Question 1: Palette 1/394

Allen 2006 MCQ

The sequence of which chromosome was completed in May 2006?

A

Chromosome number 1

B

Chromosome number 2

C

Chromosome number 5

D

Chromosome number 10 BMI343

Question 2: Palette 2/394

Allen 2000 MCQ

E.coli has only 4.6 × 10⁶ base pairs and completes the process of replication within 18 minutes; then the average rate of polymerisation is approximately: -

A

2000 base pairs/second

B

3000 base pairs/second

C

4000 base pairs/second

D

1000 base pairs/second

Question 3: Palette 3/394

Allen 2000 MCQ

What is the rate of polymerisation in E. coli?

A

20,000 bp per second

B

2000 nucleotides per second

C

2000 bp per minute

D

2000 bp per second

Question 4: Palette 4/394

Allen 2000 MCQ

Due to high degree of polymorphism, size of VNTR varies from :-

A

0.1 − 2 kb

B

0.1 − 2000 kb

C

0.1 − 20 kb

D

0.1 − 200 kb

Question 5: Palette 5/394

Allen 1961 MCQ

A functional complex comprising a cluster of genes including structural gene, a promoter gene, an operator gene and a regulator gene was discovered by :-

A

Beadle and Tatum (1958)

B

Watson and Crick (1953)

C

Jacob and Monod (1961)

D

Britten and Davidson

Question 6: Palette 6/394

Allen 1958 MCQ

The unequivocal proof that DNA is the genetic material came from the experiments of :

A

Hershey and Chase (1952)

B

Frederik Griffith (1928)

C

Watson and Crick

D

Meselson and Stal

Question 7: Palette 7/394

Allen MCQ

In eukaryotic cell circular and double stranded DNA occurs in :-

A

Golgi body

B

Mitochondria

C

Nucleus

D

Ribosome

Question 8: Palette 8/394

Allen MCQ

Double helix model of DNA which was proposed by Watson and Crick was of:-

A

C-DNA

B

B-DNA

C

D-DNA

D

Z-DNA

Question 9: Palette 9/394

Allen MCQ

If there are 10,000 nitrogenous base pairs in a DNA then how many nucleotides are there:-

A

500

B

10,000

C

20,000

D

40,000

Question 10: Palette 10/394

Allen MCQ

Double helix model of DNA was proposed by :

A

Watson and Crick

B

Schleiden Schwann

C

Singer and Nicholson

D

Kornberg and Khurana

Question 11: Palette 11/394

Allen MCQ

Back bone in structure of DNA molecule is made up of :-

A

Pentose Sugar and phosphate

B

Hexose sugar and phosphate

C

Purine and pyrimidine

D

Sugar and phosphate

Question 12: Palette 12/394

Allen MCQ

Substance common in DNA and RNA :-

A

Hexose Sugar

B

Histamine

C

Thymine

D

Phosphate groups

Question 13: Palette 13/394

Allen MCQ

Nucleotide is :-

A

N₂ - base, pentose sugar and phosphoric acid

B

Nitrogen, Hexose sugar and phosphoric acid

C

Nitrogen base and pentose sugar

D

Nitrogen base, trioses and phosphoric acid BMI007

Question 14: Palette 14/394

Allen MCQ

Unit of nucleic acids are:-

A

Phosphoric acid

B

Nitrogenous bases

C

Pentose Sugar

D

Nucleotides

Question 15: Palette 15/394

Allen MCQ

Which element is not found in nitrogenous base?

A

Nitrogen

B

Hydrogen

C

Carbon

D

Phosphorus

Question 16: Palette 16/394

Allen MCQ

DNA was first discovered by:-

A

Miescher

B

Robert Brown

C

Flemming

D

Watson & Crick BMI010

Question 17: Palette 17/394

Allen MCQ

Nucleic acid (DNA) is not found in:-

A

Nucleus & nucleolus

B

Peroxisome & ribosome

C

Mitochondria & plastid

D

Chloroplast & nucleosome

Question 18: Palette 18/394

Allen MCQ

DNA is not present in :-

A

Mitochondria

B

Chloroplast

C

Bacteriophage

D

TMV

Question 19: Palette 19/394

Allen MCQ

A nucleic acid contains thymine or methylated uracil then it should be :-

A

DNA

B

RNA

C

Either DNA or RNA

D

RNA of bacteria

Question 20: Palette 20/394

Allen MCQ

Prokaryotic genetic system contains :-

A

DNA & histones

B

RNA & histones

C

Either DNA or histones

D

DNA but no histones

Question 21: Palette 21/394

Allen MCQ

A N₂- base together with pentose sugar and phosphate forms (or) building - block unit of nucleic acid is :-

A

Nucleoside

B

Polypeptide

C

Nucleotide

D

Amino acid

Question 22: Palette 22/394

Allen MCQ

Which of the following is not a pyrimidine N₂ base?

A

Thymine

B

Cytosine

C

Guanine

D

Uracil

Question 23: Palette 23/394

Allen MCQ

The purine & pyrimidine pairs of complementary strands of DNA are held together by :-

A

H - bonds

B

O - bonds

C

C - bonds

D

N - bonds

Question 24: Palette 24/394

Allen MCQ

Number of H - bonds between guanine and cytosine are :-

A

One

B

Two

C

Three

D

Four

Question 25: Palette 25/394

Allen MCQ

Which purine & pyrimidine bases are paired together by H - bonds in DNA ?

A

AC & GT

B

GC & AT

C

GA & TC

D

None of the above

Question 26: Palette 26/394

Allen MCQ

A single stranded DNA is present in:-

A

TMV

B

Salmonella

C

φx174

D

Bacteria

Question 27: Palette 27/394

Allen MCQ

What is the nature of the 2 strands of a DNA duplex ?

A

Identical & Complimentary

B

Antiparallel & complimentary

C

Dissimilar & non complimentary

D

Antiparallel & non complimentary

Question 28: Palette 28/394

Allen MCQ

On an average, how many purine N₂ bases are present in single coil of DNA :-

A

Four

B

Five

C

Ten

D

Uncertain BMI022

Question 29: Palette 29/394

Allen MCQ

Distance between two nucleotide pairs of DNA is :-

A

0.34 nm

B

34 Å

C

3.4 μ

D

34 nm RMI023

Question 30: Palette 30/394

Allen MCQ

In a double strand DNA amount of Guanine is 35% then what will be the amount of cytosine:

A

70%

B

15%

C

30%

D

35%

Question 31: Palette 31/394

Allen MCQ

Chargaff 's rule is given as :-

A

Purines ≠ Pyrimidines

B

A + G = T+ C

C

A+ U = G + C

D

A + T / G + C = Const.

Question 32: Palette 32/394

Allen MCQ

In RNA, Nucleotides are bonded by :-

A

H - bonds

B

Phosphodiester bonds

C

lonic bonds

D

Salt linkage

Question 33: Palette 33/394

Allen MCQ

A nucleoside differs from a nucleotide is not having :-

A

Phosphate

B

Sugar

C

Phosphate & sugar

D

Nitrogen base

Question 34: Palette 34/394

Allen MCQ

Wilkins X-ray diffraction showed the diameter of the DNA helix is :-

A

10 Å

B

20 Å

C

30 Å

D

40 Å

Question 35: Palette 35/394

Allen MCQ

In the DNA of an animal percentage of Adenine is 30 then percentage of Guanine will be :-

A

40

B

30

C

20

D

70

Question 36: Palette 36/394

Allen MCQ

Length of one loop of B- DNA:-

A

3.4 nm.

B

0.34 nm.

C

20 nm.

D

10 nm.

Question 37: Palette 37/394

Allen MCQ

If base order in one chain of DNA is "ATCGA" then how many no. of H-bond found in DNA duplex :-

A

20

B

12

C

10

D

11

Question 38: Palette 38/394

Allen MCQ

In DNA purine nitrogen bases are :

A

Uracil and Guanine

B

Guanine and Adenine

C

Adenine and cytosine

D

None

Question 39: Palette 39/394

Allen MCQ

Two free ribonucleotide units are interlinked with :-

A

Peptide bond

B

Disulphide bond

C

Hydrogen bond

D

Phosphodiester bond

Question 40: Palette 40/394

Allen MCQ

Short DNA segment has 80 thymine and 90 guanine bases. The total number of nucleotides are :-

A

160

B

40

C

80

D

340

Question 41: Palette 41/394

Allen MCQ

Prokaryotic DNA is :-

A

double stranded circular

B

single stranded circular

C

double stranded linear

D

double stranded RNA as nucleic acid

Question 42: Palette 42/394

Allen MCQ

Nucleoside is :

A

Polymer of nucleic acid

B

Phosphoric acid + base

C

Phosphoric acid + sugar + base

D

Sugar + base

Question 43: Palette 43/394

Allen MCQ

The back bone of RNA is consists of which of the following sugar?

A

Deoxyribose

B

Ribose

C

Sucrose

D

Maltose

Question 44: Palette 44/394

Allen MCQ

In a nucleotide H₃PO₄ binds to which carbon atom of pentose sugar?

A

Only 1st carbon

B

Only 3rd carbon

C

Only 5th carbon

D

Both 3rd and 5th carbon

Question 45: Palette 45/394

Allen MCQ

DNA is acidic due to:-

A

Sugar

B

Phosphoric acid

C

Purine

D

Pyrimidine

Question 46: Palette 46/394

Allen MCQ

RNA contains which of the following base, in place of Thymine of DNA?

A

Thymine

B

Uracil

C

Adenine

D

None of these

Question 47: Palette 47/394

Allen MCQ

Genetic information are transferred from nucleus to cytoplasm of cell through :-

A

DNA

B

RNA

C

Lysosomes

D

ACTH

Question 48: Palette 48/394

Allen MCQ

If one strand of double stranded DNA, consists of the sequence 3'-ATTCGTAC–5', then the complementary sequence must be:-

A

5'-UAAGCAUG-3'

B

3'-TAAGCATG–5'

C

5'-TAAGCATG-3'

D

5'-TAAGCATG–3' in the reverse direction

Question 49: Palette 49/394

Allen MCQ

DNA molecule has uniform diameter due to:

A

Double stranded

B

Presence of phosphate

C

Specific base pairing between purine and pyrimidine

D

Specific base pairing between purine and purine

Question 50: Palette 50/394

Allen MCQ

Following structure is related to which compound?

A

Adenine

B

Guanine

C

Uracil

D

Thymine

Question 51: Palette 51/394

Allen MCQ

If the sequence of bases in one strand of DNA is known then the sequence in other strand can be predicted on the basis of: –

A

Antiparallel

B

Complementary

C

Polarity

D

Coiling

Question 52: Palette 52/394

Allen MCQ

In process of replication deoxyribonucleoside triphosphate:-

A

acting as substrate

B

providing energy for polymerisation reaction

C

acting as an enzyme

D

Both (1) and (2)

Question 53: Palette 53/394

Allen MCQ

DNA Replication occurs at :-

A

G₀ & G1

B

G₂-stage

C

S-Stage

D

Mitotic phase

Question 54: Palette 54/394

Allen MCQ

A DNA molecule in which both strands have radioactive thymidine is allowed to duplicate in an environment containing non-radioactive thymidine. What will be the exact number of DNA molecules that contains the radioactive thymidine after 3 duplications?

A

One

B

Two

C

Four

D

Eight BMI049

Question 55: Palette 55/394

Allen MCQ

A bacterium with completely radioactive DNA was allowed to replicate in a nonradioactive medium for two generation what % of the bacteria should contain radioactive DNA ?

A

100 %

B

50 %

C

25 %

D

12.5 %

Question 56: Palette 56/394

Allen MCQ

In the base sequence of one strand of DNA is GAT, TAG, CAT, GAC what shall be the sequence of its complementary strand?

A

CAT, CTG, ATC, GTA

B

GTA, ATC, CTG, GTA

C

ATC, GTA, CTG, GTA

D

CTA, ATC, GTA, CTG

Question 57: Palette 57/394

Allen MCQ

Method of DNA replication in which two strands of DNA separates and synthesize new strands?

