiguous cells. Water always moves from a cell with lower DPD to higher DPD. $$\mathbf{DPD = OP - TP}$$ (Where OP = Osmotic Pressure and TP = Turgor Pressure).
-
Water Potential ($\Psi_w$): Defined as the difference between the chemical potential of water in a system and that of pure water. $$\mathbf{\Psi_w = \Psi_s + \Psi_p}$$ (Where $\Psi_s = $ Solute Potential (always negative) and $\Psi_p = $ Pressure Potential (usually positive)).
-
State of Pure Water: The water potential and osmotic potential of pure water are both zero. Adding solutes lowers the free energy of water, making the water potential negative.
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PYQ for: 1. Short-Distance Transport Mechanisms
Question 1
Question: Movement and accumulation of ions across a membrane against their concentration gradient can be explained by
Options:
A. Facilitated Diffusion
B. Passive Transport
C. Active Transport
D. Osmosis
Correct Answer: C
Year: [NEET 2023]
Solution: Movement and accumulation of ions across a membrane against their concentration gradient can be explained by active transport. It uses energy to transport molecules from lower concentration to a higher concentration.
Step Solution:
1. Observe the direction of ion movement: "against their concentration gradient."
2. Recall that moving substances "uphill" from low to high concentration requires metabolic energy.
3. Identify the transport mechanisms: Passive transport (Diffusion, Osmosis, Facilitated Diffusion) always moves substances "downhill" (along a gradient).
4. Conclusion: Only Active Transport utilizes ATP energy to move ions against a gradient.
The difficulty level: Easy
The Concept Name: Active Transport
Short cut solution: Against gradient + Energy required = Active Transport.
Question 5
Question: During symport two different molecules move across the membrane :
Options:
A. in same direction with the help of different carriers located at a common site
B. in same direction with the help of different carriers located at different sites in the same cell
C. in same direction with the help of same carrier
D. in opposite direction with the help of same carrier
Correct Answer: C
Year: [NEET 2023 mpr]
Solution: Symport is a type of transport mechanism that occurs in a cell's membrane. In symport, two different molecules or ions are transported across the membrane in the same direction, but they are co-transported by the same carrier protein.
Step Solution:
1. Define the prefix "sym-", which means "together" or "same."
2. Identify the number of molecules involved: Two different molecules.
3. Determine the direction: Same direction.
4. Identify the vehicle: A single/same carrier protein facilitates the move.
The difficulty level: Easy
The Concept Name: Symport (Cotransport)
Short cut solution: Sym = Same direction; Anti = Opposite direction.
Question 7
Question: When a carrier protein facilitates the movement of two molecules across the membrane in same direction, it is called :
Options:
A. Symport
B. Uniport
C. Transport
D. Antiport
Correct Answer: A
Year: [NEET Re-2022]
Solution: Symport is the type of transportation where the two molecules move simultaneously in the same direction using carrier protein.
Step Solution:
1. Analyze the query: Two molecules moving in the same direction.
2. Differentiate terms: Uniport (one molecule), Antiport (two molecules, opposite directions).
3. Select the term corresponding to "same direction" movement for two molecules.
The difficulty level: Easy
The Concept Name: Membrane Transport (Symport)
Short cut solution: 2 molecules + Same direction = Symport.
Question 9
Question: Which type of substance would face difficulty to pass through the cell membrane?
Options:
A. Substance soluble in lipids
B. Substance with hydrophobic moiety
C. Substance with hydrophilic moiety
D. All substance irrespective of hydrophobic and hydrophilic moiety
Correct Answer: C
Year: [NEET Re-2022]
Solution: (The source lists C as the answer). Hydrophilic substances (water-loving) have difficulty passing through the non-polar, hydrophobic lipid bilayer of the cell membrane.
Step Solution:
1. Identify the composition of the cell membrane: Primarily a lipid bilayer.
2. Recall the property of lipids: They are hydrophobic (non-polar).
3. Identify the property of the substance: Hydrophilic (polar/water-loving).
4. Apply "like dissolves like": Hydrophilic moieties cannot easily dissolve in or pass through the hydrophobic core of the membrane.
The difficulty level: Easy
The Concept Name: Membrane Permeability
Short cut solution: Hydrophobic membrane repels Hydrophilic (water-loving) substances.
Question 15
Question: Which of the following is not a feature of active transport of solutes in plants ?
