Molecular Basis Of Inheritance

394 Questions Start Allen Test
Q101 Allen 3. RNA, TRANSCRIPTION MCQ
Main enzyme of transcription:—
A.
DNA dependent DNA polymerase
B.
DNA dependent RNA polymerase
C.
RNA dependent RNA polymerase
D.
RNA dependent DNA polymerase BN
Q102 Allen 3. RNA, TRANSCRIPTION MCQ
Removal of introns and joining of exons is called :-
A.
Capping
B.
Tailing
C.
Splicing
D.
AIl
Q103 Allen 4. GENETIC CODE, TRANSLATION MCQ
A codon in m-RNA has :-
A.
3-bases
B.
2-bases
C.
1-base
D.
Number of bases vary
Q104 Allen 4. GENETIC CODE, TRANSLATION MCQ
A DNA strand is directly involved in the synthesis of all the following except: -
A.
Another DNA
B.
t-RNA & m-RNA
C.
r-RNA
D.
Protein
Q105 Allen 4. GENETIC CODE, TRANSLATION MCQ
Genetic code was discovered by:-
A.
Nirenberg & Mathei
B.
Kornberg & Crick
C.
Khorana & Kornberg
D.
Gamow
Q106 Allen 4. GENETIC CODE, TRANSLATION MCQ
Genetic code was deciphered by enzymatically synthesizing the trinucleotides by:-
A.
Watson & Crick
B.
Beadle & Tatum
C.
Briggs & King
D.
M.W. Nirenberg
Q107 Allen 4. GENETIC CODE, TRANSLATION MCQ
Nirenberg synthesizedan m-RNA containing 34 poly-Adenine (A-A-A-A-A-A--) and found a polypeptide formed of 11 polylysine this proved that genetic code for lysine was :-
A.
one-adenine
B.
A-A doublet
C.
A-A-A triplet
D.
Many adenines
Q108 Allen 4. GENETIC CODE, TRANSLATION MCQ
64 Codons constitute genetic code because:-
A.
There was 64 types of amino acid
B.
64 types of t-RNA
C.
Genetic code is triplet
D.
There are 64 enzymes
Q109 Allen 4. GENETIC CODE, TRANSLATION MCQ
Which codon gives signal for the start of polypeptide (protein) chain synthesis:-
A.
AUG
B.
UGA
C.
GUA
D.
UAG
Q110 Allen 4. GENETIC CODE, TRANSLATION MCQ
The function of non-sense codons is:-
A.
To release polypeptide chain from m-RNA.
B.
To form an unspecified amino acid.
C.
To terminate the message of a genecontrolled protein synthesis.
D.
To convert a sense DNA into non-sense DNA.
Q111 Allen 4. GENETIC CODE, TRANSLATION MCQ
Termination of chain growth in protein synthesis is brought about by:-
A.
UUG, UGC, UCA
B.
UCG, GCG, ACC
C.
UAA, UAG, UGA
D.
UUG, UAG, UCG
Q112 Allen 4. GENETIC CODE, TRANSLATION MCQ
Genetic code determines: -
A.
Structural pattern of an organism
B.
Sequence of amino acids in protein chain
C.
Variation in offsprings
D.
Constancy of morphological trait
Q113 Allen 4. GENETIC CODE, TRANSLATION MCQ
m - RNA is attached with :-
A.
E.R.
B.
Ribosome
C.
Nucleus
D.
Lysosome
Q114 Allen 4. GENETIC CODE, TRANSLATION MCQ
Sometimes the starting codon is GUG in place of AUG, GUG normally code for:-
A.
Valine
B.
Glycine
C.
Methionine
D.
Tyrosine
Q115 Allen 4. GENETIC CODE, TRANSLATION MCQ
Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' codon ?
A.
UCG - Start
B.
UUU − Stop
C.
UGU – Leucine
D.
UAC – Tyrosine
Q116 Allen 4. GENETIC CODE, TRANSLATION MCQ
During translation initiation in prokaryotes, a GTP molecule is needed in :-
A.
Formation of formyl-met-tRNA
B.
Binding of 30S subunit of ribosome with mRNA
C.
Association of 30 S-mRNA with formylmet tRNA
D.
Association of 50 S subunit of ribosome with initiation complex
Q117 Allen 4. GENETIC CODE, TRANSLATION MCQ
Degeneration of a genetic code is attributed to the :-
A.
First member of a codon
B.
Second member of a codon
C.
Entire codon
D.
Third member of a codon
Q118 Allen 4. GENETIC CODE, TRANSLATION MCQ
What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA :-
A.
A polypeptide of 24 amino acids will be formed
B.
Two polypeptides of 24 and 25 amino acids will be formed
C.
A polypeptide of 49 amino acids will be formed
D.
A polypeptide of 25 amino acids will be formed
Q119 Allen 4. GENETIC CODE, TRANSLATION MCQ
A sequence of how many nucleotides in messenger RNA makes a codon for an amino acid?
A.
Three
B.
Four
C.
One
D.
Two
Q120 Allen 4. GENETIC CODE, TRANSLATION MCQ
A strand of DNA has following base sequence 3'-AAAAGTGACTAGTGA-5'. On transcription, it produces an m-RNA which of the following anticodon of t-RNA recognizes the third codon of this mRNA?
A.
AAA
B.
CUG
C.
GAC
D.
CTG
Q121 Allen 4. GENETIC CODE, TRANSLATION MCQ
Which one of the following statement is true for protein synthesis (translation)?
A.
Amino acids are directly recognized by mRNA
B.
The third base of the codon is less specific
C.
Only one codon codes for an amino acid
D.
Every t-RNA molecule has more than one amino acid attachment site
Q122 Allen 4. GENETIC CODE, TRANSLATION MCQ
Translation is the process in which: -
A.
DNA is formed on DNA template
B.
RNA is formed on DNA template
C.
DNA is formed on RNA template
D.
Protein is formed from RNA message
Q123 Allen 4. GENETIC CODE, TRANSLATION MCQ
In a polypeptide chain of 125 amino acids, if the 25th codon is mutated to UAA, then :-
A.
A polypeptide of 124 amino acid is formed
B.
A polypeptide of 25 amino acid is formed
C.
A polypeptide of 24 amino acid is formed
D.
Any of the above can be possible
Q124 Allen 4. GENETIC CODE, TRANSLATION MCQ
The first codon discovered by Nirenberg and Matthaei was :-
A.
CCC
B.
GGG
C.
UUU
D.
AAA
Q125 Allen 4. GENETIC CODE, TRANSLATION MCQ
t-RNA attaches, amino acid at its :-
A.
3' end
B.
5' end
C.
Anticodon
D.
Loop