A

Dispersive

B

Conservative

C

Semiconservative

D

Non-conservative

Question 58: Palette 58/394

Allen MCQ

During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and :-

A

RNA primers are not involved

B

is facilitated by telomerase

C

moves in one direction of the site

D

moves in bi-directional way

Question 59: Palette 59/394

Allen MCQ

The nature of DNA replication is :-

A

Conservation

B

Non-conservative

C

Semi-conservative

D

Cyanobacteria

Question 60: Palette 60/394

Allen MCQ

The direction of DNA replication is :-

A

From 5' end towards 3' end

B

From 3' end towards 5' end

C

Amino terminus to carboxy terminus

D

Carboxy terminus to amino terminus BMI055

Question 61: Palette 61/394

Allen MCQ

Semiconservative replication of DNA was proposed by :-

A

Watson and Crick

B

Bateson and Punnett

C

Meselson and Stahl

D

Avery, McCarty and MacLeod

Question 62: Palette 62/394

Allen MCQ

Which of the following enzyme is used in DNA multiplication?

A

RNA polymerase

B

DNA endonuclease

C

Exonuclease

D

DNA Polymerase

Question 63: Palette 63/394

Allen MCQ

Mode of DNA replication in E. coli is :-

A

Conservative and unidirectional

B

Semi conservative and unidirectional

C

conservative and bidirectional

D

Semi conservative and bidirectional

Question 64: Palette 64/394

Allen MCQ

Which of the following enzyme is used to join DNA fragments?

A

Terminase

B

Endonuclease

C

Ligase

D

DNA polymerase

Question 65: Palette 65/394

Allen MCQ

Okazaki fragments are synthesised on :-

A

Leading strands of DNA only

B

Lagging strands of DNA only

C

Both leading and lagging strands of DNA

D

Complementary DNA

Question 66: Palette 66/394

Allen MCQ

DNA replication includes :-

A

DNA ligase

B

DNA polymerase and ligase

C

RNA polymerase and ligase

D

All of these

Question 67: Palette 67/394

Allen MCQ

In DNA replication, the primer is :-

A

A small deoxyribonucleotide polymer

B

A small ribonucleotide polymer

C

Helix destabilizing protein

D

Enzyme taking part in joining nucleotides of new strand

Question 68: Palette 68/394

Allen MCQ

The strand of DNA, which does not code for anything is referred to as :-

A

Template strand

B

Antisense strand

C

Coding strand

D

Noncoding strand

Question 69: Palette 69/394

Allen MCQ

During DNA replication discontinuously synthesized fragments are later joined by the enzyme :—

A

Ligase

B

DNA polymerase

C

RNA primer

D

Primase

Question 70: Palette 70/394

Allen MCQ

Replication fork is :—

A

Large opening of the DNA helix

B

Small opening of the DNA helix

C

Tightly coiled part of DNA helix

D

Loosely coiled part of DNA helix

Question 71: Palette 71/394

Allen MCQ

The DNA dependent DNA polymerase catalyse polymerisation in:—

A

3' → 5' direction

B

5' → 3' direction

C

Depend on the nature of template strand

D

Both (1) and (2) BMI066

Question 72: Palette 72/394

Allen MCQ

Main enzyme of DNA replication is :—

A

DNA dependent RNA polymerase

B

DNA dependent DNA polymerase

C

RNA dependent RNA polymerase

D

RNA dependent DNA polymerase BN

Question 73: Palette 73/394

Allen MCQ

The Process of copying genetic information from one strand of DNA intoY is termed as Z

A

Transcription - RNA

B

RNA - Transcription

C

DNA - Translation

D

Replication - RNA

Question 74: Palette 74/394

Allen MCQ

Code in RNA corresponding to AGCT in DNA:

A

TACA

B

UCGA

C

TCGA

D

AGUC

Question 75: Palette 75/394

Allen MCQ

Which of the following is called adaptor molecule?

A

DNA

B

m-RNA

C

t-RNA

D

RNA

Question 76: Palette 76/394

Allen MCQ

Which may be attached with Adenine base in RNA ?

A

Guanine

B

Cytosine

C

Uracil

D

Thymine

Question 77: Palette 77/394

Allen MCQ

In the base sequence of one strand of DNA is CAT, TAG , CAT, CAT, GAC what would be the base sequence of its complementary m-RNA?

A

GUA, GUA, CUG, AUC, CUG

B

AUG, CUG, CUC, GUA, CUG

C

GUA, AUC, GUA, CUG

D

GUC, CUG, CUG, CUA, CUU

Question 78: Palette 78/394

Allen MCQ

The process by which DNA of the nucleus passes genetic information to m-RNA is called?

A

Transcription

B

Translocation

C

Translation

D

Transportation

Question 79: Palette 79/394

Allen MCQ

A sequence of three consecutive bases in a t-RNA molecule which specifically binds to a complementary codon sequence in m RNA is known as?

A

Triplet

B

Non - sense codon

C

Anti codon

D

Termination codon

Question 80: Palette 80/394

Allen MCQ

t-RNA attach to larger subunit of ribosomes with the help of which loop :-

A

DHU − loop

B

T ψ C loop

C

Anticodon loop

D

Minor loop

Question 81: Palette 81/394

Allen MCQ

In three dimensional view the molecule of t-RNA is:-

A

L-shaped

B

S-shaped

C

Y- shaped

D

E-shaped

Question 82: Palette 82/394

Allen MCQ

During transcription, the DNA site at which RNA polymerase binds is called?

A

Promoter

B

Regulator

C

Receptor

D

Enhancer

Question 83: Palette 83/394

Allen MCQ

During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the mRNA would be:-

A

TATGC

B

TCTGG

C

UAUGC

D

UATGC

Question 84: Palette 84/394

Allen MCQ

Which form of RNA has a structure resembling clover leaf ?

A

rRNA

B

hnRNA

C

mRNA

D

tRNA

Question 85: Palette 85/394

Allen MCQ

Which one of the following makes use of RNA as a template to synthesize DNA?

A

DNA dependant RNA polymerase

B

DNA polymerase

C

Reverse transcriptase

D

RNA polymerase

Question 86: Palette 86/394

Allen MCQ

The enzyme responsible for transcription is

A

DNA polymerase-I

B

RNA polymerase

C

Reverse transcriptase

D

DNA polymerase-III

Question 87: Palette 87/394

Allen MCQ

If the base sequence in DNA is 5' AAAA 3' then the bases sequence in m-RNA is :-

A

5' UUUU 3'

B

3' UUUU 5'

C

5' AAAA 3'

D

3' TTTT 5'

Question 88: Palette 88/394

Allen MCQ

Correct order of molecular weight is :-

A

DNA < r-RNA < t-RNA

B

DNA < m-RNA < r-RNA

C

t-RNA < m-RNA < DNA

D

t-RNA < DNA < m-RNA

Question 89: Palette 89/394

Allen MCQ

The genes are responsible for growth and differentiation in an organism through regulation of :-

A

Translocation

B

Transformation

C

Transduction and translation

D

Translation and transcription BMI084

Question 90: Palette 90/394

Allen MCQ

Method by which information reaches from DNA to RNA is ?

A

Transcription

B

Translation

C

Transformation

D

Transduction

Question 91: Palette 91/394

Allen MCQ

DNA acts as a template for synthesis of :-

A

RNA

B

DNA

C

Both (1) and (2)

D

Protein

Question 92: Palette 92/394

Allen MCQ

Which is soluble RNA :-

A

hnRNA

B

rRNA

C

mRNA

D

tRNA

Question 93: Palette 93/394

Allen MCQ

Portion of gene which is transcribed but not translated is ?

A

exon

B

intron

C

cistron

D

codon

Question 94: Palette 94/394

Allen MCQ

The smallest RNA is :-

A

r-RNA

B

m-RNA

C

t-RNA

D

nuclear RNA

Question 95: Palette 95/394

Allen MCQ

The most abundant RNA of cell is :-

A

r-RNA

B

t-RNA

C

m-RNA

D

None of these

Question 96: Palette 96/394

Allen MCQ

One strand of DNA (non template) has base sequence CAG, TCG, GAT. What will be the sequence of bases in m-RNA?

A

AGC, CTA, CTA

B

GTC, AGC, CTC

C

CAG. UCG. GAU

D

GAC. TAG. CTA

Question 97: Palette 97/394

Allen MCQ

Reverse transcription was discovered by :-

A

Watson and Crick

B

Khorana

C

Temin an Baltimore

D

Miescher

Question 98: Palette 98/394

Allen MCQ

Mature eukaryotic m-RNA is recognised by:-

A

Shine Dalgarno sequence at 5'end

B

7-methyl guanosine at 5' end and polyadenine bases at 3'end

C

Anti shine Dalgarno sequence at 5'end

D

Presence of coding and noncoding sequence

Question 99: Palette 99/394

Allen MCQ

Transcription unit in DNA is composed of :-

A

Promoter

B

Structural gene

C

Terminator

D

AIl

Question 100: Palette 100/394

Allen MCQ

In DNA promoter is the site for the initiation of :-

A

Replication

B

Translation

C

Transcription

D

Both (2) and (3)

Question 101: Palette 101/394

Allen MCQ

Main enzyme of transcription:—

A

DNA dependent DNA polymerase

B

DNA dependent RNA polymerase

C

RNA dependent RNA polymerase

D

RNA dependent DNA polymerase BN

Question 102: Palette 102/394

Allen MCQ

Removal of introns and joining of exons is called :-

A

Capping

B

Tailing

C

Splicing

D

AIl

Question 103: Palette 103/394

Allen MCQ

A codon in m-RNA has :-

A

3-bases

B

2-bases

C

1-base

D

Number of bases vary

Question 104: Palette 104/394

Allen MCQ

A DNA strand is directly involved in the synthesis of all the following except: -

A

Another DNA

B

t-RNA & m-RNA

C

r-RNA

D

Protein

Question 105: Palette 105/394

Allen MCQ

Genetic code was discovered by:-

A

Nirenberg & Mathei

B

Kornberg & Crick

C

Khorana & Kornberg

D

Gamow

Question 106: Palette 106/394

Allen MCQ

Genetic code was deciphered by enzymatically synthesizing the trinucleotides by:-

A

Watson & Crick

B

Beadle & Tatum

C

Briggs & King

D

M.W. Nirenberg

Question 107: Palette 107/394

Allen MCQ

Nirenberg synthesizedan m-RNA containing 34 poly-Adenine (A-A-A-A-A-A--) and found a polypeptide formed of 11 polylysine this proved that genetic code for lysine was :-

A

one-adenine

B

A-A doublet

C

A-A-A triplet

D

Many adenines

Question 108: Palette 108/394

Allen MCQ

64 Codons constitute genetic code because:-

A

There was 64 types of amino acid

B

64 types of t-RNA

C

Genetic code is triplet

D

There are 64 enzymes

Question 109: Palette 109/394

Allen MCQ

Which codon gives signal for the start of polypeptide (protein) chain synthesis:-

A

AUG

B

UGA

C

GUA

D

UAG

Question 110: Palette 110/394

Allen MCQ

The function of non-sense codons is:-

A

To release polypeptide chain from m-RNA.

B

To form an unspecified amino acid.

C

To terminate the message of a genecontrolled protein synthesis.

D

To convert a sense DNA into non-sense DNA.

Question 111: Palette 111/394

Allen MCQ

Termination of chain growth in protein synthesis is brought about by:-

A

UUG, UGC, UCA

B

UCG, GCG, ACC

C

UAA, UAG, UGA

D

UUG, UAG, UCG

Question 112: Palette 112/394

Allen MCQ

Genetic code determines: -

A

Structural pattern of an organism

B

Sequence of amino acids in protein chain

C

Variation in offsprings

D

Constancy of morphological trait

Question 113: Palette 113/394

Allen MCQ

m - RNA is attached with :-

A

E.R.

B

Ribosome

C

Nucleus

D

Lysosome

Question 114: Palette 114/394

Allen MCQ

Sometimes the starting codon is GUG in place of AUG, GUG normally code for:-

A

Valine

B

Glycine

C

Methionine

D

Tyrosine

Question 115: Palette 115/394

Allen MCQ

Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' codon ?

A

UCG - Start

B

UUU − Stop

C

UGU – Leucine

D

UAC – Tyrosine

Question 116: Palette 116/394

Allen MCQ

During translation initiation in prokaryotes, a GTP molecule is needed in :-

A

Formation of formyl-met-tRNA

B

Binding of 30S subunit of ribosome with mRNA

C

Association of 30 S-mRNA with formylmet tRNA

D

Association of 50 S subunit of ribosome with initiation complex

Question 117: Palette 117/394

Allen MCQ

Degeneration of a genetic code is attributed to the :-

A

First member of a codon

B

Second member of a codon

C

Entire codon

D

Third member of a codon

Question 118: Palette 118/394

Allen MCQ

What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA :-

A

A polypeptide of 24 amino acids will be formed

B

Two polypeptides of 24 and 25 amino acids will be formed

C

A polypeptide of 49 amino acids will be formed

D

A polypeptide of 25 amino acids will be formed

Question 119: Palette 119/394

Allen MCQ

A sequence of how many nucleotides in messenger RNA makes a codon for an amino acid?