Options:
A. Requires ATP
B. Occurs against concentration gradient
C. Non-selective
D. Occurs through membranes
Correct Answer: C
Year:
Solution: Active transport is uphill transport. This transport takes place against the electrochemical potential gradient and requires additional input of energy that chiefly comes from hydrolysis of ATP. It is highly selective.
Step Solution:
1. List the known features of Active Transport: Requires energy (ATP), "uphill" movement (against gradient), and involves specific carrier proteins.
2. Evaluate the term "highly selective": Transport proteins only allow specific molecules/ions to pass.
3. Identify the incorrect statement: Non-selective is incorrect because active transport is highly selective.
The difficulty level: Easy
The Concept Name: Features of Active Transport
Short cut solution: Carrier proteins = Specificity = Selectivity. (So "Non-selective" is wrong).
Question 17
Question: Active and passive transports across cell membrane differ in :
Options:
A. Passive transport is non-selective
B. Passive transport is along the concentration gradient while active transport is due to metabolic energy.
C. Active transport is more rapid
D. Passive transport is confined to anions while active transport in confined to cations.
Correct Answer: A
Year:
Solution: Active transport is selective for a particular ion... sodium/potassium channel... Passive transport is non-selective it occurs along the concentration gradient so this kind of channel allow to transport of many types of ions across the membrane.
Step Solution:
1. Recall the primary difference in selectivity: Active transport uses specific pumps.
2. Recall the primary difference in energy: Active uses ATP; Passive uses the natural gradient.
3. Identify the source's chosen distinction: It highlights that passive transport (like simple diffusion) lacks the specific "particularity" of active transport channels.
The difficulty level: Medium
The Concept Name: Selective Permeability/Transport
Short cut solution: Active = Specific (Selective); Passive = General (Non-selective).
Question 30
Question: Which of the following criteria does not pertain to facilitated transport?
Options:
A. Transport saturation
B. Uphill transport
C. Requirement of special membrane proteins
D. High selectivity
Correct Answer: B
Year:
Solution: Facilitated transport or facilitated division is the spontaneous passage of molecules or ions across a biological membrane passing through specific transmembrane integral proteins... importantly, neither channels nor carrier proteins require energy to facilitate the transport of molecules; they enable molecules to move down their concentration gradients (downhill transport).
Step Solution:
1. Identify the nature of Facilitated Transport: It is a form of diffusion.
2. Recall the rule of diffusion: Movement is always from high to low concentration (downhill).
3. Assess the options: Saturation, proteins, and selectivity are all features of protein-mediated transport.
4. Conclusion: Uphill transport is an active process and does not happen in facilitated diffusion.
The difficulty level: Easy
The Concept Name: Facilitated Diffusion
Short cut solution: Facilitated = Diffusion = Downhill only.
Question 42
Question: Passive absorption of minerals depends on
Options:
A. temperature
B. temperature and metabolic inhibitor
C. metabolic inhibitor
D. humidity
Correct Answer: A
Year:
Solution: Rate of salt absorption increases when temperature increases but to a certain limit... Rate of diffusion of ions and molecules increases at enhanced temperature due to their increased kinetic activity. Thus passive salt absorption will increase.
Step Solution:
1. Define passive absorption: It is driven by diffusion.
2. Identify the physics of diffusion: Movement depends on the kinetic energy of particles.
3. Relationship: Kinetic Energy $\propto$ Absolute Temperature ($T$).
4. Conclusion: Increased temperature enhances the rate of passive absorption.
The difficulty level: Medium
The Concept Name: Factors affecting Diffusion
Short cut solution: Temperature $\uparrow$ = Kinetic Activity $\uparrow$ = Passive Diffusion $\uparrow$.
Question 45
Question: The movement of ions against the concentration gradient will be
Options:
A. active transport
B. osmosis
C. diffusion
D. all of the above
Correct Answer: A
Year: 2000
Solution: Active transport involves movement of materials across the membrane against the concentration gradient of the solute particles. It requires energy in the form of ATP and carrier molecules.
Step Solution:
1. Identify the movement: "Against the concentration gradient."
2. Analyze "Diffusion" and "Osmosis": These are passive and move with the gradient.
3. Analyze "Active transport": It specifically pumps ions against a gradient using ATP.
The difficulty level: Easy
The Concept Name: Active Transport
Short cut solution: Against gradient = Active Transport.
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