Question 1: Palette 1/38

NEET 2025 MCQ

Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).

Assertion (A) :

undergoes $S_N 2$ reaction faster than

Reason (R) : lodine is a better leaving group because of its large size. In the light of the above statements, choose the correct answer from the options given below:

A

$\mathbf{A}$ is true but $\mathbf{R}$ is false

B

$\mathbf{A}$ is false but $\mathbf{R}$ is true

C

Both $\mathbf{A}$ and $\mathbf{R}$ are true and $\mathbf{R}$ is the correct explanation of $\mathbf{A}$

D

Both $\mathbf{A}$ and $\mathbf{R}$ are true but $\mathbf{R}$ is not the correct explanation of $\mathbf{A}$

Question 2: Palette 2/38

NEET 2025 MCQ

The major product of the following reaction is

A

B

C

D

Question 3: Palette 3/38

NEET 2024 MCQ

The major product $\mathrm{C}$ in the below mentioned reaction is:

$\mathrm{CH}_3 \mathrm{CH}_2 \mathrm{CH}_2 \mathrm{Br} \xrightarrow[\Delta]{\text { alc. } \mathrm{KOH}} \mathrm{A} \xrightarrow{\mathrm{HBr}} \mathrm{B} \xrightarrow[\Delta]{\text { aq. } \mathrm{KOH}} \mathrm{C}$

A

Propan-1-ol

B

Propan-2-ol

C

Propane

D

Propyne

Question 4: Palette 4/38

NEET 2024 MCQ

The following reaction method

is not suitable for the preparation of the corresponding haloarene products, due to high reactivity of halogen, when X is :

A

F

B

I

C

Cl

D

Br

Question 5: Palette 5/38

NEET 2024 MCQ

The compound that will undergo S_N1 reaction with the fastest rate is

A

B

C

D

Question 6: Palette 6/38

NEET 2024 MCQ

Identify the major product C formed in the following reaction sequence :

$ \mathrm{CH}_3-\mathrm{CH}_2-\mathrm{CH}_2-\mathrm{I} \xrightarrow{\mathrm{NaCN}} \mathrm{A} $

$\mathrm{\mathrel{\mathop{\kern0pt\longrightarrow} \limits_{Partial\,hydrolysis}^{O{H^ - }}} B\mathrel{\mathop{\kern0pt\longrightarrow} \limits_{B{r_2}}^{NaOH}} \mathop C\limits_{(major)}}$

A

propylamine

B

butylamine

C

butanamide

D

$\alpha$-bromobutanoic acid

Question 7: Palette 7/38

NEET 2023 MCQ

Which amongst the following reactions of alkyl halides produces isonitrile as a major product?

(A) $\mathrm{R-X+HCN\to}$

(B) $\mathrm{R-X+AgCN\to}$

(C) $\mathrm{R-X+KCN\to}$

(D) $\mathrm{R-X+NaCN\mathrel{\mathop{\kern0pt\longrightarrow} \limits_{{C_2}{H_5}OH}^{{H_2}O}}}$

Choose the most appropriate answer from the options given below:

A

(D) only

B

(C) and (D) only

C

(B) only

D

(A) and (B) only

Question 8: Palette 8/38

NEET 2023 MCQ

Choose the correct sequence of reagents in the conversion of 4-nitrotoluene to 2-bromotoluene.

A

$\mathrm{NaNO}_2 / \mathrm{HCl} ; \mathrm{Sn} / \mathrm{HCl} ; \mathrm{Br}_2 ; \mathrm{H}_2 \mathrm{O} / \mathrm{H}_3 \mathrm{PO}_2$

B

$\mathrm{Sn} / \mathrm{HCl} ; \mathrm{NaNO}_2 / \mathrm{HCl} ; \mathrm{Br}_2 ; \mathrm{H}_2 \mathrm{O} / \mathrm{H}_3 \mathrm{PO}_2$