A

Three

B

Four

C

One

D

Two

Question 120: Palette 120/394

Allen MCQ

A strand of DNA has following base sequence 3'-AAAAGTGACTAGTGA-5'. On transcription, it produces an m-RNA which of the following anticodon of t-RNA recognizes the third codon of this mRNA?

A

AAA

B

CUG

C

GAC

D

CTG

Question 121: Palette 121/394

Allen MCQ

Which one of the following statement is true for protein synthesis (translation)?

A

Amino acids are directly recognized by mRNA

B

The third base of the codon is less specific

C

Only one codon codes for an amino acid

D

Every t-RNA molecule has more than one amino acid attachment site

Question 122: Palette 122/394

Allen MCQ

Translation is the process in which: -

A

DNA is formed on DNA template

B

RNA is formed on DNA template

C

DNA is formed on RNA template

D

Protein is formed from RNA message

Question 123: Palette 123/394

Allen MCQ

In a polypeptide chain of 125 amino acids, if the 25th codon is mutated to UAA, then :-

A

A polypeptide of 124 amino acid is formed

B

A polypeptide of 25 amino acid is formed

C

A polypeptide of 24 amino acid is formed

D

Any of the above can be possible

Question 124: Palette 124/394

Allen MCQ

The first codon discovered by Nirenberg and Matthaei was :-

A

CCC

B

GGG

C

UUU

D

AAA

Question 125: Palette 125/394

Allen MCQ

t-RNA attaches, amino acid at its :-

A

3' end

B

5' end

C

Anticodon

D

Loop

Question 126: Palette 126/394

Allen MCQ

Out of 64 codons only 61 codes for the 20 different amino acids. This character of genetic code is called :-

A

Degeneracy

B

Non ambiguous nature

C

Universal

D

Overlapping

Question 127: Palette 127/394

Allen MCQ

Anticodons are found in :-

A

mRNA

B

tRNA

C

rRNA

D

In all

Question 128: Palette 128/394

Allen MCQ

One-gene-one enzyme hypothesis was proposed by:-

A

Beadle and Tatum

B

Jacob and Monod

C

Lederberg

D

Watson and Crick

Question 129: Palette 129/394

Allen MCQ

Which of the following RNA play structural and catalytic role during translation?

A

m-RNA

B

t-RNA

C

r-RNA

D

AIl

Question 130: Palette 130/394

Allen MCQ

Transfer of genetic information from a polymer of nucleotides to a polymer of amino acid is :—

A

Replication

B

Transcription

C

Translation

D

Reverse transcription

Question 131: Palette 131/394

Allen MCQ

Translation refers to the process of :—

A

Polymerisation of nitrogen bases

B

Polymerisation of nucleotides

C

Polymerisation of nucleosides

D

Polymerisation of amino acids

Question 132: Palette 132/394

Allen MCQ

Gene and cistron words are sometimes used synonymously because:-

A

One cistron contains many genes

B

One gene contains many cistrons

C

One gene contains one cistron

D

One gene contains no cistron

Question 133: Palette 133/394

Allen MCQ

A gene containing multiple exons and at least one intron is termed as :-

A

split gene

B

operator gene

C

synthetic gene

D

epistatic gene

Question 134: Palette 134/394

Allen MCQ

Gene which is responsible for the synthesis of a polypeptide chain is called :-

A

Promotor gene

B

Structural gene

C

Regulator gene

D

Operator gene

Question 135: Palette 135/394

Allen MCQ

What does "lac" refer to, in what we call the lac operon ?

A

Lactose

B

Lactase

C

Lac insect

D

The number 1,00,000

Question 136: Palette 136/394

Allen MCQ

Which of the following is not produced by E. coli in the lactose operon ?

A

βgalactosidase

B

Transacetylase

C

Lactose dehydrogenase

D

Lactose permease

Question 137: Palette 137/394

Allen MCQ

Who explained the operon model for the first time?

A

Francois Jacob

B

Jacques Monod

C

Francois Jacob and Jacques Monod

D

Beadle & Tatum

Question 138: Palette 138/394

Allen MCQ

The accessibility of promotor regions of prokaryotic DNA by RNA polymerase is in many cases regulated by the interaction of some protein with sequences termed as :—

A

Promoter

B

Operator

C

Regulator

D

Cistron

Question 139: Palette 139/394

Allen MCQ

Regulation of lac operon by repressor is referred to as :—

A

Positive regulation

B

Negative regulation

C

Both (1) and (2)

D

None

Question 140: Palette 140/394

Allen MCQ

Which is incorrect?

A

i-gene codes for the repressor of lac operon

B

z-gene codes for the beta-galactosidase

C

y-gene codes for transacetylase

D

three gene products are required for metabolism of lactose

Question 141: Palette 141/394

Allen MCQ

Which is the primary step for regulation of gene expression, in eukaryotes?

A

Transport of m-RNA from nucleus to the cytoplasm

B

Translational level

C

Processing level

D

Transcriptional level

Question 142: Palette 142/394

Allen MCQ

Find out the correct sequence of structural gene in lac operon :-

A

y, a, z

B

a, z, y

C

z, y, a

D

z, a y

Question 143: Palette 143/394

Allen MCQ

The concept of sudden genetic change which breeds true in an organism is visualized as ?

A

Natural selection

B

Inheritance of acquired characters

C

Mutation

D

Independent assortment

Question 144: Palette 144/394

Allen MCQ

Mutation is :-

A

An abrupt or discontinuous change which is inherited

B

A factor for plant growth

C

A change which affects parents only and is never inherited

D

A change which affects the offspring of F₂ generation

Question 145: Palette 145/394

Allen MCQ

The exchange of chromosomal parts between non homologous pairs of chromosome :-

A

Crossing over/Transduction

B

Translocation

C

Inversion

D

Transition

Question 146: Palette 146/394

Allen MCQ

Which of the following can be called a mutation?

A

The halving of the chromosome number at meiosis

B

The doubling of the chromosome after syngamy

C

The possession of an additional chromosome

D

All the above

Question 147: Palette 147/394

Allen MCQ

Mutations are generally :-

A

Dominant

B

Recessive

C

Codominant

D

Incompletely dominant

Question 148: Palette 148/394

Allen MCQ

Genetic or gene mutations occur in :-

A

DNA

B

RNA

C

Protein

D

RNA & protein both

Question 149: Palette 149/394

Allen MCQ

Which of the following undergoes change in mutation?

A

Chromosome

B

Structure of gene

C

Sequence of gene

D

Any of the above

Question 150: Palette 150/394

Allen MCQ

The locus of point mutation is generally :-

A

Gene

B

Chromosome

C

Centromere

D

Nucleus

Question 151: Palette 151/394

Allen MCQ

In the octaploid wheat (56), the haploid (n) and basic numbers (x) of chromosomes are:

A

n = 21, x = 7

B

n = 28, x = 7

C

n = 7 x = 28

D

n = 7, x = 21

Question 152: Palette 152/394

Allen MCQ

The smallest unit of genetic material which upon mutation produce a phenotypic effect is:

A

Mutons

B

Recon

C

Gene

D

Cistron

Question 153: Palette 153/394

Allen MCQ

Ultimate source of genetic variation is (OR) the process which provides raw material for evolution is:-

A

Sexual reproduction

B

Meiosis

C

Mutation

D

Independent assortment

Question 154: Palette 154/394

Allen MCQ

Type of gene mutation which involves replacement of purine with pyrimidine or vice versa (OR) The substitution of one type of base with another type of base is :-

A

Transduction

B

Transversion

C

Translocation

D

Transcription

Question 155: Palette 155/394

Allen MCQ

The minimum requirement for mutation is:-

A

Change of triplet codon

B

Change in single nucleotide

C

Change in whole DNA

D

Change in single strand of DNA

Question 156: Palette 156/394

Allen MCQ

Mutations are :-

A

Always useful

B

Mostly useful

C

Never useful

D

Rarely useful BMI152

Question 157: Palette 157/394

Allen MCQ

Sickle cell anaemia is an example of :-

A

Frame shift mutation

B

Point mutation

C

Segmental mutation

D

Gibberish mutation BMI153

Question 158: Palette 158/394

Allen MCQ

The most striking example of frame shift mutation was found in a disease called :-

A

Sickle cell anaemia

B

Colour blindness

C

Lesch-Nyhan Syndrome

D

Thalassemia

Question 159: Palette 159/394

Allen MCQ

A nutritionally wild type organism, which does not require any additional growth supplement is known as :-

A

Holotype

B

Auxotroph

C

Prototroph

D

Phenotype

Question 160: Palette 160/394

Allen MCQ

Given below is the representation of a kind of chromosomal mutation : What is the kind of mutation represented? A B C D E F G H A E F G H D C B

A

deletion

B

duplication

C

inversion

D

reciprocal translocation

Question 161: Palette 161/394

Allen MCQ

The "cri-du-chat" syndrome is caused by change in chromosome structure involving:-

A

Deletion

B

Duplication

C

Inversion

D

Translocation

Question 162: Palette 162/394

Allen MCQ

A class of mutation induced by addition or deletion of a nucleotide is called :-

A

Missense

B

Non-sense

C

Substitution

D

frame shift

Question 163: Palette 163/394

Allen MCQ

Chromosomes with genes abcdefg becoming abedcfg is :-

A

duplication

B

deletion

C

translocation

D

inversion

Question 164: Palette 164/394

Allen MCQ

Gene mutation is :-

A

change in the number of chromosome

B

mutation in the phosphodiester linkage

C

mutation in the chromosomes

D

change in the sequence of nitrogenous bases

Question 165: Palette 165/394

Allen MCQ

Chromosome number 2n-1 is an example of:-

A

trisomy

B

euploidy

C

polyploidy

D

monosomy

Question 166: Palette 166/394

Allen MCQ

After a mutation at a genetic locus the character of an organism changes due to the change in :-

A

protein structure

B

DNA replication

C

protein synthesis pattern

D

RNA transcription pattern.

Question 167: Palette 167/394

Allen MCQ

DNA finger printing was invented by :—

A

Kary Mullis

B

Alec Jeffery

C

Dr. Paul Berg

D

Francis Collins

Question 168: Palette 168/394

Allen MCQ

Which one of the following pairs of terms/ names mean one and the same thing

A

Gene pool — genome

B

Codon — gene

C

Cistron — triplet

D

DNA Fingerprinting — DNA profiling

Question 169: Palette 169/394

Allen MCQ

Which step does not involve in DNA finger printing-

A

Southern blotting

B

Gel electrophoresis

C

Restriction enzyme digestion

D

Northern blotting

Question 170: Palette 170/394

Allen MCQ

The technique of transferring DNA fragment separated on agarose gel to a synthetic membrane such as nitrocellulose is known as-

A

Northern blotting

B

Southern blotting

C

Western blotting

D

Dot blotting DMI1CC

Question 171: Palette 171/394

Allen MCQ

Western blotting is used for the identification of :-

A

DNA

B

RNA

C

Protein

D

All the above

Question 172: Palette 172/394

Allen MCQ

The approximate number of genes contained in the genome of Kalpana Chawla was :-

A

40,000

B

30,000

C

80,000

D

1,00,000

Question 173: Palette 173/394

Allen MCQ

The transfer of protein from electrophoretic gel to nitrocellulose membrane is known as

A

transferase

B

northern blotting

C

western blotting

D

southern blotting

Question 174: Palette 174/394

Allen MCQ

Which of the following is not associated with HGP ?

A

Bioinformatics

B

cloing C & YAC

C

Automated DNA sequencers

D

VNTR

Question 175: Palette 175/394

Allen MCQ

In density gradient centrifugation, the bulk DNA forms while satellite DNA forms

A

Major peak; Minor peak

B

Minor peak; Major peak

C

Major peak; Major peak

D

Minor peak; Minor peak

Question 176: Palette 176/394

Allen MCQ

Which step is not correct in DNA finger printing ?

A

Isolation of DNA

B

Digestion of DNA by DNA ligase enzyme

C

Separation of DNA by electrophoresis

D

Hybridisation using labelled VNTR probe

Question 177: Palette 177/394

Allen MCQ

DNA fingerprinting method is very useful for:

A

DNA tests for identity & relationships

B

Forensic studies

C

Polymorphism studies

D

All of the above

Question 178: Palette 178/394

Allen MCQ

Commonly used vectors for human genome sequencing are :-

A

T-DNA

B

BAC and YAC

C

Expression Vectors

D

T/A Cloning Vectors

Question 179: Palette 179/394

Allen MCQ

In sea urchin DNA, which is double stranded, 17% of the bases were shown to be cytosine. The percentages of the other three bases expected to be present in this DNA are :-

A

G 17%, A 16.5%, T 32.5%

B

G 17%, A 33%, T 33%

C

G 8.5%, A 50%, T 24.5%

D

G 34%, A 24.5%, T 24.5%

Question 180: Palette 180/394

Allen MCQ

Gene regulation governing lactose operon of E.coli that involves the lac I gene product is :-

A

Negative and inducible because repressor protein prevents transcription

B

Negative and repressible because repressor protein prevents transcription

C

Feedback inhibition because excess of β-galactosidasecanswitchoff transcription

D

Positive and inducible because it can be induced by lactose BMI209

Question 181: Palette 181/394

Allen MCQ

The movement of a gene from one linkage group to another is called :-

A

Duplication

B

Translocation

C

Crossing over

D

Inversion

Question 182: Palette 182/394

Allen MCQ

Which of the following biomolecules does have a phosphodiester bond?

A

Nucleic acids in a nucleotide

B

Fatty acids in a diglyceride

C

Monosaccharides in a polysaccharide

D

Amino acids in a polypeptide

Question 183: Palette 183/394

Allen MCQ

Which one of the following is not applicable to RNA?

A

Chargaff's rule

B

Complementary base pairing

C

5' phosphoryl and 3' hydroxyl ends

D

Heterocyclic nitrogenous bases

Question 184: Palette 184/394

Allen MCQ

Satellite DNA is important because it :-

A

Codes for enzymes needed for DNA replication

B

Codes for proteins needed in cell cycle

C

Shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children

D

Does not code for proteins and is same in all members of the population BMI213

Question 185: Palette 185/394

Allen MCQ

Identify the correct order of organisation of genetic material from largest to smallest :-

A

Chromosome, genome, nucleotide, gene

B

Chromosome, gene, genome, nucleotide

C

Genome, chromosome, nucleotide, gene

D

Genome, chromosome, gene, nucleotide BMI214

Question 186: Palette 186/394

Allen MCQ

Which of the following is required as inducer(s) for the expression of Lac operon?

A

Glucose

B

Galactose

C

Lactose

D

Lactose and galactose

Question 187: Palette 187/394

Allen MCQ

A complex of ribosomes attached to a single strand of RNA is known as :-

A

Polysome

B

Polymer

C

Polypeptide

D

Okazaki fragment

Question 188: Palette 188/394

Allen MCQ

Which of the following is not required for any of the techniques of DNA fingerprinting available at present?

A

Polymerase chain reaction

B

Zinc finger analysis

C

Restriction enzymes

D

DNA-DNA hybridization

Question 189: Palette 189/394

Allen MCQ

Which one of the following is the starter codon?

A

AUG

B

UGA

C

UAA

D

UAG

Question 190: Palette 190/394

Allen MCQ

Taylor conducted the experiment to prove semiconservative mode of chromosome replication on : -

A

Drosophila melanogaster

B

E. coli

C

Vinca rosea

D

Vicia faba

Question 191: Palette 191/394

Allen MCQ

The equivalent of a structural gene is :-

A

Operon

B

Recon

C

Muton

D

Cistron

Question 192: Palette 192/394

Allen MCQ

Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria?

A

23 S rRNA

B

5.8 S rRNA

C

5 S rRNA

D

18 S rRNA

Question 193: Palette 193/394

Allen MCQ

A non-proteinaceous enzyme is :-

A

Ligase

B

Deoxyribonuclease

C

Lysozyme

D

Ribozyme

Question 194: Palette 194/394

Allen MCQ

A molecule that can act as a genetic material must fulfil the traits given below, except :-

A

It should be unstable structurally and chemically

B

It should provide the scope for slow changes that are required for evolution

C

It should be able to express itself in the form of 'Mendelian characters'

D

It should be able to generate its replica BMI223

Question 195: Palette 195/394

Allen MCQ

DNA-dependent RNA polymerase catalyses transcription on one strand of the DNA which is called the :-

A

Alpha strand

B

Antistrand

C

Template strand

D

Coding strand

Question 196: Palette 196/394

Allen MCQ

The mechanism that causes a gene to move from one linkage group to another is called:-

A

Translocation

B

Crossing-over

C

Inversion

D

Duplication

Question 197: Palette 197/394

Allen MCQ

The final proof for DNA as the genetic material came from the experiments of :-

A

Hershey and Chase

B

Avery, McLeod and McCarty

C

Hargobind Khorana

D

Griffith

Question 198: Palette 198/394

Allen MCQ

DNA fragments are:-

A

Negatively charged

B

Neutral

C

Either positively or negatively charged depending on their size

D

Positively charged

Question 199: Palette 199/394

Allen MCQ

If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?

A

11

B

33

C

333

D

1

Question 200: Palette 200/394

Allen MCQ

During DNA replication, Okazaki fragments are used to elongate:-

A

The lagging strand towards replication fork.

B

The leading strand away from replication fork.

C

The lagging strand away from the replication fork.

D

The leading strand towards replication fork

Question 201: Palette 201/394

Allen MCQ

Which of the following RNAs should be most abundant in animal cell ?

A

t-RNA

B

m-RNA

C

mi-RNA

D

r-RNA

Question 202: Palette 202/394

Allen MCQ

What is the criterion for DNA fragments movement on agarose gel during gel electrophoresis ?

A

The smaller the fragment size, the farther it moves

B

Positively charged fragments move to farther end

C

Negatively charged fragments do not move

D

The larger the fragment size, the farther it moves

Question 203: Palette 203/394

Allen MCQ

DNA replication in bacteria occurs:-

A

Within nucleolus

B

Prior to fission

C

Just before transcription

D

During S phase

Question 204: Palette 204/394

Allen MCQ

Spliceosomes are not found in cells of:-

A

Fungi

B

Animals

C

Bacteria

D

Plants

Question 205: Palette 205/394

Allen MCQ

The association of histone H₁ with a nucleosome indicates:-

A

DNA replication is occurring.

B

The DNA is condensed into a Chromatin Fibre.

C

The DNA double helix is exposed.

D

Transcription is occurring.

Question 206: Palette 206/394

Allen MCQ

The experimental proof for semiconservative replication of DNA was first shown in a:-

A

Fungus

B

Bacterium

C

Plant

D

Virus

Question 207: Palette 207/394

Allen MCQ

Select the correct match :-

A

Alec Jeffreys - Streptococcus pneumoniae

B

Alfred Hershey and – TMV Martha Chase

C

Matthew Meselson – Pisum sativum and F. Stahl

D

Francois Jacob and – Lac operon Jacques Monod

Question 208: Palette 208/394

Allen MCQ

Select the correct Match :-

A

Ribozyme – Nucleic acid

B

F2 × Recessive parent – Dihybrid cross

C

T.H. Morgan — Transduction

D

G. Mendel — Transformation

Question 209: Palette 209/394

Allen MCQ

AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA ?

A

AGGUAUCGCAU

B

UGGTUTCGCAT

C

ACCUAUGCGAU

D

UCCAUAGCGUA

Question 210: Palette 210/394

Allen MCQ

All of the following are part of an operon except :-

A

an operator

B

structural genes

C

an enhancer

D

a promoter

Question 211: Palette 211/394

Allen MCQ

Purines found both in DNA and RNA are :-

A

Adenine and thymine

B

Adenine and guanine

C

Guanine and cytosine

D

Cytosine and thymine

Question 212: Palette 212/394

Allen MCQ

Under which of the following conditions will there be no change in the reading frame of following mRNA ? 5'AACAGCGGUGCUAUU3'

A

Insertion of G at 5th position

B

Deletion of G from 5th position

C

Insertion of A and G and 4th and 5th positions respectively

D

Deletion of GGU from 7th, 8th and 9th positions

Question 213: Palette 213/394

Allen MCQ

Expressed Sequence Tags (ESTs) refers to :-

A

Genes expressed as RNA

B

Polypeptide expression

C

DNA polymorphism

D

Novel DNA sequences

Question 214: Palette 214/394

Allen MCQ

Match the following genes of the Lac operon with their respective products :-

Column-I	Column-II
(a) igene (b) z gene (c) a gene (d) y gene	(i) β-galactosidase (ii) Permease (iii) Repressor (iv) Transacetylase

A

a-i, b-iii,c-ii,d-iv

B

a-iii,b-i, c-ii, d-iv

C

a-iii,b-i, c-iv, d-ii

D

a-iii,b-iv,c-i, d-ii

Question 215: Palette 215/394

Allen MCQ

What will be the sequence of mRNA produced by the following stretch of DNA? 3'ATGCATGCATGCATG5' Template strand 5'TACGTACGTACGTAC3' Coding strand

A

3'AUGCAUGCAUGCAUG5'

B

5'UACGUACGUACGUAC3'

C

3'UACGUACGUACGUAC5'

D

5'AUGCAUGCAUGCAUG3

Question 216: Palette 216/394

Allen MCQ

Match the following RNA polymerase with their transcribed products :-

Column-I	Column-II
(a) RNA polymerase I (b) RNA polymerase II (c) RNA polymerase III	(i) tRNA (ii) rRNA (iii) hnRNA

A

a-i, b-iii,c-ii

B

a-i, b-ii, c-iii

C

a-ii,b-iii,c-i

D

a-iii,b-ii,c-i

Question 217: Palette 217/394

Allen MCQ

From the following, identify the correct combination of salient features of Genetic Code :-

A

Universal, Non-ambiguous, Overlapping

B

Degenerate, Overlapping, Comma less

C

Universal, Ambiguous, Degenerate

D

Degenerate, Non-overlapping, Nonambiguous

Question 218: Palette 218/394

Allen MCQ

Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage ?

A

Beadle and Tatum

B

Meselson and Stahl

C

Hershey and Chase

D

Jacob and Monod

Question 219: Palette 219/394

Allen MCQ

In the process of transcription in Eukaryotes, the RNA polymerase I transcribes :-

A

mRNA with additional processing, capping and tailing

B

tRNA, 5 S rRNA and snRNAs

C

rRNAs–28 S, 18 S and 5.8 S

D

Precursor of mRNA, hnRNA

Question 220: Palette 220/394

Allen MCQ

What initiation and termination factors are involved in transcription in prokaryotes ?

A

σ and ρ, respectively

B

α and β, respectively

C

β and γ, respectively

D

α and σ, respectively

Question 221: Palette 221/394

Allen MCQ

Which of the following statements is correct?

A

Adenine does not pair with thymine

B

Adenine pairs with thymine through two H-bonds

C

Adenine pairs with thymine through one H-bond

D

Adenine pairs with thymine through three H-bonds

Question 222: Palette 222/394

Allen MCQ

If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is $6 . 6 \times 1 0 ^ { 9 }$ bp, then the length of the DNA is approximately: -

A

2.7 meters

B

2.0 meters

C

2.5 meters

D

2.2 meters

Question 223: Palette 223/394

Allen MCQ

Name the enzyme that facilitates opening of DNA helix during transcription: -

A

RNA polymerase

B

DNA ligase

C

DNA helicase

D

DNA polymerase

Question 224: Palette 224/394

Allen MCQ

The first phase of translation is :-

A

Recognition of an anti-codon

B

Binding of mRNA to ribosome

C

Recognition of DNA molecule

D

Aminoacylation of tRNA

Question 225: Palette 225/394

Allen MCQ

In gel electrophoresis, separated DNA fragments can be visualized with the help of

A

Ethidium bromide in infrared radiation

B

Acetocarmine in bright blue light

C

Ethidium bromide in UV radiation

D

Acetocarmine in UV radiation

Question 226: Palette 226/394

Allen MCQ

The term 'Nuclein' for the genetic material was used by :-

A

Franklin

B

Miescher

C

Chargaff

D

Mendel

Question 227: Palette 227/394

Allen MCQ

In the polynucleotide chain of DNA, a nitrogenous base is linked to the -OH of:-

A

2'C pentose sugar

B

3'C pentose sugar

C

5'C pentose sugar

D

1'C pentose sugar

Question 228: Palette 228/394

Allen MCQ

Which is the basis of genetic mapping of human genome as well as DNA finger printing

A

Polymorphism in DNA sequence

B

Single nucleotide polymorphism

C

Polymorphism in hnRNA sequence

D

Polymorphism in RNA sequence

Question 229: Palette 229/394

Allen MCQ

Complete the flow chart on central dogma:-
(a) DNA ──(b) Transcription──→ mRNA ──(c) Translation──→ (d) Protein

A

(a)-Replication; (b)-Transcription; (c)-Transduction; (d)-Protein

B

(a)-Translation; (b)-Replication; (c)-Transcription; (d)-Transduction

C

(a)-Replication; (b)-Transcription; (c)-Translation; (d)-Protein

D

(a)-Transduction; (b)-Translation; (c)-Replication; (d)-Protein

Question 230: Palette 230/394

Allen MCQ

Identify the correct statement:-

A

In capping, methyl guanosine triphosphate is added to the 3' end of hnRNA.