C

$\mathrm{Br}_2 ; \mathrm{Sn} / \mathrm{HCl} ; \mathrm{NaNO}_2 / \mathrm{HCl} ; \mathrm{H}_2 \mathrm{O} / \mathrm{H}_3 \mathrm{PO}_2$

D

$\mathrm{Sn} / \mathrm{HCl} ; \mathrm{Br}_2 ; \mathrm{NaNO}_2 / \mathrm{HCl} ; \mathrm{H}_2 \mathrm{O} / \mathrm{H}_3 \mathrm{PO}_2$

Question 9: Palette 9/38

NEET 2023 MCQ

Identify the product in the following reaction

A

B

C

D

Question 10: Palette 10/38

NEET 2023 MCQ

Identify 'X' in the following reaction.

A

B

C

D

Question 11: Palette 11/38

NEET 2023 MCQ

The given compound

is an example of _________.

A

aryl halide

B

allylic halide

C

vinylic halide

D

benzylic halide

Question 12: Palette 12/38

NEET 2021 MCQ

The major product of the following chemical reaction is :

A

B

C

D

Question 13: Palette 13/38

NEET 2021 MCQ

The major product formed in dehydrohalogenation reaction of 2-Bromo pentane is Pent-2-ene. This product formation is based on?

A

Huckel's Rule

B

Saytzeff's Rule

C

Hund's Rule

D

Hofmann Rule

Question 14: Palette 14/38

NEET 2020 MCQ

Which of the following alkane cannot be made in good yield by Wurtz reaction?

A

2, 3-Dimethylbutane

B

n-Heptane

C

n-Butane

D

n-Hexane

Question 15: Palette 15/38

NEET 2020 MCQ

Elimination reaction of 2-Bromo-pentane to form pent-2-ene is :
(A) $\beta $-Elimination reaction
(B) Follows Zaitsev rule
(C) Dehydrohalogenation reaction
(D) Dehydration reaction

A

(A), (C), (D)

B

(B), (C), (D)

C

(A), (B), (D)

D

(A), (B), (C)

Question 16: Palette 16/38

NEET 2018 MCQ

The compound C₇H₈ undergoes the following reactions :
The product ‘C’ is

A

m–bromotoluene

B

o–bromotoluene

C

3–bromo–2,4,6–trichlorotoluene

D

p–bromotoluene

Question 17: Palette 17/38

NEET 2017 MCQ

Identify $A$ and predict the type of reaction.

A

B

C

D

Question 18: Palette 18/38

NEET 2016 MCQ

Consider the reaction,
CH₃CH₂CH₂Br + NaCN $ \to $ CH₃CH₂CH₂CN + NaBr

This reaction will be the fastest in

A

ethanol

B

methanol

C

N, N' -dimethylformamide (DMF)

D

Water

Question 19: Palette 19/38

NEET 2016 MCQ

Which of the following biphenyls is optically active ?

A

B

C

D

Question 20: Palette 20/38

NEET 2015 MCQ

In an S_N1 reaction on chiral centers, there is

A

inversion more than retention leading to partial racemisation

B

100% retention

C

100% inversion

D

100% racemisation

Question 21: Palette 21/38

NEET 2015 MCQ

The reaction of C₆H₅CH $=$ CHCH₃ with HBr produces

A

B

C

D

Question 22: Palette 22/38

NEET 2014 MCQ

Which of the following compounds will undergo racemisation when solution of KOH hydrolyses?

A

(i) and (ii)

B

(ii) and (iv)

C

(iv)

D

(i) and (iv)

Question 23: Palette 23/38

NEET 2012 MCQ

In the replacement reaction

The reaction will be most favourable if M happens to be

A

Na

B

K

C

Rb

D

Li

Question 24: Palette 24/38

NEET 2011 MCQ

Which of the following compounds undergoes nucleophilic substitution reaction most easily?

A

B

C

D

Question 25: Palette 25/38

NEET 2011 MCQ

Consider the reactions.