B

RNA polymerase binds with Rho factor to terminate the process of transcription in bacteria.

C

The coding strand in a transcription unit is copied to an mRNA.

D

Split gene arrangement is characteristic of prokaryotes.

Question 231: Palette 231/394

Allen MCQ

What is the role of RNA polymerase IIl in the process of transcription in eukaryotes?

A

Transcribes rRNAs (28S, 18S and 5.8S)

B

Transcribes tRNA, 5S rRNA and snRNA

C

Transcribes precursor of mRNA

D

Transcribes only snRNAs

Question 232: Palette 232/394

Allen MCQ

DNA fingerprinting involves identifying differences in some specific regions in DNA sequence, called as :-

A

Satellite DNA

B

Repetitive DNA

C

Single nucleotides

D

Polymorphic DNA

Question 233: Palette 233/394

Allen MCQ

Which is the “Only enzyme" that has "Capability" tocatalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?

A

DNA dependent DNA polymerase

B

DNA dependent RNA polymerase

C

DNA Ligase

D

DNase

Question 234: Palette 234/394

Allen MCQ

Which of the following RNAs is not required for the synthesis of protein?

A

mRNA

B

tRNA

C

rRNA

D

siRNA

Question 235: Palette 235/394

Allen MCQ

If Adenine makes 30% of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?

A

T :20; G:30; C:20

B

T:20; G:20; C:30

C

T :30; G:20; C:20

D

T:20; G:25; C:25

Question 236: Palette 236/394

Allen MCQ

Read the following statements and choose the set of correct statements: -
(a) Euchromatin is loosely packed chromatin.
(b) Heterochromatin is transcriptionally active
(c) Histone octamer is wrapped by negatively charged DNA in nucleosome.
(d) Histones are rich in lysine and arginine.
(e) A typical nucleosome contains 400 bp of DNA helix.

A

(a), (c), (d) Only

B

(b), (e) Only

C

(a), (c), (e) Only

D

(b), (d), (e) Only

Question 237: Palette 237/394

Allen MCQ

DNA polymorphism forms the basis of:-

A

DNA finger printing

B

Both genetic mapping and DNA finger printing

C

Translation

D

Genetic mapping

Question 238: Palette 238/394

Allen MCQ

The process of translation of mRNA to proteins begins as soon as :-

A

The larger subunit of ribosome encounters mRNA.

B

Both the subunits join together to bind with mRNA.

C

The tRNA is activated and the larger subunit of ribosome encounters mRNA.

D

The small subunit of ribosome encounters mRNA.

Question 239: Palette 239/394

Allen MCQ

If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as:-

A

Gene mapping

B

Expressed sequence tags

C

Bioinformatics

D

Sequence annotation BMI269

Question 240: Palette 240/394

Allen MCQ

In an E. coli strain i gene gets mutated and its product can not bind the inducer molecule. If growth medium is provided with lactose, what will be the outcome?

A

z, y, a genes will be transcribed

B

z, y, a genes will not be translated

C

RNA polymerase will bind the promoter region

D

Only z gene will get transcribed

Question 241: Palette 241/394

Allen MCQ

If the length of a DNA molecule is 1.1 metres, what will be the approximate number of base pairs ?

A

$6 . 6 \times 1 0 ^ { 9 } \mathsf { b p }$

B

$3 . 3 \times 1 0 ^ { 6 } \mathsf { b p }$

C

$6 . 6 \times 1 0 ^ { 6 } \mathsf { b p }$

D

$3 . 3 \times 1 0 ^ { 9 } \mathrm { b p }$

Question 242: Palette 242/394

Allen MCQ

Ten E. coli cells with15N - dsDNA are incubated in medium containing 14N nucleotide. After 60 minutes, how many E. coli cells will have DNA totally free from 15N :

A

40 cells

B

60 cells

C

80 cells

D

20 cells

Question 243: Palette 243/394

Allen Match the Columns

Match Column-I with Column-II :

Column-I	Column-II
(a) Bacteriophage φ × 174 (b) Bacteriophage lambda (c) Escherichia coli (d) Haploid content of human DNA	(i) 48502 base pairs (ii) 5386 nucleotides (iii) 3.3 × 10⁹ base pairs (iv) 4.6 × 10⁹ base pairs

A

(a) - (iii),(b) - (ii), (c)-(i), (d)-(iv)

B

(a) - (iv), (b) - (iii),(c)-(ii),(d)-(i)

C

(a) - (iv), (b) - (i), (c)-(iii),(d)-(ii)

D

(a) - (iii),(b) - (i), (c)-(iv), (d)-(ii)

Question 244: Palette 244/394

Allen MCQ

Given below are two statements: Statement I :- DNA polymerases catalyse polymerisation only in one direction, that is $5 ^ { \prime } 3 ^ { \prime }$ Statement II :- During replication of DNA, on one strand the replication is continuous while on the other strand it is discontinuous. In the light of the above statements, choose the correct answer from the options given below :

A

Both Statement I and Il are correct

B

Both Statement I and II are incorrect

C

Statement I is correct but Statement II is incorrect

D

Statement I is incorrect but Statement II is correct

Question 245: Palette 245/394

Allen Match the Columns

Match Column-I with Column-II :-

Column-I	Column-II
(a) Bacteriophage φ × 174 (b) Bacteriophage lambda (c) Escherichia coli (d) Haploid content of human DNA	(i) 48502 base pairs (ii) 5386 nucleotides (iii) 3.3 × 10⁹ base pairs (iv) 4.6 × 10⁹ base pairs

A

(a) - (i), (b) - (ii), (c) - (iii),(d) - (iv)

B

(a) - (ii),(b) - (iv), (c) - (i), (d) - (iii)

C

(a) - (ii),(b) - (i), (c) - (iv), (d) - (iii

D

(a) - (i), (b) - (ii), (c) - (iν),(d) - (iii)

Question 246: Palette 246/394

Allen MCQ

If DNA contained sulphur instead of phosphorus and proteins contained phosphorus instead of sulfur, what would have been the outcome of Hershey and Chase experiment?

A

No radioactive sulfur in bacterial cells

B

Both radioactive sulfur and phosphorus in bacterial cells

C

Radioactive sulfur in bacterial cells

D

Radioactive phosphorus in bacterial Cells

Question 247: Palette 247/394

Allen MCQ

In lac operon, z gene codes for :-

A

β-galactosidase

B

Permease

C

Repressor

D

Transacetylase BMI277

Question 248: Palette 248/394

Allen MCQ

Unequivocal proof that DNA is the genetic material was first proposed by

A

Alfred Hershey and Martha Chase

B

Avery, MacLeod and McCarthy

C

Wilkins and Franklin

D

Frederick Griffith

Question 249: Palette 249/394

Allen MCQ

Among eukaryotes, replication of DNA takes place in -

A

S phase

B

G₁ phase

C

G₂ phase

D

M phase

Question 250: Palette 250/394

Allen MCQ

What is the role of RNA polymerase III in the process of transcription in Eukaryotes ?

A

Transcription of tRNA, 5S rRNA and snRNA

B

Transcription of precursor of mRNA

C

Transcription of only snRNAs

D

Transcription of rRNAs (28S, 18S and 5.8S)

Question 251: Palette 251/394

Allen MCQ

Expressed Sequence Tags (ESTs) refers to

A

All genes that are expressed as proteins.

B

All genes whether expressed or unexpressed.

C

Certain important expressed genes.

D

All genes that are expressed as RNA.

Question 252: Palette 252/394

Allen MCQ

How many different proteins does the ribosome consist of?

A

60

B

40

C

20

D

80

Question 253: Palette 253/394

Allen Match the Columns

Match Column-I with Column-II.

Column-I	Column-II
(a) Gene 'a' (b) Gene 'y' (c) Gene 'i' (d) Gene 'z'	(i) β-galactosidase (ii) Transacetylase (iii) Permease (iv) Repressor protein

A

a-ii, b-iii,c-iv,d-i

B

a-iii,b-iv,c-i, d-ii

C

a-iii,b-i, c-iv,d-ii

D

a-ii, b-i, c-iv,d-iii

Question 254: Palette 254/394

Allen MCQ

Given below are two statements: Statement I: RNA mutates at a faster rate. Statement II : Viruses having RNA genome and shorter life span mutate and evolve faster. In the light of the above statements, choose the correct answer from the options given below :

A

Both Statement I and II are false.

B

Statement I is true but Statement Il is false.

C

Statement I false but Statement II is true.

D

Both Statement I and Il are true

Question 255: Palette 255/394

Allen MCQ

Give below are two statements. Statement-I : In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid. Statement-Il : In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome. In the light of the above statements, choose the correct answer from the options given below :

A

Both Statement I and Statement Il are false.

B

Statement I is correct but Statement II is false.

C

Statement I incorrect but Statement II is true.

D

Both Statement I and Statement II are true.

Question 256: Palette 256/394

Allen MCQ

Which one of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is as follows 5' AUCGAUCGAUCGAUCGAUCGAUCG AUCG 3'?

A

3' UAGCUAGCUAGCUAGCUA GCUAGCUAGC 5'

B

5' ATCGATCGATCGATCGATCG ATCGATCG 3'

C

3' ATCGATCGATCGATCGATCG ATCGATCG 5'

D

5' UAGCUAGCUAGCUAGCUAGC UAGCUAGC 3'

Question 257: Palette 257/394

Allen MCQ

The last chromosome sequenced in Human Genome Project was :-

A

Chromosome 6

B

Chromosome 1

C

Chromosome 22

D

Chromosome 14

Question 258: Palette 258/394

Allen MCQ

Name the component that binds to the operator region of an operon and prevents RNA polymerase from transcribing the operon.

A

Promotor

B

Regulator protein

C

Repressor protein

D

Inducer

Question 259: Palette 259/394

Allen MCQ

Given below are two statements : Statement-I: The process of copying genetic information from one strand of the DNA into RNA is termed as transcription. Statement-II: A transcription unit in DNA is defined primarily by the three regions in the DNA i.e., a promoter, the structural gene and a terminator. In the light of the above statements, choose the correct answer from the options given below :

A

Statement I is true but Statement II is false

B

Statement I is false but Statement II is true

C

Both Statement I and II are true

D

Both Statement I and Il are false

Question 260: Palette 260/394

Allen MCQ

Which scientist conducted an experiment with ³²P and ³⁵S labelled phages for demonstrating that DNA is the genetic material?

A

James D. Watson and F.H.C. Crick

B

A.D. Hershey and M.J. Chase

C

F. Griffith

D

O.T. Avery, C.M. MacLeod and M. McCarty

Question 261: Palette 261/394

Allen MCQ

Statement-I: RNA being unstable, mutate at a faster rate. Statement-II: RNA can directly code for synthesis of proteins hence can easily express the characters. In the light of the above statements, choose the correct answer from the options given below:

A

Statement I is true but Statement II is false

B

Statement I is false but Statement II is true

C

Both Statement I and Statement II are true

D

Both Statement I and Statement II are false

Question 262: Palette 262/394

Allen MCQ

Select the correct statements about sickle cell anaemia.
(A) There is a change in gene for beta globin.
(B) In the beta globin, there is valine in the place of Lysine.
(C) It is an example of point mutation.
(D) In the normal gene U is replaced by A.

A

(B), (C) and (D) only

B

(B) and (D) only

C

(A), (B) and (D) only

D

(A) and (C) only

Question 263: Palette 263/394

Allen MCQ

Which one of the following acts as an inducer for lac operon?

A

Sucrose

B

Lactose

C

Glucose

D

Galactose

Question 264: Palette 264/394

Allen MCQ

With reference to Hershey and Chase experiments, select the correct statements.
(A) Viruses grown in the presence of radioactive phosphorus contained radioactive DNA.
(B) Viruses grown on radioactive sulphur contained radioactive proteins.
(C) Viruses grown on radioactive phosphorus contained radioactive protein.
(D) Viruses grown on radioactive sulphur contained radioactive DNA.
(E) Viruses grown on radioactive protein contained radioactive DNA.
Choose the most appropriate answer from the options given below:

A

(D) and (E) only

B

(A) and (B) only

C

(A) and (C) only

D

(B) and (D) only

Question 265: Palette 265/394

Allen MCQ

The salient features of genetic code are:
(A) The code is palindromic.
(B) UGA acts as initiator codon.
(C) The code is unambiguous and specific.
(D) The code is nearly universal.
Choose the most appropriate answer from the options given below:

A

(A) and (D) only

B

(B) and (C) only

C

(A) and (B) only

D

(C) and (D) only

Question 266: Palette 266/394

Allen MCQ

The lactose present in the growth medium of bacteria is transported to the cell by the action of :-

A

Beta-galactosidase

B

Acetylase

C

Permease

D

Polymerase

Question 267: Palette 267/394

Allen MCQ

A transcription unit in DNA is defined primarily by the three regions in DNA and these are with respect to upstream and down stream end;

A

Repressor, Operator gene, Structural gene

B

Structural gene, Transposons, Operator gene

C

Inducer, Repressor, Structural gene

D

Promotor, Structural gene, Terminator

Question 268: Palette 268/394

Allen Match the Columns

Match Column-I with Column-II.

Column-I	Column-II
(a) Frederick Griffith (b) François Jacob & Jacques Monod (c) Har Gobind Khorana (d) Meselson & Stahl	(i) Genetic code (ii) Semi-conservative mode of DNA replication (iii) Transformation (iv) Lac operon

A

a-iii, b-ii, c-i, d-iv

B

a-iii, b-iv, c-i, d-ii

C

a-ii, b-iii, c-iv, d-i

D

a-iv, b-i, c-ii, d-iii

Question 269: Palette 269/394

Allen MCQ

Which of the following statement is correct regarding the process of replication in E.coli?

A

The DNA dependent DNA polymerase catalyses polymerization in one direction that is 3' → 5'

B

The DNA dependent RNA polymerase catalyses polymerization in one direction, that is 5' → 3'

C

The DNA dependent DNA polymerase catalyses polymerization in 5' → 3' as well as 3' → 5' direction

D

The DNA dependent DNA polymerase catalyses polymerization in 5' → 3' direction.

Question 270: Palette 270/394

Allen MCQ

Which one is the correct product of DNA dependent RNA polymerase to the given template ? 3'TACATGGCAAATATCCATTCA5'

A

5'AUGUACCGUUUAUAGGUAAGU3'

B

5'AUGUAAAGUUUAUAGGUAAGU3'

C

5'AUGUACCGUUUAUAGGGAAGU3'

D

5'ATGTACCGTTTATAGGTAAGT3'

Question 271: Palette 271/394

Allen Match the Columns

Match Column-I with Column-II.

Column-I	Column-II
(a) RNA polymerase III (b) Termination of transcription (c) Splicing of exons (d) TATA box	(i) snRNPs (ii) Promotor (iii) Rho factor (iv) snRNAs, tRNA

A

a-ii, b-iv, c-i, d-iii

B

a-iii,b-ii, c-iv,d-i

C

a-iii,b-iv, c-i, d-ii

D

a-iv, b-iii,c-i, d-ii

Question 272: Palette 272/394

Allen MCQ

In a chromosome, there is a specific DNA sequence responsible for initiating replication. It is called as :-

A

recognition sequence

B

cloning site

C

restriction site

D

ori site

Question 273: Palette 273/394

Allen MCQ

Given below are two statements regarding RNA polymerase in prokaryotes. Statement-I: In prokaryotes, RNA polymerase is capable of catalysing the process of elongation during transcription. Statement-II: RNA polymerase associate transiently with 'Rho' factor to initiate transcription. In the light of the above statements, choose the correct answer from the options given below :-

A

Statement I is true but Statement Il is false

B

Statement I is false but Statement Il is true

C

Both Statement I and Statement Il are true

D

Both Statement I and Statement Il are false

Question 274: Palette 274/394

Allen MCQ

Which of the following is a nucleotide ?

A

Uridine

B

Adenylic acid

C

Guanine

D

Guanosine

Question 275: Palette 275/394

Allen MCQ

Statement I: In eukaryotes there are three RNA polymerases in the nucleus in addition to the RNA polymerase found in the organelles. Statement-II: AlI the three RNA polymerases in eukaryotic nucleus have different roles. In the light of the above statements, choose the correct answer from the options given below:-

A

Statement l is true but Statement Il is false

B

Statement I is false but Statement Il is true

C

Both Statement I and Statement Il are true

D

Both Statement I and Statement Il are false

Question 276: Palette 276/394

Allen Match the Columns

Match Column-I with Column-II.

Column-I	Column-II
(a) Histones (b) Nucleosome (c) Euchromatin (d) Heterochromatin	(i) Loosely packed chromatin (ii) Densely packed chromatin (iii) Positively charged basic proteins (iv) DNA wrapped around histone octamer

A

a-iv, b-iii, c-ii, d-i

B

a-iii, b-i, c-iv, d-ii

C

a-ii, b-iii, c-iv, d-i

D

a-iii, b-iv, c-i, d-ii

Question 277: Palette 277/394

Allen MCQ

Statement-I: In the lac operon, the z gene codes for beta-galactosidase which is primarily responsible for the hydrolysis of lactose into galactose and glucose. Statement-II: In addition to lactose, glucose or galactose can also induce lac operon. In the light of the above statements, choose the correct answer from the options given below :

A

Statement I is true but Statement Il is false

B

Statement I is false but Statement Il is true

C

Both Statement I and Statement Il are true

D

Both Statement I and Statement Il are false

Question 278: Palette 278/394

Allen MCQ

Aneuploidy is a chromosomal disorder where chromosome number is not the exact copy of its haploid set of chromosomes, due to:
(a) Substitution
(b) Addition
(c) Deletion
(d) Translocation
(e) Inversion

A

C and D only

B

D and E only

C

A and B only

D

B and C only

Question 279: Palette 279/394

Allen MCQ

Match the following :-

Column-I	Column-II
(a) φ×174 (b) Lambda phage (c) E.coli (d) Human somatic cell	(i) 48502 bp (ii) 5386 Nucleotides (iii) 6.6 x 109 bp (iv) 4.6 x 10⁶ bp

A

a–(i), b−(ii),c–(iv), d−(iii)

B

a–(ii),b–(i), c–(iv), d−(iii)

C

a−(i), b–(ii),c–(iii),d−(iv)

D

a–(iv),b–(iii),c–(ii),d−(i)

Question 280: Palette 280/394

Allen MCQ

Which of the following pyrimidine base is common in both DNA and RNA:-

A

Adenine

B

Guanine

C

Cytosine

D

Thymine

Question 281: Palette 281/394

Allen MCQ

In nucleoside which of the following bond exists between sugar and nitrogenous base:-

A

Phosphodiester bond

B

Hydrogen bond

C

Phosphoester bond

D

N-glycosidic bond

Question 282: Palette 282/394

Allen MCQ

By which of the following bond phosphoric acid remain linked with 5' carbon of sugar in one nucleotide:-

A

Phosphoester bond

B

Phosphodiester bond

C

N-Glycosidic bond

D

Hydrogen bond

Question 283: Palette 283/394

Allen MCQ

The backbone in a polynucleotide chain is formed due to:-

A

Sugars and nitrogenous bases

B

Phosphates and nitrogenous base

C

Nitrogenous bases and histones

D

Sugar and phosphates

Question 284: Palette 284/394

Allen MCQ

In RNA, every nucleotide residue has an additional - OH group at which of the following position?

A

2' position of deoxyribose

B

1' position of ribose sugar

C

3' position of ribose sugar

D

2' position of ribose sugar

Question 285: Palette 285/394

Allen MCQ

DNA as an acidic substance present in nucleus was first identified by:-

A

Wilkins and Franklin

B

Watson and Crick

C

Friedrich Miescher

D

Altmann

Question 286: Palette 286/394

Allen MCQ

Double helix model of DNA proposed by Watson and Crick was based on:-

A

X-ray diffraction data of Miescher

B

X-ray crystallography data of Wilkins and Franklin

C

X-ray diffraction data of Watson and Crick

D

X-ray diffraction data of Chargaff

Question 287: Palette 287/394

Allen MCQ

Regarding to features of double helix structure of DNA which of the following is wrong?

A

Two polynucleotide chains have antiparallel polarity

B

The bases in two strands are paired through phosphodiester bonds

C

Adenine form two hydrogen bonds with thymine

D

The pitch of the helix is 3.4 nm

Question 288: Palette 288/394

Allen MCQ

In addition to hydrogen bonding which of the following feature confers stability to helical structure?

A

Phosphodiester bond

B

Pairing between one purine and one pyrimidine

C

Glycosidic linkage between sugar and nitrogenous base

D

The plane of one base pair stacks over the other

Question 289: Palette 289/394

Allen MCQ

Which of the following is responsible for constantdistancebetween two polynucleotide chains in DNA?

A

Antiparallel polarity of two polynucleotide strands

B

Hydrogen bonding

C

Pairing between one purine and one pyrimidine

D

All the above

Question 290: Palette 290/394

Allen MCQ

Phosphoric acid remain associated with which of the following carbon of sugar in a nucleotide ?

A

$1 ^ { \mathsf { s t } }$

B

$3 ^ { \mathsf { r d } }$

C

$4 ^ { \mathrm { t h } }$

D

$5 ^ { \mathrm { t h } }$

Question 291: Palette 291/394

Allen MCQ

If there are $3 . 3 \times 1 0 ^ { 9 }$ bp present in genome, then what would be the length of the DNA of any somatic cell?

A

1.1 meter

B

2.2 meter

C

3.3 meter

D

6.6 meter

Question 292: Palette 292/394

Allen MCQ

Positive charge and basic nature of histone is due to abundance of:-

A

Lysine and tryptophan

B

Arginine & threonine

C

Lysine and arginine

D

Tryptophan and threonine

Question 293: Palette 293/394

Allen MCQ

Negative charge of DNA is due to which of the following constituent:-

A

Sugar

B

Nitrogenous base

C

Phosphoric acid

D

Hydroxyl group (-OH) present on sugar BMI292

Question 294: Palette 294/394

Allen MCQ

A typical nucleosome contains how much amount of DNA?

A

100 bp

B

146 bp

C

200 bp

D

346 bp

Question 295: Palette 295/394

Allen MCQ

In a mammalian somatic cell how many nucleosomes are present?

A

$6 . 6 \times 1 0 ^ { 9 }$

B

$3 . 3 \times 1 0 ^ { 9 }$

C

$3 . 3 \times 1 0 ^ { 7 }$

D

$3 . 3 \times 1 0 ^ { 5 }$

Question 296: Palette 296/394

Allen MCQ

Which of the following is actual sequence of packaging of DNA in eukaryotic cells?

A

DNA → Chromatin → Nucleosome → Chromosome

B

DNA → Nucleosome → Chromosome → Chromatin

C

DNA → Nucleosome → Chromatin → Chromosome

D

DNA → Chromosome → Chromatin → Nucleosome

Question 297: Palette 297/394

Allen MCQ

The packaging of chromatin at higher level requires additional set of proteins that is known as:-

A

Histone proteins

B

NHC proteins

C

Homeotic proteins

D

Domain proteins

Question 298: Palette 298/394

Allen MCQ

Regarding to Meselson and Stahl experiment for semi conservative nature of DNA replication select out the wrong statement: -

A

15N of 15NH₄Cl was incorporated in DNA and other compounds

B

15N & 14N can be differentiate on the basis of radioactive activity

C

Heavy and normal DNA molecules could be distinguished by CsCl density gradient centrifugation

D

15N used in 15NH₄Cl was not a radioactive isotope

Question 299: Palette 299/394

Allen MCQ

If normal E. coli is allow to grow for 80 minutes in 15NH₄Cl medium then what would be the proportion of hybrid and heavy density DNA molecules:-

A

1:7

B

7:1

C

14:2

D

1:4

Question 300: Palette 300/394

Allen MCQ

Semiconservative replication of DNA in chromosomes was proved by:-

A

Meselson & Stahl by using1⁵NH₄Cl

B

Taylor by using 1⁵NH₄Cl

C

Meselson & Stahl by using tritiated thymidine

D

Taylor by using tritiated thymidine

Question 301: Palette 301/394

Allen MCQ

How much duration of time required for replication of 4.6 x 10⁶ bp in E. coli?