The mechanisms of reactions (i) and (ii) are respectively

A

S_N1   and  S_N2

B

S_N1   and  S_N1

C

S_N2   and  S_N2

D

S_N2   and  S_N1

Question 26: Palette 26/38

NEET 2010 MCQ

In the following reaction

the product 'X' is

A

C₆H₅CH₂OCH₂C₆H₅

B

C₆H₅CH₂OH

C

C₆H₅CH₃

D

C₆H₅CH₂CH₂C₆H₅

Question 27: Palette 27/38

NEET 2010 MCQ

Which one is most reactive towards S_N1 reaction?

A

C₆H₅CH(C₆H₅)Br

B

C₆H₅CH(CH₃)Br

C

C₆H₅C(CH₃)(C₆H₅)Br

D

C₆H₅CH₂Br

Question 28: Palette 28/38

NEET 2010 MCQ

The correct order of increasing reactivity of

C$-$X bond towards nucleophile in the following compounds is

A

I < II < IV < III

B

II < III < I < IV

C

IV < III < I < II

D

III < II < I < IV

Question 29: Palette 29/38

NEET 2009 MCQ

Which of the following reactions is an example of nucleophilic substitution reaction?

A

2RX + 2Na $ \to $ R $-$ R + 2NaX

B

RX + H₂ $ \to $ RH + HX

C

RX + Mg $ \to $ RMgX

D

RX + KOH $ \to $ ROH + KX

Question 30: Palette 30/38

NEET 2008 MCQ

In a S_N2 substitution reaction of the type
R $-$ Br + Cl^$-$ $\buildrel {DMF} \over \longrightarrow $ R$-$Cl + Br^$-$
which one of the following has the highest relative rate?

A

B

CH₃CH₂Br

C

CH₃CH₂CH₂Br

D

Question 31: Palette 31/38

NEET 2007 MCQ

CH₃ $-$ CHCl $-$ CH₂ $-$ CH₃ has a chiral centre. Which one of the following represents its R-configuration?

A

B

C

D

Question 32: Palette 32/38

NEET 2006 MCQ

Which of the following is not chiral?

A

2-Hydroxypropanoic acid

B

2-Butanol

C

2,3-Dibromopentane

D

3-Bromopentane

Question 33: Palette 33/38

NEET 2005 MCQ

Which of the following undergoes nucleophilic substitution exclusively by S_N1 mechanism?

A

Ethyl chloride

B

Isopropyl chloride

C

Chlorobenzene

D

Benzyl chloride

Question 34: Palette 34/38

NEET 2004 MCQ

Which of the following is least reactive in a nucleophilic sibstitution reaction?

A

(CH₃)₃C $-$ Cl

B

CH₂$=$CHCl

C

CH₃CH₂Cl

D

CH₂$=$CHCH₂Cl

Question 35: Palette 35/38

NEET 2002 MCQ

Reactivity order of halides for dehydrologenation is

A

$R - F > R - Cl > R - Br > R - {\rm I}$

B

$R - {\rm I} > R - Br > R - Cl > R - F$

C

$R - {\rm I} > R - Cl > R - Br > R - F$

D

$R - F > R - {\rm I} > R - Br > R - Cl$

Question 36: Palette 36/38

NEET 2002 MCQ

Z in the above reaction sequence is

A

CH₃CH₂CH₂NHCOCH₃

B

CH₃CH₂CH₂NH₂

C

CH₃CH₂CH₂CONHCH₃

D

CH₃CH₂CH₂CONHCOCH₃

Question 37: Palette 37/38

NEET 2001 MCQ

An organic compound A(C₄H₉Cl) on reaction with Na/diethyl ether gives a hydrocarbon which on monochlorination gives only one chloro derivative then, A is

A

t-butyl chloride

B

s-butyl chloride

C

iso-butyl chloride

D

n-butyl chloride

Question 38: Palette 38/38

NEET 2001 MCQ

obtained by chlorination of n-butane will be

A

meso form

B

racemic mixture

C

d-form

D

$l$-form