A

83 minutes

B

18 minutes

C

2 minutes

D

3hrs

Question 302: Palette 302/394

Allen MCQ

During replication large amount of energy get exhausted. The source of this energy is

A

Deoxyribonucleotide triphosphate

B

Deoxyribonucleoside monophosphate

C

Deoxyribonucleoside triphosphate

D

Both (1) and (2)

Question 303: Palette 303/394

Allen MCQ

Regarding to direction of DNA replication select out the correct one :-

A

5' → 3' Template – continuous synthesis

B

3' → 5' Template - discontinuous synthesis

C

3' → 5' Template – continuous synthesis

D

5' → 3' Template – synthesis of leading strand

Question 304: Palette 304/394

Allen MCQ

Which of the following diagram of replication fork is correct?

A

B

C

D

Question 305: Palette 305/394

Allen MCQ

Which of the following feature of RNA make it labile and easily degradable?

A

Single stranded nature

B

2'-OH group on ribose sugar

C

Phosphodiester bond

D

Absence of Hydrogen bond

Question 306: Palette 306/394

Allen MCQ

Regarding to RNA which of the following feature is wrong?

A

Catalytic property

B

Labile and easily degradable

C

Absence of thymine

D

Presence of methylated uracil

Question 307: Palette 307/394

Allen MCQ

Which of the following reason is suitable to explain that RNA is best for expression of characters?

A

It shows catalytic properties

B

Presence of 2'-OH group on ribose sugar

C

It can directly code for the synthesis of protein

D

Presence of uracil

Question 308: Palette 308/394

Allen MCQ

An adapter molecule that would on one hand read the code and on the other hand would bind to specific amino acids is:-

A

mRNA

B

rRNA

C

tRNA

D

hnRNA

Question 309: Palette 309/394

Allen MCQ

Which of the following r-RNA show structural as well as catalytic role in bacteria

A

16S rRNA

B

23S rRNA

C

5S rRNA

D

28S rRNA

Question 310: Palette 310/394

Allen MCQ

The unequivocal proof that DNA is the genetic material came from the experiments of :-

A

Griffith

B

Avery, Macleod & McCarty

C

Hershey and Chase

D

Watson and Crick

Question 311: Palette 311/394

Allen MCQ

Radioactive (3⁵5S) was detected in:-

A

Supernatant

B

Sediment

C

Both

D

Either (1) or (2)

Question 312: Palette 312/394

Allen MCQ

Which of the following is not a criteria for determination of genetic material?

A

Ability of replication

B

Chemically and structurally stable

C

It should be non-mutable

D

Ability to express itself in the form of Mendelian characters

Question 313: Palette 313/394

Allen MCQ

Which of the following is responsible for short life span and fast rate of mutation and evolution?

A

Presence of DNA

B

Presence of highly reactive RNA

C

Double stranded genetic material

D

Single stranded genetic material

Question 314: Palette 314/394

Allen MCQ

A transcription unit in DNA is defined primarily by three regions in DNA. These regions are:-

A

Promoter, regulator and structural gene

B

Promoter, structural gene and terminator

C

Promoter, regulator and terminator

D

Promoter, regulator and operator gene

Question 315: Palette 315/394

Allen MCQ

In transcription unit promoter and terminator are determined on the basis of :-

A

Coding strand

B

Template strand

C

Non-coding strand

D

Antisense strand

Question 316: Palette 316/394

Allen MCQ

In eukaryotes those DNA sequences that appear in mature or processed RNA are known as :-

A

Introns

B

Exons

C

Recons

D

Mutons

Question 317: Palette 317/394

Allen MCQ

Which of the following exclusive property of transcription found in RNA-polymerase?

A

Initiation

B

Elongation

C

Termination

D

Processing

Question 318: Palette 318/394

Allen MCQ

What is the length and constituent base of tail in functional m-RNA?

A

Poly U − 200-300 bp

B

Poly A − 200-300 bp

C

Poly C – 200-300 nucleotides

D

Poly A - 200-300 nucleotides

Question 319: Palette 319/394

Allen MCQ

DNA dependent RNA polymerases mediated synthesis of RNA over DNA called transcription. About it which of the following statement is wrong:-

A

In bacteria m-RNA does not required any processing to become active

B

In eukaryotes there is clear cut division of labour in RNA polymerases

C

Absence of introns in RNA of eukaryotes is reminiscent of antiquity

D

RNA polymerase - III is responsible for synthesis of snRNA

Question 320: Palette 320/394

Allen MCQ

At which of the following levels, regulation of gene expression in eukaryotes do not occur: -

A

Transcriptional initiation level

B

Processing level

C

Transport of ribosomal subunits from nucleus to cytoplasm level

D

Translation level

Question 321: Palette 321/394

Allen MCQ

In prokaryotes, predominant site for control of gene expression is the :-

A

Control of processing of primary transcript

B

Control of transcription initiation

C

Control of transport of m-RNA from nucleus to cytoplasm

D

Control of Translation BMI321

Question 322: Palette 322/394

Allen MCQ

Which of the following was not involved in deciphering of genetic code?

A

Physicist George Gamow's permutation combination of 4³ bases.

B

H.G. Khorana's based synthesis of RNA molecules with defined combination of bases.

C

Severo Ochoa enzyme for polymerising DNA with defined sequences.

D

Marshall Nirenberg's cell free system for protein synthesis.

Question 323: Palette 323/394

Allen MCQ

Which of the following mutation forms the genetic basis of proof that codon is a triplet and it is read in a continuous manner?

A

Chromosomal structural mutations

B

Chromosomal numerical mutations

C

Substitutional mutation

D

Frame shift insertion or deletion mutation BMI323

Question 324: Palette 324/394

Allen MCQ

Change in a single base pair of DNA can be termed as:-

A

Chromosomal aberrations

B

Point mutation

C

Genomatic mutation

D

Aneuploidy

Question 325: Palette 325/394

Allen MCQ

Which of the following cell cycle event is responsible for aneuploidy based on chromosomal disorders?

A

Failure of G₁ phase

B

Failure of DNA replication in S-phase

C

Failure of segregation/Disjunction

D

Failure of movement of chromosomes

Question 326: Palette 326/394

Allen MCQ

Which of the following cell cycle event is responsible for polyploidy phenomenon:-

A

Failure of karyokinesis

B

Failure of cytokinesis

C

Failure of segregation

D

Failure of non-disjunction

Question 327: Palette 327/394

Allen MCQ

Regarding to role of RNA in protein synthesis find out the odd one:-

A

m-RNA - provides the template

B

t-RNA - brings amino acids

C

r-RNA - read genetic code

D

sn-RNA splicing

Question 328: Palette 328/394

Allen MCQ

A m-RNA also has some additional sequences that are not translated called UTR. The function of UTR is :-

A

Charging of t-RNA

B

Formation of peptide bond

C

Helps in efficient translation

D

Helps in translocation

Question 329: Palette 329/394

Allen MCQ

The t-RNA move away from ribosomes after translocation of ribosome in relation to m-RNA, is known as :-

A

Acylated t-RNA

B

Peptidyl t-RNA

C

Deacylated t-RNA

D

Charged t-RNA

Question 330: Palette 330/394

Allen MCQ

The repressor of the operon is synthesized

A

All the time

B

Certain time

C

Non constitutively

D

None of these

Question 331: Palette 331/394

Allen MCQ

HGP was closely associated with the rapid development of a new area in biology called as :-

A

Biofortification

B

Bioinformatics

C

Biomining

D

Biotransformation

Question 332: Palette 332/394

Allen MCQ

Which of the following is not a goal of HGP?

A

Identify all the approximately 20,000- 25,000 genes

B

Store this information in database

C

Restrict the related technologies so that other sector do not benefited with it

D

Address the ethical, legal and social issues BMI332

Question 333: Palette 333/394

Allen MCQ

The human genome project was coordinated by :-

A

U.S. department of energy

B

National institute of health

C

Sanger centre

D

Both (1) and (2)

Question 334: Palette 334/394

Allen MCQ

Which of the following organism was not used as model organism is human genome project ?

A

Arabidopsis

B

Caenorhabditis elegans

C

Rice

D

Hyacinthus orientalis

Question 335: Palette 335/394

Allen MCQ

Approach of HGP focused on identifying all the genes that expressed as RNA is known as:-

A

Expressed sequence tags

B

Sequence annotation

C

Polymerase chain reaction

D

Dermatoglyphics

Question 336: Palette 336/394

Allen MCQ

Automated DNA sequencers worked on the principle of a method developed by:-

A

Watson

B

Chargaff

C

Frederick Sanger

D

Singer and Nicolson

Question 337: Palette 337/394

Allen MCQ

Regarding to salient features of human genome select out the incorrect one:-

A

Human genome contains 3164.7 million nucleotide bases.

B

Human genome contain 30,000 genes.

C

Y-chromosome has largest number of genes.

D

1.4 million locations are associated with SNPs.

Question 338: Palette 338/394

Allen MCQ

Match the following :-

Column-I	Column-II
(a) SNPs (b) Genes of chromosome No. 1 (c) Total No. of Human genes (d) Total nucleotides of human genome	(i) 3164.7 million (ii) 1.4 million (iii) 30000 (iv) 2968

A

a-ii, b-iii,c-iv, d-i

B

a-ii, b-iv, c-iii,d-i

C

a-ii, b-iv, c-i, d-iii

D

a-iv, b-ii, c-iii,d-i

Question 339: Palette 339/394

Allen MCQ

If an inheritable mutation is observed in a population at high frequency, it is referred as:-

A

DNA polyploidy

B

DNA polymorphism

C

DNA redundancy

D

Sequence annotation

Question 340: Palette 340/394

Allen MCQ

What is the basis of heredity?

A

Variations

B

Inheritance

C

Genetics

D

Recombination

Question 341: Palette 341/394

Allen MCQ

Which of the following is not the feature of human genome?

A

Less than 2 percent of the genome code for protein

B

Chromosome 1 has fewest gene (231)

C

Repetitive sequences make up very large portion of human genome

D

The functions are unknown for over 50% of the discovered genes

Question 342: Palette 342/394

Allen MCQ

A point mutation which involves change of A→G, C→T, C→G and T→A in DNA are :-

A

Transition, Transition, Transversion, Transversion

B

Transition, Transversion, Transition, Transversion

C

Transversion, Transition, Transversion, Transition

D

None of the above

Question 343: Palette 343/394

Allen MCQ

A segment of DNA has a base sequence : AAG, GAG, GAC, CAA, CCA–, Which one of the following sequence represents a frame shift mutation :-

A

AAG, GAG, GAC, CAA, CCA–

B

AAG, AGG, ACC, AAC, CA–

C

ACG, GAG, GAC, CAG, CC–

D

AAG, GCG, GAC, CAG, CC–

Question 344: Palette 344/394

Allen MCQ

If the DNA-codons are ATGATGATG and a cytosine base is inserted at the beginning which of the following would be the result:-

A

A non-sense mutation

B

CA, TGA, TGA, TG

C

CAT, GAT, GAT, G

D

C, ATG, ATG, ATG

Question 345: Palette 345/394

Allen MCQ

A completely radioactive double stranded DNA molecule undergoes two rounds of replication in a non-radioactive medium. What will be the radioactive status of the four daughter molecules?

A

All four still contain radioactivity

B

Radioactivity is lost from all four

C

Out of four, three contain radioactivity

D

Half of the number contain no radioactivity

Question 346: Palette 346/394

Allen MCQ

Consider the following sequence on m-RNA AUGGCAGUGCCA. Assuming that genetic code is overlap then how many number of codon may be present on this genetic code :-

A

9

B

10

C

8

D

11

Question 347: Palette 347/394

Allen MCQ

A normal DNA molecule is continuously replicate in ${ \mathsf { N } } ^ { 1 5 }$ medium than what is the % of lighter DNA in $4 ^ { \mathrm { t h } }$ generation?

A

12·5%

B

25%

C

0%

D

6·25%

Question 348: Palette 348/394

Allen MCQ

Find out the sequence of binding of the following amino acyl - t-RNA complexes during translation to an m-RNA transcribed by a DNA segment having the base sequence.
3' ATACCCATGGGG 5'. Choose the answer showing the correct order of alphabets:—
(a)

(b)

(c)

(d)

A

a, b, c, d

B

d, a, b, c

C

a, b, d, c

D

b, a, c, d

Question 349: Palette 349/394

Allen MCQ

KHORANA synthesized two RNAs (a) with repeat sequence of AB and (b) with repeat sequence of ABC the polypeptides coded by (a) and (b) are respectively :-

A

Homopolypeptides in both (a) and (b)

B

Heteropolypeptides in both

C

Homopolypeptide in (a) & heteropoly peptide in (b)

D

Heteropolypeptide in (a) & homopoly peptide in (b)

Question 350: Palette 350/394

Allen MCQ

Which of the following m-RNA will be translated completely?
(A) 5' AUG UGA UUA AAG AAA 3'
(B) 5' AUG AUA UUG CCC UGA 3'
(C) 5' AGU UCC AGA CUC UAA 3'
(D) 5' AUG UAC AGU AAC UAG 3'

A

(A) and (B)

B

(B) and (D)

C

(C) and (D)

D

(A) and (D)

Question 351: Palette 351/394

Allen MCQ

In a m-RNA sequence of $N _ { 2 } - b a s e$ is 5' AUG GUG CUC AAA' 3'. What is the correct sequence of anticodons which recognizes codons of m-RNA?

(a) (b)
(c) (d)

A

a, b, c, d

B

d, a, b, c

C

c, d, b, a

D

d, c, b, a

Question 352: Palette 352/394

Allen MCQ

Suppose evolution on earth has occurred in such a way that there are 96 amino acids instead of 20. DNA has 12 different types of bases and DNA synthesis occur in the same way as today. The minimum number of bases per codon would be:-

A

12

B

8

C

2

D

3

Question 353: Palette 353/394

Allen MCQ

Assume that their are 6 types of nitrogen bases available and 40 types of amino acid are available for protein synthesis, then in genetic code each codon made up by minimum how many nitrogen bases ?

A

3

B

4

C

5

D

2

Question 354: Palette 354/394

Allen MCQ

In a segment of DNA 3.2 kilobases are present. If DNA segment has 820 adenine molecules, then what will be number of cytosine ?

A

1560

B

1480

C

780

D

740

Question 355: Palette 355/394

Allen MCQ

Which statement is correct ?
(a) Degeneracy of code is related to, third member of codon.
(b) Single codon, codes for more than one amino acid.
(c) In codon first two bases are more specific.
(d) In codons, third base is wobble.
(e) Codon is nearly universal.

A

a, b, c, d, e

B

a, b, d

C

a, c, d

D

a, c, d, e

Question 356: Palette 356/394

Allen MCQ

Both the strand of DNA are not copied during transcription because :-

A

If both strands act as a template, they would code for RNA with different sequence.

B

The two RNA molecules, if produced simultaneously would be complementary to each other, hence would form a double stranded RNA.

C

They would code, for RNA molecules with same sequences.

D

Both (1) and (2) are correct BMI358

Question 357: Palette 357/394

Allen MCQ

The salient features of B-DNA are :—
(i) It is made of two polynucleotide chain
(ii) Back bone is constituted by sugar and nitrogen base
(iii)Two chains have parallel polarity
(iv) Bases in two strands are paired through H-bonds
(v) The two chains are coiled in a left handed fashion

A

i, iv, v

B

i, iv

C

i, ii, v

D

i, ii, iii, iv, v

Question 358: Palette 358/394

Allen MCQ

Which is incorrect for genetic code:-
(i) The codon is triplet
(ii) 64 codons code for amino acids
(iii) Genetic code is unambiguous
(iv) Genetic code is nearly universal
(v) AUG has dual functions

A

only ii

B

ii & iii

C

iii, iv + v

D

All are correct

Question 359: Palette 359/394

Allen MCQ

Which is correct ?
(i) t-RNA has an anticodon loop that has bases complementary to the codon.
(ii) t-RNA has an amino acid acceptor end.
(iii) t-RNA are specific for each amino acid.
(iv) For initiation, there is specific t-RNA that is referred to as initiator t-RNA.
(v) For termination there is specific t-RNA that is referred to as terminator t-RNA.

A

i, ii

B

i, ii, iii

C

i, ii, iii, iv

D

i, ii, iii, iv, v

Question 360: Palette 360/394

Allen MCQ

E.coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because:-

A

They cannot synthesize functional beta galactosidase.

B

They cannot transport lactose from the medium into the cell.

C

The lac operon is constitutively active in these cells.

D

In the presence of glucose, E. coli cells do not utilize lactose.

Question 361: Palette 361/394

Allen MCQ

DNA fragments separated by gel electrophoresis are shown. Mark the correct statement :-

A

Band 3 contains more positively charged DNA molecule than 1

B

Band '3' indicates more charge density than 1 and 2

C

Band 1 has longer DNA fragment than 2 and 3

D

All the bands have equal length and charges but differ in base composition

Question 362: Palette 362/394

Allen MCQ

Amino acid sequence, in protein synthesis is decided by the sequence of:-

A

t-RNA

B

m-RNA

C

c-DNA

D

r-RNA

Question 363: Palette 363/394

Allen MCQ

One gene-one enzyme hypothesis was postulated by:-

A

R. Franklin

B

Hershey and Chase

C

A. Garrod

D

Beadle and Tatum

Question 364: Palette 364/394

Allen MCQ

One turn of the helix in a B-form DNA is approximately:-

A

20 nm

B

0.34 nm

C

3.4 nm

D

2 nm

Question 365: Palette 365/394

Allen MCQ

Antiparallel strands of a DNA molecule means that :-

A

one strand turns anti-clockwise

B

the phosphate groups of two DNA strands, at their ends, share the same position

C

the phosphate groups at the start of two DNA strands are in opposite position (pole)

D

one strand turns clockwise

Question 366: Palette 366/394

Allen MCQ

Cri-du-chat syndrome in humans is caused by the :-

A

Fertilization of an XX egg by a normal Y-bearing sperm

B

Loss of half of the short arm of chromosome 5

C

Loss of half of the long arm of chromosome 5

D

Trisomy of 21st chromosome

Question 367: Palette 367/394

Allen MCQ

Triticale, the first man-made cereal crop, has been obtained by crossing wheat with:—

A

Rye

B

Pearl millet

C

Sugarcane

D

Barley

Question 368: Palette 368/394

Allen MCQ

Differentiation of organs and tissues in a developing organism, is association with :-

A

Developmental mutations

B

Differential expression of genes

C

Lethal mutations

D

Deletion of genes

Question 369: Palette 369/394

Allen MCQ

Molecular basis of organ differentiation depends on the modulation in transcription by:-

A

RNA polymerase

B

Ribosome

C

Transcription factor

D

Anticodon

Question 370: Palette 370/394

Allen MCQ

The Okazaki fragments in DNA chain growth:-

A

Result in transcription.

B

Polymerize in the 3'-to-5' direction and forms replication fork.

C

Prove semi-conservative nature of DNA replication.

D

Polymerize in the 5'-to-3' direction and explain 3'-to-5' DNA replication.

Question 371: Palette 371/394

Allen MCQ

The two polynucleotide chains in DNA are :-

A

Parallel

B

Discontinuous

C

Antiparallel

D

Semiconservative

Question 372: Palette 372/394

Allen MCQ

In the hexaploid wheat, the haploid (n) and basic (x) numbers of chromosomes are :-

A

n = 7 and x = 21

B

n = 21 and x = 21

C

n = 21 and x = 14

D

n = 21 and x = 7

Question 373: Palette 373/394

Allen MCQ

Which of the following nitrogen base is not found in DNA?

A

Thymine

B

Cytosine

C

Guanine

D

Uracil

Question 374: Palette 374/394

Allen MCQ

Polysome is formed by :-

A

A ribosome with several subunits

B

Ribosomes attached to each other in a linear arrangement

C

Several ribosomes attached to a single mRNA

D

Many ribosomes attached to a strand of endoplasmic reticulum

Question 375: Palette 375/394

Allen MCQ

Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?

A

Guanine, Adenine – Purines

B

Adenine, Thymine – Purines

C

Thymine, Uracil – Pyrimidines

D

Uracil, Cytosine – Pyrimidines

Question 376: Palette 376/394

Allen MCQ

In the DNA molecule :-

A

the proportion of Adenine in relation to thymine varies with the organism

B

there are two strands which run antiparallel one in 5' →3' direction and other in 3' → 5'

C

the total amount of purine nucleotides and pyrimidine nucleotides is not always equal

D

there are two strands which run parallel in the 5' →3' direction

Question 377: Palette 377/394

Allen MCQ

Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?

A

AUG,ACG - Start/Methionine

B

UUA, UCA – Leucine

C

GUU, GCU – Alanine

D

UAG, UGA – Stop

Question 378: Palette 378/394

Allen MCQ

Which of the following bond is not related to nucleic acid ?

A

H-bond

B

Ester bond

C

Glycosidic bond

D

Peptide bond

Question 379: Palette 379/394

Allen MCQ

Haploids are more suitable for mutation studies than the diploids. This is because :-

A

Haploids are more abundant in nature than diploids.

B

All mutations, whether dominant or recessive are expressed in haploids.

C

Haploids are reproductively more stable than diploids.

D

Mutagens penetrate in haploids more effectively than in diploids.

Question 380: Palette 380/394

Allen MCQ

What is not true for genetic code ?

A

It is unambiguous

B

A codon in mRNA is read in a noncontiguous fashion

C

It is nearly universal

D

It is degenerate

Question 381: Palette 381/394

Allen MCQ

Removal of introns and joining the exons in a defined order in a transcription unit is called:-

A

Capping

B

Splicing

C

Tailing

D

Transformation

Question 382: Palette 382/394

Allen MCQ

Semiconservative replication of DNA was first demonstrated in :-

A

Salmonella typhimurium

B

Drosophila melanogaster

C

Escherichia coli

D

Streptococcus pneumoniae

Question 383: Palette 383/394

Allen MCQ

Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet" ?

A

Beadle and Tatum

B

Nirenberg and Matthaei

C

Hershey and Chase

D

Morgan and Sturtevant

Question 384: Palette 384/394

Allen MCQ

Point mutation involves :-

A

Deletion

B

Insertion

C

Change in single base pair

D

Duplication

Question 385: Palette 385/394

Allen MCQ

Select the two correct statements out of the four (a-d) given below about lac operon:
(a) Glucose or galactose may bind with the repressor and inactivated.
(b) In the absence of lactose the repressor binds with the operator region.
(c) The z-gene codes for permease.
(d) This was elucidated by Francois Jacob and Jacque Monod. The correct statements are :-

A

(b) and (d)

B

(a) and (b)

C

(b) and (c)

D

(a) and (c)

Question 386: Palette 386/394

Allen MCQ

Satellite DNA is useful tool in :-

A

Forensic science

B

Genetic engineering

C

Organ transplantation

D

Sex determination

Question 387: Palette 387/394

Allen MCQ

The one aspect which is not a salient feature of genetic code, is its being :-

A

Universal

B

Specific

C

Degenerate

D

Ambiguous

Question 388: Palette 388/394

Allen MCQ

Which one of the following does not follow the central dogma of molecular biology?

A

Chlamydomonas

B

HIV

C

Pea

D

Mucor

Question 389: Palette 389/394

Allen MCQ

PCR and Restriction Fragment Length Polymorphism are the methods for: -

A

DNA sequencing

B

Genetic fingerprinting

C

Study of enzymes

D

Genetic transformation

Question 390: Palette 390/394

Allen MCQ

What is it that forms the basis of DNA Fingerprinting?

A

The relative amount of DNA in the ridges and grooves of the fingerprints.

B

Satellite DNA occurring as highly repeated short DNA segments

C

The relative proportions of purines and pyrimidines in DNA

D

The relative difference in the DNA occurrence in blood, skin and saliva BMI202

Question 391: Palette 391/394

Allen MCQ

Read the following four statements (A-D):
(A) In transcription, adenosine pairs with uracil.
(B) Regulation of lac operon by repressor is referred to as positive regulation.
(C) The human genome has approximately 50,000 genes.
(D) Haemophilia is a sex-linked recessive disease. How many of the above statements are right?

A

Four

B

One

C

Two

D

Three

Question 392: Palette 392/394

Allen MCQ

Which one of the following is a wrong statement regarding mutations?

A

UV and Gamma rays are mutagens

B

Change in a single base pair of DNA does not cause mutation

C

Deletion and insertion of base pairs cause frame-shift mutations.

D

Cancer cells commonly show chromosomal aberrations.

Question 393: Palette 393/394

Allen MCQ

Which enzyme/s will be produced in a cell in which there is a nonsense mutation in the lac Y-gene?

A

Lactose permease and transacetylase

B

β-galactosidase

C

Lactose permease

D

Catalase

Question 394: Palette 394/394

Allen MCQ

DNA fragments generated by the restriction endonucleases in a chemical reaction can be separated by :-

A

Restriction mapping

B

Centrifugation

C

Polymerase chain reaction

D

Electrophoresis